Polygalacic acid

ChemicalBook > CAS DataBase List > Polygalacic acid

Product Name: Polygalacic acid
CAS No.: 22338-71-2
Chemical Name: Polygalacic acid
Synonyms: Polygalacic;Polygalacicaci;Polygalacic acid;Virgaureagenin G;Polygalacic acid, >=98%;Virgaureagenin G，Polygalacic acid;(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid;Polygalacic acid, 98%, from Polygala tenuifolia Willd.;(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid;Olean-12-en-28-oicacid, 2,3,16,23-tetrahydroxy-, (2β,3β,4,16)-
CBNumber: CB21040708
Molecular Formula: C30H48O6
Formula Weight: 504.7
MOL File: 22338-71-2.mol

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Polygalacic acid Property

Melting point:: 300-305 °C (sublm)
Boiling point:: 638.1±55.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: 4°C, protect from light
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
pka: 4.41±0.70(Predicted)
color: White to off-white

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Safety

HS Code: 29163990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Usbiological

Product number: 300805
Product name: Polygalacic acid
Packaging: 20mg
Price: $490
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: SHG0005843
Product name: (2B,3B,4A,16A)-2,3,16,23-TETRAHYDROXYOLEAN-12-EN-28-OIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $503.58
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 74064
Product name: Polygalacicacid
Purity: 98%
Packaging: 20mg
Price: $533
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb105678
Product name: Polygalacic acid
Purity: >98%,Standard References Grade
Packaging: 20mg
Price: $569.5
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb594205
Product name: Virgaureagenin G
Packaging: 5mg
Price: $596.7
Updated: 2021/12/16

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Polygalacic acid Chemical Properties,Usage,Production

Uses

Polygalacic acid can be used to calm the nerves, eliminate phlegm, reduce swelling, etc. It is mostly used clinically to treat bronchitis, induce labor, and induce labor.

Biological Activity

Polygalacic acid is a triterpenoid tetrahydroxy acid isolated from Polygala paenea L.. It (0-100μM; 24h) can significantly reduce the mRNA expression of MMP-3, MMP-9, MMP-13 and COX-2, and the expression of these factors can be significantly increased by IL-1β in a dose-dependent manner .

in vitro

Polygalacic acid (0-100 μM; 24 hours) significantly decreases the mRNAexpressions of MMP-3, MMP-9, MMP-13, and COX-2, which are significantly increased by IL-1β, in a In a dose-dependent manner. Polygalacic acid (0-100 μM; 6 hours) decreases the expression of phosphor-p38, phosphor-Erk, and phosphor-Jnk induced by IL-1β, phosphor-p65 is not reduced by polygalacic acid.

RT-PCR

Cell Line:	Chondrocyte cells
Concentration:	50 μM; 100 μM
Incubation Time:	24 hours
Result:	Suppressed IL-1β-induced COX-2, MMP3, MMP9, and MMP13 mRNA expression.

Western Blot Analysis

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Cell Line:	Chondrocyte cells
Concentration:	50 μM; 100 μM
Incubation Time :	6 hours
Result:	Inhibited the IL-1β-induced activation of the MAPK pathway in chondrocytes.

Polygalacic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Polygalacic acid manufacturers

Career Henan Chemical Co

Product: Polygalacic acid 22338-71-2
Price: US $1.00/kg
Min. Order: 1g
Purity: 99%
Supply Ability: 100KG
Release date: 2018-12-24

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Polygalacic acid

Polygalacic

(2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid

Olean-12-en-28-oicacid, 2,3,16,23-tetrahydroxy-, (2β,3β,4,16)-

Virgaureagenin G

(4R)-2β,3β,16α,23-Tetrahydroxyolean-12-en-28-oic acid

Polygalacic acid or (2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid

Polygalacic acid (2b,3b,4a,16a)-2,3,16,23-Tetrahydroxyolean-12-en-28-oic acid

Polygalacic acid, >=98%

(4AR,5R,6aS,6bR,9R,10R,11S,12aR,12bR,14bR)-5,10,11-trihydroxy-9-(hydroxymethyl)-2,2,6a,6b,9,12

Polygalacic acid, 98%, from Polygala tenuifolia Willd.

Polygalacicaci

Olean-12-en-28-oic acid, 2,3,16,23-tetrahydroxy-, (2β,3β,4α,16α)-

Virgaureagenin G，Polygalacic acid

22338-71-2

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract