Adebrelimab

Product Name: Adebrelimab
CAS No.: 2247114-85-6
Chemical Name: Adebrelimab
Synonyms: Adebrelimab;Adebrelimab (anti-PD-L1);Research Grade Adebrelimab;Research Grade Adebrelimab (DHJ70108)
CBNumber: CB210616943
Formula Weight: 0
MOL File: Mol file

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Adebrelimab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Adebrelimab Chemical Properties,Usage,Production

Uses

Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 (PD-1/PD-L1) antibody. Adebrelimab has promising antitumor activity in solid tumors including extensive-stage small-cell lung cancer (SCLC)[1][2].

in vivo

Adebrelimab (SHR-1316; 200 μg; three times a week; for 21 days) shows inhibition effects on tumor growth^[1].

Animal Model:	Pathogen free (SPF) BALB/c nude female mice (aged 5-6 weeks) injected with SK-BR-3 cells^[1]
Dosage:	200 μg
Administration:	Three times a week; for 21 days
Result:	Significantly inhibited tumor growth.

References

[1] Zhiwei Liu, et al. The Synergistic Effects of Pyrotinib and SHR-1316 on HER2-positve breast cancer. Research Square. May 19th, 2022.
[2] Wanpu Yan, et al. Adebrelimab (SHR-1316) in combination with chemotherapy as perioperative treatment in patients with resectable stage II-III NSCLC: an open-label, multicenter, phase 1b trial. J Thorac Oncol. 2022 Sep 30;S1556-0864(22)01822-6. DOI:10.1016/j.jtho.2022.09.222

Adebrelimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Adebrelimab Suppliers

China 15 United States 1 Global 16

Shanghai YuanYe Biotechnology Co., Ltd.

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Wuhan Chemstan Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Biolab Reagents

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Shanghai Yifei Biotechnology Co. , Ltd.

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Wanxin Biotechnology (Jiaxing) Co., LTD

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Atagenix Laboratories

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AntibodySystem Laboratories SAS

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2247114-85-6, AdebrelimabRelated Search:

Zanidatamab Teclistamab Dusigitumab Spartalizumab Iparomlimab Elgemtumab Maftivimab Pidilizumab Socazolimab Osocimab

Adebrelimab

Research Grade Adebrelimab (DHJ70108)

Research Grade Adebrelimab

Adebrelimab (anti-PD-L1)

2247114-85-6