ChemicalBook > CAS DataBase List > Osocimab
Osocimab
- Product Name
- Osocimab
- CAS No.
- 2056878-75-0
- Chemical Name
- Osocimab
- Synonyms
- Osocimab;BAY 1213790;Research Grade Osocimab;Osocimab?(anti-Factor XI);Research Grade Osocimab (DHC04201)
- CBNumber
- CB88081108
- Formula Weight
- 0
- MOL File
- Mol file
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Osocimab Property
- form
- Liquid
- color
- Colorless to light yellow
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Osocimab Chemical Properties,Usage,Production
Uses
Osocimab (BAY 1213790), an anti-FXIa antibody (Ki=2.4 nM; EC50=0.2 nM). FXI inhibition may reduce the risk of thrombosis. Osocimab inhibits thrombin generation, and prolongs activated partial thromboplastin time. Osocimab exhibits anticoagulant effects[1].
References
[1] Schaefer M, et al. Allosteric Inhibition as a New Mode of Action for BAY 1213790, a Neutralizing Antibody Targeting the Activated Form of Coagulation Factor XI. J Mol Biol. 2019 Dec 6;431(24):4817-4833. DOI:10.1016/j.jmb.2019.09.008
Osocimab Preparation Products And Raw materials
Raw materials
Preparation Products
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Osocimab Suppliers
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