ChemicalBook > CAS DataBase List > 2,5-DIBROMO-3-AMINOPYRIDINE

2,5-DIBROMO-3-AMINOPYRIDINE

Product Name
2,5-DIBROMO-3-AMINOPYRIDINE
CAS No.
90902-84-4
Chemical Name
2,5-DIBROMO-3-AMINOPYRIDINE
Synonyms
2,5-Dibromopyridin-3-amine;2,5-dibromo-3-pyridinamine;2,5-DIBROMO-3-AMINOPYRIDINE;3-Amino-2,5-dibromopyridi...;3-Pyridinamine, 2,5-dibromo-;2,5-DIBROMO-PYRIDIN-3-YLAMINE;3-Amino-2,5-dibromopyridine≥ 98% (HPLC);2,5-DIBROMO-3-AMINOPYRIDINE ISO 9001：2015 REACH
CBNumber
CB21076002
Molecular Formula
C5H4Br2N2
Formula Weight
251.91
MOL File
90902-84-4.mol
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2,5-DIBROMO-3-AMINOPYRIDINE Property

Melting point:
152.0 to 156.0 °C
Boiling point:
325.0±37.0 °C(Predicted)
Density 
2.147±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
-0.56±0.10(Predicted)
form 
powder to crystal
color 
White to Brown
InChI
InChI=1S/C5H4Br2N2/c6-3-1-4(8)5(7)9-2-3/h1-2H,8H2
InChIKey
VHGBUYMPBFPXQM-UHFFFAOYSA-N
SMILES
C1(Br)=NC=C(Br)C=C1N
CAS DataBase Reference
90902-84-4
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Safety

Hazard Codes 
Xi,T
Risk Statements 
25-41
Safety Statements 
26-39-45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000414
Product name
2,5-Dibromo-pyridin-3-ylamine
Purity
Aldrich
Packaging
1g
Price
$747
Updated
2025/07/31
TCI Chemical
Product number
A3048
Product name
3-Amino-2,5-dibromopyridine
Purity
>98.0%(GC)
Packaging
1g
Price
$61
Updated
2025/07/31
TCI Chemical
Product number
A3048
Product name
3-Amino-2,5-dibromopyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$184
Updated
2025/07/31
TRC
Product number
B426193
Product name
2,5-Dibromopyridin-3-amine
Packaging
10mg
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-0052143
Product name
2,5-Dibromopyridin-3-amine
Purity
99.34%
Packaging
5g
Price
$57
Updated
2021/12/16
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2,5-DIBROMO-3-AMINOPYRIDINE Chemical Properties,Usage,Production

Chemical Properties

Brown solid

Uses

3-Amino-2,5-dibromopyridine is used as a pharmaceutical synthesis intermediate.

Synthesis

15862-37-0

90902-84-4

(b) Synthesis of 2,5-dibromo-3-aminopyridine: 2,5-dibromo-3-nitropyridine (2.5 g, 8.87 mmol) was dissolved in acetic acid (10 mL) and stirred until completely dissolved. Powdered iron (2.476 g, 44.3 mmol) was then added and the reaction mixture was heated to 80 °C under vigorous stirring and maintained for 15 min. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad to remove solid impurities and the filter cake was washed with ether and ethyl acetate (EtOAc). The organic layers were combined and washed sequentially with water and saturated brine to remove water-soluble impurities. The organic layers were dried over anhydrous magnesium sulfate, filtered and concentrated to give the crude product. The crude product was purified by silica gel column chromatography using 0-30% ethyl acetate/hexane gradient elution to collect the target components, and concentrated under reduced pressure to give 2,5-dibromopyridin-3-amine (1.7 g, 6.75 mmol, 76% yield) as a white solid. The mass spectrum (electrospray positive ion mode) showed m/z 252 ([M+H]+).

References

[1] Bulletin des Societes Chimiques Belges, 1988, vol. 97, # 1, p. 51 - 54
[2] Patent: WO2008/128961, 2008, A1. Location in patent: Page/Page column 37; 73
[3] Journal of Medicinal Chemistry, 2010, vol. 53, # 10, p. 3927 - 3936
[4] Patent: WO2007/107758, 2007, A1. Location in patent: Page/Page column 125
[5] Journal of the Chemical Society, 1952, p. 2042,2044

2,5-DIBROMO-3-AMINOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-DIBROMO-3-AMINOPYRIDINE Suppliers

Americas 1 China 93 Europe 1 India 6 Japan 1 United Kingdom 1 United States 12 Global 115
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
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View Lastest Price from 2,5-DIBROMO-3-AMINOPYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2,5-Dibromo-pyridin-3-ylamine 90902-84-4
Price
US $1.00/Kg
Min. Order
1KG
Purity
98%
Supply Ability
20T
Release date
2019-12-26
Shaanxi Dideu Medichem Co. Ltd
Product
2,5-Dibromo-pyridin-3-ylamine 90902-84-4
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-12
Career Henan Chemical Co
Product
2,5-DIBROMO-3-AMINOPYRIDINE 90902-84-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kgs
Release date
2020-02-18

90902-84-4, 2,5-DIBROMO-3-AMINOPYRIDINERelated Search:

PYRAZOLO[1,5-A]PYRIMIDINE-2-CARBOXYLIC ACID (S)-1-(4-FLUOROPHENYL)ETHANOL 1-Methyl-1H-pyrazol-4-aMine dihydrochloride 6-BROMO-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 1,3-Bis(4,5-dihydro-2-oxazolyl)benzene (R)-1-(4-FLUOROPHENYL)ETHANOL 4-bromo-1-methylpyrazole-3-carboxy acid 5-HYDROXY-1-METHYL-1H-PYRAZOLE-3-CARBOXYLIC ACID METHYL ESTER 4,5-Dihydrooxazole, 2-vinyl- 1-methyl-1H-pyrazol-4-amine 2,4-DIBROMO-3-AMINOPYRIDINE 2,5-Dibromo-3-nitropyridine 2,3,6-TRIBROMO-4-METHOXY-5-NITROPYRIDINE 2,5-DIBROMO-3-AMINOPYRIDINE 3-BROMO-2,6-DIMETHYL-5-NITROPYRIDIN-4-OL 2,5-Dibromo-4-methyl-3-nitropyridine 2,5,6-TRIBROMOPYRIDIN-3-YLAMINE 2,6-DIBROMO-3-AMINOPYRIDINE

  • 2,5-DIBROMO-PYRIDIN-3-YLAMINE
  • 2,5-DIBROMO-3-AMINOPYRIDINE
  • 2,5-dibromo-3-pyridinamine
  • 2,5-Dibromopyridin-3-amine
  • 3-Amino-2,5-dibromopyridi...
  • 3-Amino-2,5-dibromopyridine≥ 98% (HPLC)
  • 3-Pyridinamine, 2,5-dibromo-
  • 2,5-DIBROMO-3-AMINOPYRIDINE ISO 9001：2015 REACH
  • 90902-84-4
  • Pyridine