Dibenzepin

Product Name: Dibenzepin
CAS No.: 4498-32-2
Chemical Name: Dibenzepin
Synonyms: HF 1927;Dibenzepin;4498-32-12;5-(2-dimethylaminoethyl)-11-methylbenzo[b][1,4]benzodiazepin-6-one;5-(2-dimethylaminoethyl)-11-methyl-benzo[b][1,4]benzodiazepin-6-one;5-Methyl-10-dimethylaminoethyl-10,11-dihydro-11-oxodibenzo[b,e][1,4]diazepine;5-Methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepine-11(10H)-one;10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one;10,11-Dihydro-5-methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepin-11-one;10,11-Dihydro-10-[2-(dimethylamino)ethyl]-5-methyl-5H-dibenzo[b,e][1,4]diazepin-11-one
CBNumber: CB21105957
Molecular Formula: C18H21N3O
Formula Weight: 295.38
MOL File: 4498-32-2.mol

More

Less

Dibenzepin Property

Melting point:: 116-117°C
Boiling point:: bp0.01 185°
Density: 1.1190 (rough estimate)
refractive index: 1.5855 (estimate)
storage temp.: Refrigerator
solubility: Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka: 8.25(at 25℃)
form: Solid
color: Light Beige to Brown
CAS DataBase Reference: 4498-32-2

More

Less

Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: D416920
Product name: Dibenzepin
Packaging: 50mg
Price: $1355
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21524
Product name: Dibenzepin
Packaging: 50mg
Price: $1529
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007971
Product name: DIBENZEPIN
Purity: 95.00%
Packaging: 50MG
Price: $1871.1
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21524
Product name: Dibenzepin
Packaging: 2mg
Price: $139.9
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21524
Product name: Dibenzepin
Packaging: 5mg
Price: $254.4
Updated: 2021/12/16

More

Less

Dibenzepin Chemical Properties,Usage,Production

Chemical Properties

Crystalline Solid

Originator

Noveril ,Wander,Switz.,1965

Uses

Antidepressant

Definition

ChEBI: 5-[2-(dimethylamino)ethyl]-11-methyl-6-benzo[b][1,4]benzodiazepinone is a dibenzodiazepine.

Manufacturing Process

4.48 grams of 5-methyl-11-hydroxy-5H-dibenzo[b,e][1,4]diazepine and 0.86
gram of sodium amide were boiled for one hour in 50 ml of absolute dioxane. After adding a concentrated benzenic solution of β-dimethylamino-ethyl chloride freshly prepared from 3.75 grams of the hydrochloride with concentrated sodium hydroxide solution, taking up in benzene and drying the solution with potash, the mixture was boiled for 16 hours under reflux, whereupon the reaction mixture was concentrated to dryness and the residue distributed between ether and water. By exhaustive extraction of the basic fractions with dilute acetic acid, precipitation with ammonia, taking up the base in ether and working up the ethereal solution, there was obtained 5.05 grams (85% of the theoretical) of 5-methyl-10-β-dimethylamino-ethyl-10,11- dihydro-11-oxo-5H-dibenzo[b,e][1,4]diazepine in the form of a viscous yellowish resin with the boiling point 185°C/0.01mm Hg. The base was crystallized from acetone-petroleum ether, MP 116°-117°C. Melting point of the monohydrochloride (from ethanol-ether) 234°-240°C.

Therapeutic Function

Psychostimulant

Dibenzepin Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Dibenzepin Suppliers

Canada 1 China 13 India 1 United Kingdom 1 Global 16

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 56902
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 17691182729 13992773979
Email: 1049@dideu.com
Country: China
ProdList: 7425
Advantage: 58

GIHI CHEMICALS CO.,LIMITED

Tel: +8618058761490
Email: info@gihichemicals.com
Country: China
ProdList: 49979
Advantage: 58

Shaanxi Didu New Materials Co. Ltd

Tel: +86-89586680 +86-13289823923
Email: 1026@dideu.com
Country: China
ProdList: 8670
Advantage: 58

Carbosynth

Tel: --
Fax: --
Email: sales@carbosynth.com
Country: United Kingdom
ProdList: 6005
Advantage: 58

4498-32-2, DibenzepinRelated Search:

Propyphenazone 2,2-DI-N-PROPYLACETAMIDE Gabapentin 5,10-DIHYDRO-DIBENZO[B,E][1,4]DIAZEPIN-11-ONE DIBENZEPINE HCL N-(2-aminophenyl)-N-methyl-N-phenylamine Dibenzepin

10-[2-(Dimethylamino)ethyl]-5,10-dihydro-5-methyl-11H-dibenzo[b,e][1,4]diazepin-11-one

5-Methyl-10-dimethylaminoethyl-10,11-dihydro-11-oxodibenzo[b,e][1,4]diazepine

HF 1927

Dibenzepin

10,11-Dihydro-10-[2-(dimethylamino)ethyl]-5-methyl-5H-dibenzo[b,e][1,4]diazepin-11-one

10,11-Dihydro-5-methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepin-11-one

5-Methyl-10-[2-(dimethylamino)ethyl]-5H-dibenzo[b,e][1,4]diazepine-11(10H)-one

4498-32-12

5-(2-dimethylaminoethyl)-11-methyl-benzo[b][1,4]benzodiazepin-6-one

5-(2-dimethylaminoethyl)-11-methylbenzo[b][1,4]benzodiazepin-6-one

11H-Dibenzo[b,e][1,4]diazepin-11-one, 10-[2-(dimethylamino)ethyl]-5,10-dihydro-5-methyl-

4498-32-2

Amines

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals