Propyphenazone

Product Name: Propyphenazone
CAS No.: 479-92-5
Chemical Name: Propyphenazone
Synonyms: Budirol;Causyth;Larodon;Cibalgina;Isopyrine;Isopropchin;Isopropyrine;Prophenazine;Propyphenazon;PROPYPHENAZONE
CBNumber: CB5193729
Molecular Formula: C14H18N2O
Formula Weight: 230.31
MOL File: 479-92-5.mol

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Propyphenazone Property

Melting point:: 102-105°C
Boiling point:: 372.3°C (rough estimate)
Density: 1.0371 (rough estimate)
refractive index: 1.5500 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
form: Solid
pka: 1.46±0.65(Predicted)
color: White to Off-White
Water Solubility: 743.6g/L(25.35 ºC)
Merck: 14,7871
BRN: 204533
Stability:: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference: 479-92-5(CAS DataBase Reference)
NIST Chemistry Reference: Propyphenazone(479-92-5)
EPA Substance Registry System: 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5)

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Safety

Hazard Codes: Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36/37/39
WGK Germany: 3
RTECS: CD2800000
HS Code: 2933.39.9200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR1389
Product name: Propyphenazone
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 1g
Price: $97.5
Updated: 2024/03/01

TCI Chemical

Product number: I0656
Product name: 4-Isopropylantipyrine
Purity: >98.0%(GC)
Packaging: 25g
Price: $64
Updated: 2024/03/01

Sigma-Aldrich

Product number: P3750000
Product name: Propyphenazone
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: p3750000
Price: $153
Updated: 2024/03/01

TRC

Product number: P838380
Product name: Propyphenazone
Packaging: 50g
Price: $875
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0007224
Product name: PROPYPHENAZONE
Purity: 95.00%
Packaging: 25G
Price: $950
Updated: 2021/12/16

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Propyphenazone Chemical Properties,Usage,Production

Description

This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.

Chemical Properties

solid

Uses

Analgesic; antipyretic; anti-inflammatory.

Definition

ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.

brand name

539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.

World Health Organization (WHO)

Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.

Clinical Use

Propyphenazone is a derivative of phenazone and has a similar analgesic and antipyretic action. It is used as a monocompound as well as in multi-ingredient preparations.

References

Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)

Propyphenazone Preparation Products And Raw materials

Raw materials

Preparation Products

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Propyphenazone Suppliers

Americas 1 Austria 1 Belgium 2 Brazil 1 Canada 1 China 130 Europe 3 France 2 Germany 11 India 37 Japan 4 Nepal 1 Poland 1 Slovakia 1 Slovenia 1 South Korea 2 Spain 2 Switzerland 3 United Kingdom 8 United States 27 Uruguay 1 Global 240

Zhejiang Haisen Pharmaceutical Co., Ltd.

Tel: 0579-86773082
Fax: 0579-86768666
Email: sale@haisenpharma.com
Country: China
ProdList: 7
Advantage: 58

Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd

Tel: 027-83850128 18207128853
Email: 3860188266@qq.com
Country: China
ProdList: 2047
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8836
Advantage: 52

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4554
Advantage: 62

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

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View Lastest Price from Propyphenazone manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Propyphenazone 479-92-5
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-10-29

Hebei Chuanghai Biotechnology Co,.LTD

Product: Propyphenazone 479-92-5
Price: US $1.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-15

Career Henan Chemical Co

Product: propyphenazone 479-92-5
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-25

479-92-5, PropyphenazoneRelated Search:

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1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3h-pyrazol-3-on

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PROPYPHENAZONE

ISOPROPYLPHENAZONE

1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl-3H-Pyrazol-3-one

1,2-dihydro-1,5-dimethyl-4-(isopropyl)-2-phenyl-pyrazol-3-one

1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one

1-phenyl-2,3-dimethyl-4-isopropyl-5-Pyrazolone

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3-Pyrazolin-5-one, 2,3-dimethyl-4-isopropyl-1-phenyl-

4-ISOPROPYL-2,3-DIMETHYL-1-PHENYL-5-PYRAZOLONE

2,3-Dimethyl-1-phenyl-4-isopropylpyrazolone

4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazoline-5-on

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3,3-Dimethyl-2-Methylene Norcamphone

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1,5-dimethyl-2-phenyl-4-propan-2-ylpyrazol-3-one

4-isopropyl-1,5-dimethyl-2-phenyl-pyrazol-3-one

Phentermine Solution, 100ppm

PROPYLPHENAZONE

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Propyphenazone (EDMF)

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Propyphenazone CRS

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