Propyphenazone
- Product Name
- Propyphenazone
- CAS No.
- 479-92-5
- Chemical Name
- Propyphenazone
- Synonyms
- Budirol;Causyth;Larodon;Cibalgina;Isopyrine;Isopropchin;Isopropyrine;Propyphenazon;PROPYPHENAZONE;(-)-Asparagine
- CBNumber
- CB5193729
- Molecular Formula
- C14H18N2O
- Formula Weight
- 230.31
- MOL File
- 479-92-5.mol
Propyphenazone Property
- Melting point:
- 102-105°C
- Boiling point:
- 372.3°C (rough estimate)
- Density
- 1.0371 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Slightly soluble in water, freely soluble in ethanol (96 per cent) and in methylene chloride.
- pka
- 1.46±0.65(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- 743.6g/L(25.35 ºC)
- Merck
- 14,7871
- BRN
- 204533
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- CAS DataBase Reference
- 479-92-5(CAS DataBase Reference)
- NIST Chemistry Reference
- Propyphenazone(479-92-5)
- EPA Substance Registry System
- 3H-Pyrazol-3-one, 1,2-dihydro-1,5-dimethyl-4-(1-methylethyl)-2-phenyl- (479-92-5)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- RTECS
- CD2800000
- HS Code
- 2933.39.9200
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- PHR1389
- Product name
- Propyphenazone
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 1g
- Price
- $97.5
- Updated
- 2024/03/01
- Product number
- I0656
- Product name
- 4-Isopropylantipyrine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $64
- Updated
- 2024/03/01
- Product number
- P3750000
- Product name
- Propyphenazone
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- p3750000
- Price
- $153
- Updated
- 2024/03/01
- Product number
- P838380
- Product name
- Propyphenazone
- Packaging
- 50g
- Price
- $875
- Updated
- 2021/12/16
- Product number
- API0007224
- Product name
- PROPYPHENAZONE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $950
- Updated
- 2021/12/16
Propyphenazone Chemical Properties,Usage,Production
Description
This uncharacterized alkaloid has been described by Hartsen as occurring in Iso_x0002_pyrum thalictroides L. No chemical or physical characteristics are known.
Chemical Properties
solid
Uses
Analgesic; antipyretic; anti-inflammatory.
Definition
ChEBI: A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.
brand name
539 grippe-dragees;Amipylo-n;Balpiren;Baukal;Caffalgina;Camoplex;Cantacin;Cerebrol;Daturmed;Degripol;Dentocaps a;Dim-antos;Dolibral;Dolo-mineuron;Dysmalgin;Ejcopyrin;Epizon;Escomen;Estesina;Fd 8;Febral;Finigripp;Grippocaps;Heaven;Infantex;Influvit;Isopronazon;Kavapyret;Kuronde;Lysadestat;Mamaslu;Milneuron;Myo-europan;Neuramin;Neuridal;Neuro-spondryl;Nodiras;Noric;Otobacid;Pfeil;Reomin;Retamex;Rheumanol;Rhinivict;Sanalgin-p;Saridon neu;Saridone;Sedospin;Servalgin;Sonotryl;Spalt;Spongamed;Stona;Synpyrin;Vivcet;Wauco-sin;Wecontrin.
World Health Organization (WHO)
Propyphenazone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1951 for the treatment of rheumatic disorders. As it is structurally related to aminophenazone it has been associated with severe blood dyscrasias. However, it cannot be transformed into potentially carcinogenic nitrosamines and has therefore been widely used as a replacement drug for aminophenazone. In certain countries, products containing propyphenazone have now been restricted in their indications, whereas in others they are still available, sometimes as over-the-counter preparations. See also WHO comment for aminophenazone.
Clinical Use
Propyphenazone is a derivative of phenazone and has a similar analgesic and antipyretic action. It is used as a monocompound as well as in multi-ingredient preparations.
References
Hartsen., J. Chem. Soc., 511 (1873) Mirande., Compt. rend., 168,316 (1919)
Propyphenazone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propyphenazone manufacturers
- Product
- Propyphenazone 479-92-5
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-10-29
- Product
- Propyphenazone 479-92-5
- Price
- US $1.90/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2024-08-15
- Product
- propyphenazone 479-92-5
- Price
- US $7.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2018-12-25