2-Methyl-4-trifluoromethylimidazole
- Product Name
- 2-Methyl-4-trifluoromethylimidazole
- CAS No.
- 33468-67-6
- Chemical Name
- 2-Methyl-4-trifluoromethylimidazole
- Synonyms
- 2-METHYL-4-TRIFLUOROMETHYLIMIDAZOLE;2-Methyl-5-(trifluoromethyl)-1H-imidazole;2-Methyl-4-(trifluoroMethyl)-2H-iMidazole;2-methyl-4-(trifluoromethyl)-1H-imidazole;1H-Imidazole, 2-methyl-4-(trifluoromethyl)-;1H-Imidazole, 2-methyl-5-(trifluoromethyl)-;2-Methyl-5-(trifluoromethyl)-1H-imidazole 95%;2-Methyl-4-trifluoromethyl-1H-imidazole
- CBNumber
- CB21120903
- Molecular Formula
- C5H5F3N2
- Formula Weight
- 150.1
- MOL File
- 33468-67-6.mol
2-Methyl-4-trifluoromethylimidazole Property
- Melting point:
- 179-180 °C
- Boiling point:
- 249 °C
- Density
- 1.355
- Flash point:
- 105 °C
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 10.84±0.10(Predicted)
- InChI
- InChI=1S/C5H5F3N2/c1-3-9-2-4(10-3)5(6,7)8/h2H,1H3,(H,9,10)
- InChIKey
- UTUSYSDVLOWRJA-UHFFFAOYSA-N
- SMILES
- C1(C)NC(C(F)(F)F)=CN=1
N-Bromosuccinimide Price
- Product number
- MNO000165
- Product name
- 2-Methyl-4-trifluoromethyl-1H-imidazole
- Packaging
- 1g
- Price
- $185
- Updated
- 2025/07/31
- Product number
- B486205
- Product name
- 2-Methyl-4-(trifluoromethyl)-1H-imidazole
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 064636
- Product name
- 2-Methyl-4-trifluoromethyl-1H-imidazole
- Purity
- 95%
- Packaging
- 5g
- Price
- $239
- Updated
- 2021/12/16
- Product number
- PC48292
- Product name
- 2-Methyl-5-(trifluoromethyl)-1H-imidazole
- Purity
- 95%
- Packaging
- 5g
- Price
- $260
- Updated
- 2021/12/16
- Product number
- 3H31-3-25
- Product name
- 2-Methyl-5-(trifluoromethyl)-1H-imidazole
- Purity
- 97%
- Packaging
- 1g
- Price
- $125
- Updated
- 2021/12/16
2-Methyl-4-trifluoromethylimidazole Chemical Properties,Usage,Production
Synthesis
75-07-0
91944-47-7
33468-67-6
General procedure for the synthesis of 2-methyl-4-trifluoromethylimidazole from acetaldehyde and trifluoromethanesulfonic acid: to a 10 mL sealed tube was added a mixture of acetaldehyde (296 μL, 5.29 mmol), 3,3,3-trifluoro-2-oxopropanal (Compound 16.1, 1.0 g, 7.9 mmol) and 25% ammonium hydroxide solution (0.8 mL) in methanol (5 mL) Solution. The reaction mixture was stirred at 0°C for 3 hours, followed by continued stirring at room temperature overnight. After completion of the reaction, the mixture was concentrated under reduced pressure and the residue was diluted with water (50 mL). The aqueous phase was extracted with ethyl acetate (3 x 20 mL), the organic phases were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography to give 430 mg (54% yield) of 2-methyl-4-trifluoromethylimidazole as a light yellow solid.
References
[1] Patent: WO2014/8197, 2014, A1. Location in patent: Page/Page column 89
[2] Patent: WO2015/95767, 2015, A1. Location in patent: Page/Page column 104
2-Methyl-4-trifluoromethylimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Methyl-4-trifluoromethylimidazole manufacturers
- Product
- 2-Methyl-4-trifluoromethylimidazole 33468-67-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-14
- Product
- 2-Methyl-4-trifluoromethylimidazole 33468-67-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98% HPLC
- Supply Ability
- 10 tons/month
- Release date
- 2020-01-09