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Sodium thioglycolate

Product Name
Sodium thioglycolate
CAS No.
367-51-1
Chemical Name
Sodium thioglycolate
Synonyms
THIOGLYCOLIC ACID SODIUM SALT;NATG;SODIUM THIOGLYCOLLATE;STG;Erhavit D;usafek-5199;Sodium thiog;Sodium thiogL;Natriumthioglykolat;SodiuM thioglycolat
CBNumber
CB2113072
Molecular Formula
C2H5NaO2S
Formula Weight
116.11
MOL File
367-51-1.mol
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Sodium thioglycolate Property

Melting point:
>300 °C (lit.)
bulk density
200kg/m3
vapor pressure 
<0.1 hPa (25 °C)
storage temp. 
-20°C
solubility 
609.1g/l
form 
solid
pka
3.82[at 20 ℃]
color 
White powder
Odor
Stench odour
PH Range
6.5 - 8 at 114 g/l at 25 °C
PH
6.7 (100g/l, H2O, 20℃)
Water Solubility 
soluble
Sensitive 
Air Sensitive & Hygroscopic
Merck 
14,8692
BRN 
4569109
Exposure limits
ACGIH: TWA 1 ppm (Skin)
LogP
-2.99 at 20℃
CAS DataBase Reference
367-51-1(CAS DataBase Reference)
EPA Substance Registry System
Sodium thioglycolate (367-51-1)
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Safety

Hazard Codes 
Xn
Risk Statements 
22-38-36/37/38
Safety Statements 
36-28-26
RIDADR 
2811
WGK Germany 
1
RTECS 
AI7700000
3-10-13-23
TSCA 
Yes
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29309070
Toxicity
LD50 i.p. in rats: 148 mg/kg, Freeman, Rosenthal, Fed. Proc. 11, 347 (1952)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H301Toxic if swalloed

H312Harmful in contact with skin

H317May cause an allergic skin reaction

Precautionary statements

P234Keep only in original container.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T0632
Product name
Sodium thioglycolate
Purity
≥96.5% (iodometric)
Packaging
25g
Price
$54.3
Updated
2024/03/01
Sigma-Aldrich
Product number
T0632
Product name
Sodium thioglycolate
Purity
≥96.5% (iodometric)
Packaging
100g
Price
$90.2
Updated
2024/03/01
Sigma-Aldrich
Product number
1.06691
Product name
Sodium thioglycolate
Purity
for microbiology
Packaging
500g
Price
$1050
Updated
2024/03/01
TCI Chemical
Product number
M0053
Product name
Sodium Thioglycolate
Purity
>93.0%(T)
Packaging
25g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
M0053
Product name
Sodium Thioglycolate
Purity
>93.0%(T)
Packaging
100g
Price
$72
Updated
2024/03/01
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Sodium thioglycolate Chemical Properties,Usage,Production

Chemical Properties

White solid

Uses

dipilatory, irritant, chelating agent

Uses

Sodium thioglycolate has been used:

  • as a growth supplement in enrichment media and to study its effect on Arcobacter
  • in influenza hemagglutinin formulation in order to reduce disulfide-mediated cross-linking and early potency loss
  • in electron microscopy

Uses

In cold-waving of hair; as depilatory; in bacteriology for the preparation of thioglycolate media; as analytical reagent, see Thioglycolic Acid.

Definition

The sodium salt of thioglycolic acid.

General Description

White powder with a slight odor. Used in cold-waving of hair and as a dipilatory.

Air & Water Reactions

Hygroscopic. Discolors on exposure to air. Water soluble.

Reactivity Profile

Sodium thioglycolate is hygroscopic and sensitive to air. Discolors if exposed to iron . May generate flammable and toxic hydrogen sulfide with strong reducing agents.

Hazard

Yields toxic hydrogen sulfide on decompo- sition, may be toxic by skin absorption.

Fire Hazard

Flash point data for Sodium thioglycolate are not available. Sodium thioglycolate is probably combustible.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Sodium thioglycolate is a commonly used reagent for bacteriological research to maintain reducing conditions in media. Thioglycolate can also protect enzymes against inactivation by maintaining protein thiol groups in the reduced state. Thioglycolate medium is frequently used in inflammation research to elicit a neutrophil and macrophage response in vivo.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. A human skin irritant. This material yields hydrogen sulfide on decomposition. A death has been attributed to the absorption of toxic decomposition products from the use of this material in a hair permanent-waving solution. When heated to decomposition it emits toxic fumes of SOx and Na2O. See also SULFIDES and MERCAPTANS.

Purification Methods

It crystallises from 60% EtOH (charcoal). It is hygroscopic.[Beilstein 3 IV 600.]

Sodium thioglycolate Preparation Products And Raw materials

Raw materials

Preparation Products

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Sodium thioglycolate Suppliers

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View Lastest Price from Sodium thioglycolate manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
Sodium thioglycolate 367-51-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-25
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Mercaptoacetic acid sodium salt 367-51-1
Price
US $100.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-04-24
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Sodium thioglycolate 367-51-1
Price
US $50.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/week
Release date
2024-04-24

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