Ammonium thioglycolate
- Product Name
- Ammonium thioglycolate
- CAS No.
- 5421-46-5
- Chemical Name
- Ammonium thioglycolate
- Synonyms
- ATG;usafmo-2;Perm salt;thiofacoa-50;Hair waving agent;(ca. 60% in Water);Ammoniumthioglykolat;Hair waving agent 95%;AMMONIUM THIOGLYCOLATE;AMMONIUM THIOGLYCOLLATE
- CBNumber
- CB5445341
- Molecular Formula
- C2H7NO2S
- Formula Weight
- 109.15
- MOL File
- 5421-46-5.mol
Ammonium thioglycolate Property
- Melting point:
- 139-139.5 °C
- Boiling point:
- 115℃[at 101 325 Pa]
- Density
- 1.22
- vapor pressure
- 0.001Pa at 25℃
- form
- Solution
- Specific Gravity
- 1.245 (25℃)
- color
- Clear colorless
- Odor
- strong skunk-like odor
- Water Solubility
- Miscible
- InChIKey
- JYAVWXRMOOCSOD-UHFFFAOYSA-N
- LogP
- -2.99 at 20℃
- CAS DataBase Reference
- 5421-46-5(CAS DataBase Reference)
- EPA Substance Registry System
- Acetic acid, 2-mercapto-, ammonium salt (1:1) (5421-46-5)
Safety
- Hazard Codes
- T
- Risk Statements
- 25-43
- Safety Statements
- 36/37-45-37-24
- RIDADR
- 2810
- WGK Germany
- 1
- RTECS
- AI7525000
- HazardClass
- 6.1(b)
- PackingGroup
- III
- HS Code
- 29309090
- Hazardous Substances Data
- 5421-46-5(Hazardous Substances Data)
- Toxicity
- LD50 ipr-rat: 165 mg/kg JPETAB 97,349,49
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H301Toxic if swalloed
H317May cause an allergic skin reaction
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 10010
- Product name
- Ammonium thioglycolate solution
- Purity
- ~60% in H2O
- Packaging
- 1l
- Price
- $84.9
- Updated
- 2024/03/01
- Product number
- A2217
- Product name
- Ammonium Thioglycolate (ca. 60% in Water)
- Packaging
- 25g
- Price
- $19
- Updated
- 2024/03/01
- Product number
- A2217
- Product name
- Ammonium Thioglycolate (ca. 60% in Water)
- Packaging
- 500g
- Price
- $35
- Updated
- 2024/03/01
- Product number
- A634080
- Product name
- AmmoniumThioglycolate
- Packaging
- 2.5g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- A634080
- Product name
- AmmoniumThioglycolate
- Packaging
- 10g
- Price
- $140
- Updated
- 2021/12/16
Ammonium thioglycolate Chemical Properties,Usage,Production
Description
Ammonium thioglycolate, also known as perm salt, is the chemical compound with the formula HSCH2CO2NH4. Being the salt of a weak acid and weak base, ammonium thioglycolic acid exists in solution as an equilibrium mixture of the salt itself as well as the free carboxylic acid thioglycolic acid (HSCH2CO2H) and ammonia : HSCH2COO- + NH4+ ? HSCH2COOH + NH3.
Chemical Properties
Clear colorless solution with characteristic odor
Uses
acts as a reducing agent in permanent-waving formulations for hair treatment and in shrink-resistant treatment of wool.
Uses
Ammonium thioglycolate is contained in permanent waves solutions and causes contact dermatitis in hairdressers.
Uses
Solutions of various strengths are used for hair waving and for hair removal.
Definition
ChEBI: Ammonium thioglycolate is an organic ammonium salt having thioglycolate(1-) as the counterion. Also known as perm salt, it has use in perming hair. It has a role as a reducing agent and an allergen. It contains a thioglycolate(1-).
General Description
Colorless to faint pink liquid with a repulsive, skunk-like odor.
Air & Water Reactions
Water soluble.
Reactivity Profile
Ammonium thioglycolate may be sensitive to heat. Ammonium thioglycolate is incompatible with acids.
Fire Hazard
Flash point data for Ammonium thioglycolate are not available. Ammonium thioglycolate is combustible.
Flammability and Explosibility
Not classified
Contact allergens
This substance is contained in “basic” permanent waves solutions and causes contact dermatitis in hairdressers.
Safety Profile
Poison by intravenous and intraperitoneal routes. An allergen; can cause contact dermatitis. Emits hydrogen sulfide. See also SULFIDES. When heated to decomposition it emits very toxic NOx, SOx, and NH3.
Chemical concepts related to perms
When discussing the chemistry of perms, one should consider two chemical facts. First is the thiol-disulfide equilibrium:
RSH + R'SSR' ? R'SH + RSSR'
where R and R' are organic substituents such as methyl (-CH3), ethyl (-C2H5), or -CH2COO-.
The thiol-disulfide exchange reaction is accelerated by bases such as ammonia, because the base generates some thiolate anion (RS- ), which attacks the disulfide. Thus the ammonia plays multiple roles (and more, see below) in this application.
The second chemical fact is that polar molecules are less volatile than nonpolar ones. So the glycolate substituent makes the thiol nonvolatile and hence non-odorous. An added advantage is that the glycolate confers some solubility in water. One could almost certainly use HSCH3 and ammonia to give a perm, but there would be serious olfactory consequences.
The actual chemistry of perms
A solution containing ammonium thioglycolate contains a lot of free ammonia, which swells hair, rendering it permeable. The thioglycolic acid in the perm solution reduces the disulfide cystine bonds in the cortex of the hair. In a sense, the thioglycolate removes crosslinks. After washing, the hair is treated with a mild solution of hydrogen peroxide, which oxidizes the cysteines back to cystine. These new chemical bonds impart the structural rigidity necessary for a successful perm. The rigidification process is akin to the vulcanization of rubber, where commonly polysulfide linkages are used to crosslink the polymer chains. However, not as many disulfide bonds are reformed as there were before the permanent. As a result, the hair is weaker than before the permanent was applied and repeated applications over the same spot may eventually cause strand breakage.
Ammonium thioglycolate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ammonium thioglycolate manufacturers
- Product
- Ammonium thioglycolate 5421-46-5
- Price
- US $50.00/kg
- Min. Order
- 1kg
- Purity
- 60%
- Supply Ability
- 20ton
- Release date
- 2024-04-22
- Product
- ?Ammonium thioglycolate 5421-46-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 40% 60% 70%
- Supply Ability
- 200MT/Month
- Release date
- 2024-04-03
- Product
- Ammonium thioglycolate 5421-46-5
- Price
- US $100.00/drum
- Min. Order
- 1drum
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2023-08-28