Cyromazine

Description References

Product Name: Cyromazine
CAS No.: 66215-27-8
Chemical Name: Cyromazine
Synonyms: CIROMAZIN;CYROMAZIN;N2-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE;ARMOR;neoprex;TRIGARD;NEPOREX;Neoprox;cga72662;ARMOR(R)
CBNumber: CB2120418
Molecular Formula: C6H10N6
Formula Weight: 166.18
MOL File: 66215-27-8.mol

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Cyromazine Property

Melting point:: 223-227 °C (lit.)
Boiling point:: 284.39°C (rough estimate)
Density: 1.3196 (rough estimate)
vapor pressure: 4.5 x l0^-7 Pa (25 °C)
refractive index: 1.8300 (estimate)
Flash point:: 100 °C
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 5.2 (base)
Water Solubility: 13 g l^-1 (pH 7.1,25 °C)
form: Solid
color: White to Off-White
Merck: 14,2775
BRN: 882879
Stability:: Hygroscopic
InChIKey: LVQDKIWDGQRHTE-UHFFFAOYSA-N
LogP: -0.061 at 25℃
CAS DataBase Reference: 66215-27-8(CAS DataBase Reference)
NIST Chemistry Reference: Cyromazine(66215-27-8)
EPA Substance Registry System: Cyromazine (66215-27-8)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: UN3077 (solid)
WGK Germany: 2
RTECS: XZ1056500
HS Code: 29336990
Hazardous Substances Data: 66215-27-8(Hazardous Substances Data)
Toxicity: LC50 (96-hour) for rainbow trout and carp >100 mg/L and bluegill sunfish >90 mg/L (Hartley and Kidd, 1987); acute oral LD50 for rats 3,387 mg/kg (Hartley and Kidd, 1987)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2899
Product name: Cyromazine
Purity: pharmaceutical secondary standard, certified reference material
Packaging: 500MG
Price: $172
Updated: 2024/03/01

Sigma-Aldrich

Product number: 45414
Product name: Cyromazin
Purity: PESTANAL , analytical standard
Packaging: 50mg
Price: $90.1
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1161203
Product name: Cyromazin
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 200mg
Price: $457
Updated: 2024/03/01

TCI Chemical

Product number: C2366
Product name: Cyromazine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: C2366
Product name: Cyromazine
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $39
Updated: 2024/03/01

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Cyromazine Chemical Properties,Usage,Production

Description

Cyromazine is a triazine insect growth regulator that can be used as an insecticide and an acarcide. It is a kind of cyclopropylderivative of melamine, and also belongs to the family of aminotriazines which are compound consisting of an amino group attached to a triazine ring. It has specific activity against dipterous larvae, and has been approved by FDA for being applied to livestock. It is not a kind of cholinesterase inhibitor, and taking effect through affecting the nervous system of the immature larval stage of the insects.

References

https://pubchem.ncbi.nlm.nih.gov/compound/cyromazine#section=Top
https://en.wikipedia.org/wiki/Cyromazine
http://pmep.cce.cornell.edu/profiles/insect-mite/cadusafos-cyromazine/cyromazine/insect-prof-cyromazine.html

Chemical Properties

White crystalline powder. The solubility in water is 11,000 mg/L at 20°C and pH 7.5, and the hydrolysis is not obvious at pH 5-9.

Uses

Cypromazine is a high-efficiency and low-toxicity insecticide. It is mainly used to control leafminer pests, has a good control effect on Liriomyza, and can also be used to control flies.

Application

Cyromazine is an insect growth regulator, used to control fly larvae in livestock and poultry manure. It can be fed directly to livestock or applied directly to fly breeding sites. Cyromazine also exhibits systemic activity and is used as a foliar spray to control leaf miners in vegetables, potatoes, etc., and on mushrooms.

Definition

ChEBI: Cyromazine is a triamino-1,3,5-triazine. It has a role as a triazine insecticide and a mouse metabolite.

Preparation

Cyromazine is prepared by the reaction of cyanuric chloride and cyclopropylamine to obtain 2-Cyclopropylamino-4,6-dichloro-triazepine, and then reacts with ammonia to obtain 2-Cyclopropylamino-4-chloro-6-aminostriazepine, and then reacting with ammonia to produce.

General Description

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine, also known as cyromazine, is an insect growth regulator(IGR) that is commonly used as an insecticide. It undergoes metabolism in plants and animals to form melamine. Surface-enhanced Raman scattering (SERS) spectroscopic study indicates that it interacts with the surface of silver colloid through the lone pair on nitrogen.

Flammability and Explosibility

Not classified

Agricultural Uses

Insecticide (insect growth regulator): As an insect growth regulator, cyromazine is fed to caged poultry and is passed through the chicken, leaving a residue in the manure. The chemical controls the growth of the fly larvae developing in the manure. Used as a foliar spray to control leaf miners in vegetables, mushrooms, potatoes and ornamentals and to control flies on animals.

Trade name

ARMOR®; CITATION; CGA-72662®; LARVADEX®; PATRON®; TRIGARD®; VETRAZIN®

Environmental Fate

Chemical/Physical. Cyromazine will react with mineral acids (e.g., hydrochloric acid, sulfuric acid) forming water-soluble salts

Metabolic pathway

Information presented in this summary is abstracted from the data evaluation published by the Pesticide Safety Directorate (PSD, 1993). The major degradation pathway of cyromazine involves the N-dealkylation of the cyclopropyl moiety to yield melamine. Both cyromazine and melamine are quite stable to biotransformation. Deamination and the formation of N-methylcyromazine were observed as minor pathways.

Degradation

Cyromazine (1) is stable to hydrolysis at pH 5, 7 and 9 and 70 °C for up to 28 days. No degradation of cyromazine was observed when irradiated under mercury vapour lamp (>290 nm) at 25 °C for up to 168 hours.

Cyromazine Preparation Products And Raw materials

Raw materials

Cyclopropylamine Ammonium hydroxide 4-Chlorobenzaldehyde Nitrobenzene Cyanuric chloride

Preparation Products

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Cyromazine Suppliers

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View Lastest Price from Cyromazine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Cyromazine 66215-27-8
Price: US $120.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10ton
Release date: 2024-05-21

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Cyromazine 66215-27-8
Price: US $0.00/kg
Min. Order: 25kg
Purity: ≥98.0%
Supply Ability: 10tons
Release date: 2024-04-26

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Cyromazine 66215-27-8
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%-102%; USP
Supply Ability: 1000 KG
Release date: 2021-06-04

66215-27-8, CyromazineRelated Search:

1,3,5-Triazine acepromazine IMIPRAMINE DIOXOPROMETHAZINE HCL Imipramine hydrochloride Cyclopropylamine Melamine DIOXOPROMETHAZINE N-CYCLOPROPYLMETHYLAMINE Cyromazine Cyromazine 8.9% WN Cyromazine suspension Cyromazine 75% WP Chlorpyrifos+Cyromazine,W.P.(25%) Cyromazine+Monosultap,S.P. CYROMAZINE SOLUTION 100UG/ML IN ACETONE 1ML CYROMAZINE 98.0% MIN CYROMAZINE SOLUTION 100UG/ML IN ACETONITRILE 1ML

Vetrazin【pesticide】

Cyromazine, 2-Cyclopropylamino-4,6-diamino-s-triazine

N-Cyclopropyl

5-triazine-2,4,6-triamine,n-cyclopropyl-3

ai3-52713

cga72662

neoprex

Cyromazine (200 mg)

2-N-cyclopropyl-1,3,5-triazine-2,4,6-triaMine

Cyromazine 500mg [66215-27-8]

N2-Cyclopropyl-

2,4-Diamino-6-(cyclopropylamino)-1,3,5-triazine N2-Cyclopropylmelamine

CyroMazin solution

CyroMazine Pure Raw Material

1,3,5-Triazine-2,4,6-triamine, N2-cyclopropyl-

N-Cyclopropyl-2,4,6-triamino-1,3,5-triazine 97%

Shiner it triazine

Cyromazine 0.2

ARMOR

ARMOR(R)

cyclopropyl-1,3,5-triazine-2,4,6-triamine

Cyclopropylmelamine

CYPROMAZINE

CYROMAZIN

CYROMAZINE

Diamino-6-(cyclopropylamino)-s-triazine

LARVADEX

VETRAZIN

VETRAZIN(R)

TRIGARD

TRIGARD(R)

2-cyclopropylamino-4,6-diamino-s-triazine

oms-2014

NEPOREX

NEPOREX(R)

N-CYCLOPROPYL-1,3,5-TRIAZIN-2,4,6-TRIAMINE

N-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE

N-CYCLOPROPY-1,3,5-TRIAZIN-2,4,6-TRIAMINE

N2-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE

1,3,5-Triazine-2,4,6-triamine, N-cyclopropyl-

cyromazine (bsi,iso,ansi)

CYROMAZINE(N-CYCLOPROPYL-1,3,5-TRIAZINE-2,4,6-TRIAMINE)

CIROMAZIN

Cyromazine (N-clopropyl-1,3,5-triazine-2,4,6-triamine)

N-CYCLOPROPYL-2,4,6-TRIAMINO-1,3,5-TRIAZIN E, 97%

CYROMAZINE, 500MG, NEAT

CYROMAZIN PESTANAL (N-CYCLOPROPYL- 1,3,5

CYROMAZIN (N-CYCLOPROPYL- 1,3,5-TRIAZINE-2,4,6-TRIAMINE)

N-Cyclopropyl-1,3,5-triazin-2,4,6-triamine, Cyromazin

Cyromazine dissoluble liquid

Cyromazine W.P.

Betrazin

Neoprox

Vetrazine

Cyromazine Solution, 1000ppm

2-N-cyclopropyl-1,3,5-triazine-2,4,6-tria

Cyromazine 66215-27-8

Cyromazine Solution in Methanol