ACIFRAN

Product Name: ACIFRAN
CAS No.: 72420-38-3
Chemical Name: ACIFRAN
Synonyms: ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
CBNumber: CB2121167
Molecular Formula: C12H10O4
Formula Weight: 218.21
MOL File: 72420-38-3.mol

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ACIFRAN Property

Melting point:: 176°
Boiling point:: 378.4±42.0 °C(Predicted)
Density: 1.343±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: Soluble in DMSO > 10 mM
form: Powder
pka: 2.25±0.40(Predicted)
color: Off-white to light yellow

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Safety

Toxicity: LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1762
Product name: Acifran
Purity: ≥99%(HPLC)
Packaging: 10
Price: $152
Updated: 2021/12/16

Tocris

Product number: 1762
Product name: Acifran
Purity: ≥99%(HPLC)
Packaging: 50
Price: $622
Updated: 2021/12/16

TRC

Product number: A795258
Product name: Acifran
Packaging: 5mg
Price: $360
Updated: 2021/12/16

Usbiological

Product number: 254534
Product name: Acifran
Packaging: 10mg
Price: $409
Updated: 2021/12/16

ApexBio Technology

Product number: B6848
Product name: Acifran
Packaging: 10mg
Price: $234
Updated: 2021/12/16

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ACIFRAN Chemical Properties,Usage,Production

Uses

Antihyperlipopro-teinemic.

Uses

Acifran is a nicotinic acid receptor agonist.

brand name

Reductol (Wyeth-Ayerst).

Biological Activity

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

storage

Store at +4°C

ACIFRAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ACIFRAN Suppliers

China 24 Germany 2 United Kingdom 3 United States 8 USA 1 Global 38

3B Pharmachem (Wuhan) International Co.,Ltd.

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Xiamen Huijia Biological Technology Co., Ltd.

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Shanghai Yuda Industrial Co., Ltd.

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Shanghai Chaoyan Biotechnology Co., Ltd.

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Shanghai Haoyang Biological Technology Co., Ltd.

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Debye Scientific Corporation

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Lanospharma Laboratories Co.,Ltd

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72420-38-3, ACIFRANRelated Search:

Axitinib 4,5-DIHYDRO-2-METHYLFURAN 4-OXO-2-HEXENAL TERT-BUTYL VINYL ETHER ACIFRAN TERT-BUTOXY ACETIC ACID 2,3-Dihydrofuran 2,5-Dimethyl-3(2H)-furanone

ay25712

ACIFRAN

4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID

(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid

4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid

Acifranum

4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci

5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid

2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-

72420-38-3

Miscellaneous Compounds