ChemicalBook > CAS DataBase List > ACIFRAN
ACIFRAN
- Product Name
- ACIFRAN
- CAS No.
- 72420-38-3
- Chemical Name
- ACIFRAN
- Synonyms
- ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
- CBNumber
- CB2121167
- Molecular Formula
- C12H10O4
- Formula Weight
- 218.21
- MOL File
- 72420-38-3.mol
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ACIFRAN Property
- Melting point:
- 176°
- Boiling point:
- 378.4±42.0 °C(Predicted)
- Density
- 1.343±0.06 g/cm3(Predicted)
- storage temp.
- Store at +4°C
- solubility
- Soluble in DMSO > 10 mM
- form
- Powder
- pka
- 2.25±0.40(Predicted)
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Safety
- Toxicity
- LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)
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N-Bromosuccinimide Price
Tocris
- Product number
- 1762
- Product name
- Acifran
- Purity
- ≥99%(HPLC)
- Packaging
- 10
- Price
- $152
- Updated
- 2021/12/16
Tocris
- Product number
- 1762
- Product name
- Acifran
- Purity
- ≥99%(HPLC)
- Packaging
- 50
- Price
- $622
- Updated
- 2021/12/16
TRC
- Product number
- A795258
- Product name
- Acifran
- Packaging
- 5mg
- Price
- $360
- Updated
- 2021/12/16
Usbiological
- Product number
- 254534
- Product name
- Acifran
- Packaging
- 10mg
- Price
- $409
- Updated
- 2021/12/16
ApexBio Technology
- Product number
- B6848
- Product name
- Acifran
- Packaging
- 10mg
- Price
- $234
- Updated
- 2021/12/16
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ACIFRAN Chemical Properties,Usage,Production
Uses
Antihyperlipopro-teinemic.
Uses
Acifran is a nicotinic acid receptor agonist.
brand name
Reductol (Wyeth-Ayerst).
Biological Activity
Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.
storage
Store at +4°C
ACIFRAN Preparation Products And Raw materials
Raw materials
Preparation Products
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ACIFRAN Suppliers
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