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ACIFRAN

Product Name
ACIFRAN
CAS No.
72420-38-3
Chemical Name
ACIFRAN
Synonyms
ACIFRAN;ay25712;Acifranum;4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci;4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid;4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID;5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid;2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-;(R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
CBNumber
CB2121167
Molecular Formula
C12H10O4
Formula Weight
218.21
MOL File
72420-38-3.mol
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ACIFRAN Property

Melting point:
176°
Boiling point:
378.4±42.0 °C(Predicted)
Density 
1.343±0.06 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
Soluble in DMSO > 10 mM
form 
Powder
pka
2.25±0.40(Predicted)
color 
Off-white to light yellow
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Safety

Toxicity
LD50 orally in rats: 3 g/kg (Jirkovsky, 1982)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1762
Product name
Acifran
Purity
≥99%(HPLC)
Packaging
10
Price
$152
Updated
2021/12/16
Tocris
Product number
1762
Product name
Acifran
Purity
≥99%(HPLC)
Packaging
50
Price
$622
Updated
2021/12/16
TRC
Product number
A795258
Product name
Acifran
Packaging
5mg
Price
$360
Updated
2021/12/16
Usbiological
Product number
254534
Product name
Acifran
Packaging
10mg
Price
$409
Updated
2021/12/16
ApexBio Technology
Product number
B6848
Product name
Acifran
Packaging
10mg
Price
$234
Updated
2021/12/16
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ACIFRAN Chemical Properties,Usage,Production

Uses

Antihyperlipopro-teinemic.

Uses

Acifran is a nicotinic acid receptor agonist.

brand name

Reductol (Wyeth-Ayerst).

Biological Activity

Hypolipidaemic agent; more potent than nicotinic acid and clofibrate. Full and potent agonist at the human orphan GPCR HM74A/GPR109A and GPR109B (EC 50 values are 1.3? and 4.2 μ M respectively). In vivo, reduces serum triglycerides and circulating LDL-cholesterol without affecting liver weight or liver enzymes.

storage

Store at +4°C

ACIFRAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ACIFRAN Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai Rechem science Co., Ltd.
Tel
21-31433387 15618786686
Fax
QQ:1369748377
Email
sales@rechemscience.com
Country
China
ProdList
2991
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32165
Advantage
58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
0519-85788828 13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3600
Advantage
58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24990
Advantage
58
Beijing Biocreative Technology Co., Ltd.
Tel
15522676233
Email
3007606172@qq.com
Country
China
ProdList
1248
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
Advantage
58
Shanghai Easy CDMO Co.,Ltd
Tel
021-61734564
Email
August@easycdmo.com
Country
China
ProdList
10030
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58

72420-38-3, ACIFRANRelated Search:


  • ay25712
  • ACIFRAN
  • 4,5-DIHYDRO-5-METHYL-4-OXO-5-PHENYL-2-FURANCARBOXYLIC ACID
  • (R,S)-4,5-Dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylic acid
  • 4,5-Dihydro-5-methyl-4-oxo-5-phenylfuran-2-carboxylic acid
  • Acifranum
  • 4,5-dihydro-5-methyl-4-oxo-5-phenyl-2-furancarboxylicaci
  • 5-Methyl-4-oxo-5-phenyl-4,5-dihydro-furan-2-carboxylic acid
  • 2-Furancarboxylic acid, 4,5-dihydro-5-methyl-4-oxo-5-phenyl-
  • 72420-38-3
  • Miscellaneous Compounds