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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-

Product Name
Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
CAS No.
333357-56-5
Chemical Name
Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
Synonyms
WAY-299838;HIF-1 inhibitor-4;HIF-1 inhibitor-4, 10 mM in DMSO;N-(4-Iodophenyl)-4-(morpholinomethyl)benzamide;Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)-
CBNumber
CB212123692
Molecular Formula
C18H19IN2O2
Formula Weight
422.26
MOL File
333357-56-5.mol
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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Property

Boiling point:
435.4±45.0 °C(Predicted)
Density 
1.576±0.06 g/cm3(Predicted)
pka
12.90±0.70(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Chemical Properties,Usage,Production

Uses

HIF-1 inhibitor-4 is a HIF-1 inhibitor (IC50: 560 nM). HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level[1].

References

[1] Nagao S, et al. Synthesis and structure-activity relationships of novel, potent, orally active hypoxia-inducible factor-1 inhibitors. Bioorg Med Chem. 2014 Oct 1;22(19):5513-29. DOI:10.1016/j.bmc.2014.07.020

Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzamide, N-(4-iodophenyl)-4-(4-morpholinylmethyl)- Suppliers

TargetMol Chemicals Inc.
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