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3-Bromo-2-chloro-5-(trifluoromethyl)pyridine

Product Name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
CAS No.
71701-92-3
Chemical Name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Synonyms
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine;Pyridine, 3-bromo-2-chloro-5-(trifluoromethyl)-;5-Bromo-6-chloro-alpha,alpha,alpha-trifluoro-3-picoline;3-Bromo-2-chloro-5-(trifluoromethyl)pyridine ISO 9001:2015 REACH
CBNumber
CB21261800
Molecular Formula
C6H2BrClF3N
Formula Weight
260.44
MOL File
71701-92-3.mol
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3-Bromo-2-chloro-5-(trifluoromethyl)pyridine Property

Melting point:
28-32℃
Boiling point:
210.5±35.0 °C(Predicted)
Density 
1.804±0.06 g/cm3(Predicted)
Flash point:
98°(208°F)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
pka
-3.34±0.10(Predicted)
form 
Solid
color 
Pale yellow to pale brown
CAS DataBase Reference
71701-92-3
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Safety

Hazard Codes 
Xi,T
Risk Statements 
25-36/37/38
Safety Statements 
7/9-22-24/25-26-36/37-38-45-51
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
HazardClass 
IRRITANT
HazardClass 
6.1
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
728748
Product name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Purity
97%
Packaging
5g
Price
$81.1
Updated
2023/06/20
TRC
Product number
B690893
Product name
3-Bromo-2-chloro-5-trifluoromethylpyridine
Packaging
500mg
Price
$65
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B11808
Product name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Purity
95%
Packaging
1g
Price
$5
Updated
2021/12/16
Apolloscientific
Product number
PC3352
Product name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
Matrix Scientific
Product number
031271
Product name
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
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3-Bromo-2-chloro-5-(trifluoromethyl)pyridine Chemical Properties,Usage,Production

Synthesis

A mixture of 3-bromo-5-(trifluoromethyl)pyridin-2-ol (37.75g, 0.16 mol) and phosphorus(lll) oxychloride (POCI3; 75 mL) is stirred at 1000C for 5 hours. After cooling to room temperature, the mixture is poured into ice-water and extracted with CH2CI2 twice. The combined organic layer is washed with NaHCO3 aq., brine, dried over MgSO4, filtered, and concentrated in vacuo. The crude mixture is purified by flash column chromatography to give 3-bromo-2-chloro-5-trifluoromethylpyridine (31.90 g, 79 % yield) as a white solid.

References

[1] Patent: WO2007/73934, 2007, A1. Location in patent: Page/Page column 75
[2] Patent: WO2008/58961, 2008, A1. Location in patent: Page/Page column 44; 45
[3] Patent: WO2008/58967, 2008, A1. Location in patent: Page/Page column 43; 44

3-Bromo-2-chloro-5-(trifluoromethyl)pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Bromo-2-chloro-5-(trifluoromethyl)pyridine Suppliers

INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
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View Lastest Price from 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine 71701-92-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-06-03
Henan Fengda Chemical Co., Ltd
Product
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine 71701-92-3
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Dideu Industries Group Limited
Product
3-Bromo-2-chloro-5-(trifluoromethyl)pyridine 71701-92-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-08-25

71701-92-3, 3-Bromo-2-chloro-5-(trifluoromethyl)pyridineRelated Search:


  • 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine
  • 5-Bromo-6-chloro-alpha,alpha,alpha-trifluoro-3-picoline
  • Pyridine, 3-bromo-2-chloro-5-(trifluoromethyl)-
  • 3-Bromo-2-chloro-5-(trifluoromethyl)pyridine ISO 9001:2015 REACH
  • 71701-92-3
  • 71707-92-3
  • Fluorine series
  • blocks
  • Bromides
  • FluoroCompounds
  • Pyridines