2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Product Name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- CAS No.
- 75806-84-7
- Chemical Name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Synonyms
- 2-Bromo-3-chL;BUTTPARK 153\33-66;2-Bromo-3-chloro-5-(trifluorom;2-BROMO-3-CHLORO-5-(TRIFLUOROMETHYL)PYRI;2-bromo-3-chloro-5-(triluoromethyl)pyridine;2-BROMO-3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;Pyridine, 2-bromo-3-chloro-5-(trifluoromethyl)-;2-Bromo-3-chloro-5-(trifluoromethyl)pyridine97%;2-Bromo-3-chloro-5-(trifluoromethyl)pyridine 97%;2--3--5- threebroMinechlorinefluorineMethyl pyridine
- CBNumber
- CB9120189
- Molecular Formula
- C6H2BrClF3N
- Formula Weight
- 260.44
- MOL File
- 75806-84-7.mol
2-Bromo-3-chloro-5-(trifluoromethyl)pyridine Property
- Boiling point:
- 88 °C
- Density
- 1.83
- refractive index
- 1.4990 to 1.5030
- Flash point:
- 91°
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- clear liquid
- pka
- -3.92±0.20(Predicted)
- color
- Light yellow to Yellow to Orange
- InChI
- InChI=1S/C6H2BrClF3N/c7-5-4(8)1-3(2-12-5)6(9,10)11/h1-2H
- InChIKey
- SMTKGMYGLYWNDL-UHFFFAOYSA-N
- SMILES
- C1(Br)=NC=C(C(F)(F)F)C=C1Cl
- CAS DataBase Reference
- 75806-84-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38-36/38
- Safety Statements
- 26-36-37/39-37
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B4603
- Product name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Purity
- >96.0%(GC)
- Packaging
- 1g
- Price
- $37
- Updated
- 2025/07/31
- Product number
- B4603
- Product name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Purity
- >96.0%(GC)
- Packaging
- 5g
- Price
- $121
- Updated
- 2025/07/31
- Product number
- B690888
- Product name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B690888
- Product name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 001622
- Product name
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $73
- Updated
- 2021/12/16
2-Bromo-3-chloro-5-(trifluoromethyl)pyridine Chemical Properties,Usage,Production
Synthesis
76041-71-9
75806-84-7
General procedure for the synthesis of 2-bromo-3-chloro-5-(trifluoromethyl)pyridine from 3-chloro-2-hydroxy-5-(trifluoromethyl)pyridine: 3-chloro-5-(trifluoromethyl)-2-hydroxypyridine (17.1 g, 0.087 mol) was added to 150 mL of tribromophosphorus oxide and heated to 150 °C for 6 hours. After the reaction was completed, it was cooled to room temperature. The reaction mixture was slowly and carefully added to ice water at -5 to 0 °C and stirred vigorously at 200 rpm for 1 hour. The resulting mixture was extracted three times with dichloromethane. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated to give the crude product. The crude product was purified by silica gel column chromatography using dichloromethane-methanol (100:1 to 20:1, v/v) as eluent to give 13.1 g of 2-bromo-3-chloro-5-(trifluoromethyl)pyridine (0.05 mol) in 58% yield.
References
[1] Patent: CN102875453, 2016, B. Location in patent: Paragraph 0026
2-Bromo-3-chloro-5-(trifluoromethyl)pyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine manufacturers
- Product
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine 75806-84-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-06-03
- Product
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine 75806-84-7
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyridine 75806-84-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-22