4-CYANO-2,6-DIFLUOROBENZOIC ACID
- Product Name
- 4-CYANO-2,6-DIFLUOROBENZOIC ACID
- CAS No.
- 181073-82-5
- Chemical Name
- 4-CYANO-2,6-DIFLUOROBENZOIC ACID
- Synonyms
- Benzoic acid, 4-cyano-2,6-difluoro-;4-Cyano-2,6-difluorobenzoic acid 95%
- CBNumber
- CB21264058
- Molecular Formula
- C8H3F2NO2
- Formula Weight
- 183.11
- MOL File
- 181073-82-5.mol
4-CYANO-2,6-DIFLUOROBENZOIC ACID Property
- Boiling point:
- 303.9±42.0 °C(Predicted)
- Density
- 1.51±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 1.68±0.10(Predicted)
- Appearance
- White to light yellow Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- B427988
- Product name
- 4-cyano-2,6-difluorobenzoicacid
- Packaging
- 100mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- B427988
- Product name
- 4-cyano-2,6-difluorobenzoicacid
- Packaging
- 500mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- FC105068
- Product name
- 4-cyano-2,6-difluorobenzoic Acid
- Packaging
- 500mg
- Price
- $400
- Updated
- 2021/12/16
- Product number
- FC105068
- Product name
- 4-cyano-2,6-difluorobenzoic Acid
- Packaging
- 1g
- Price
- $600
- Updated
- 2021/12/16
- Product number
- FC105068
- Product name
- 4-cyano-2,6-difluorobenzoic Acid
- Packaging
- 250mg
- Price
- $250
- Updated
- 2021/12/16
4-CYANO-2,6-DIFLUOROBENZOIC ACID Chemical Properties,Usage,Production
Synthesis
467442-15-5
181073-82-5
Step b: Synthesis of 4-cyano-2,6-difluorobenzoic acid To a solution of 3,5-difluoro-4-formylbenzonitrile (0.2 g, 1.1 mmol) in dimethyl sulfoxide (10 mL) was added an aqueous solution of potassium dihydrogen phosphate (0.41 g, 2.9 mmol, dissolved in 0.4 mL of water) and sodium chlorite (0.216 g, 2.3 mmol, dissolved in 4 mL of water) in sequence. The reaction was carried out at room temperature with stirring for about 1 hour. After completion of the reaction, the reaction mixture was diluted with water (100 mL) and the aqueous phase was extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated to give 4-cyano-2,6-difluorobenzoic acid (200 mg, 91.32% yield) as a white solid. 1H NMR (400 MHz, DMSO-d6): δ 7.95 (d, J = 7.53 Hz, 2H).
References
[1] Patent: WO2012/160464, 2012, A1. Location in patent: Page/Page column 69
[2] Patent: US2014/155398, 2014, A1. Location in patent: Paragraph 0415
[3] Patent: WO2011/28685, 2011, A1. Location in patent: Page/Page column 77; 78
4-CYANO-2,6-DIFLUOROBENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-CYANO-2,6-DIFLUOROBENZOIC ACID manufacturers
- Product
- 4-Cyano-2,6-difluorobenzoic acid 181073-82-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 5mg
- Purity
- 99%HPLC
- Supply Ability
- 2000tons
- Release date
- 2020-01-07