ChemicalBook > CAS DataBase List > 4-CYANO-2,6-DIFLUOROBENZOIC ACID

4-CYANO-2,6-DIFLUOROBENZOIC ACID

Product Name: 4-CYANO-2,6-DIFLUOROBENZOIC ACID
CAS No.: 181073-82-5
Chemical Name: 4-CYANO-2,6-DIFLUOROBENZOIC ACID
Synonyms: Benzoic acid, 4-cyano-2,6-difluoro-;4-Cyano-2,6-difluorobenzoic acid 95%
CBNumber: CB21264058
Molecular Formula: C8H3F2NO2
Formula Weight: 183.11
MOL File: 181073-82-5.mol

Less

4-CYANO-2,6-DIFLUOROBENZOIC ACID Property

Boiling point:: 303.9±42.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 1.68±0.10(Predicted)
Appearance: White to light yellow Solid

Less

Safety

HS Code: 2926907090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

Less

N-Bromosuccinimide Price

TRC

Product number: B427988
Product name: 4-cyano-2,6-difluorobenzoicacid
Packaging: 100mg
Price: $90
Updated: 2021/12/16

TRC

Product number: B427988
Product name: 4-cyano-2,6-difluorobenzoicacid
Packaging: 500mg
Price: $350
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC105068
Product name: 4-cyano-2,6-difluorobenzoic Acid
Packaging: 50mg
Price: $100
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4637-3-2R
Product name: 4-Cyano-2,6-difluorobenzoic acid
Packaging: 100mg
Price: $119
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC105068
Product name: 4-cyano-2,6-difluorobenzoic Acid
Packaging: 100mg
Price: $160
Updated: 2021/12/16

Less

4-CYANO-2,6-DIFLUOROBENZOIC ACID Chemical Properties,Usage,Production

Synthesis

467442-15-5

181073-82-5

Step b: Synthesis of 4-cyano-2,6-difluorobenzoic acid To a solution of 3,5-difluoro-4-formylbenzonitrile (0.2 g, 1.1 mmol) in dimethyl sulfoxide (10 mL) was added an aqueous solution of potassium dihydrogen phosphate (0.41 g, 2.9 mmol, dissolved in 0.4 mL of water) and sodium chlorite (0.216 g, 2.3 mmol, dissolved in 4 mL of water) in sequence. The reaction was carried out at room temperature with stirring for about 1 hour. After completion of the reaction, the reaction mixture was diluted with water (100 mL) and the aqueous phase was extracted with ethyl acetate (3 x 100 mL). The organic layers were combined, dried with anhydrous sodium sulfate, filtered and concentrated to give 4-cyano-2,6-difluorobenzoic acid (200 mg, 91.32% yield) as a white solid. 1H NMR (400 MHz, DMSO-d6): δ 7.95 (d, J = 7.53 Hz, 2H).

References

[1] Patent: WO2012/160464, 2012, A1. Location in patent: Page/Page column 69
[2] Patent: US2014/155398, 2014, A1. Location in patent: Paragraph 0415
[3] Patent: WO2011/28685, 2011, A1. Location in patent: Page/Page column 77; 78

4-CYANO-2,6-DIFLUOROBENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

4-CYANO-2,6-DIFLUOROBENZOIC ACID Suppliers

China 61 India 2 United Kingdom 3 United States 5 Global 71

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Ennopharm Co., Ltd.

Tel: +86 (21) 6435-5022
Country: China
ProdList: 4267
Advantage: 65

Wuhan Arike Technology Co., Ltd.

Tel: 027- 51832457 94518350
Fax: E-Mail Inquiry
Country: China
ProdList: 746
Advantage: 62

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

SynAsst Chemical.

Tel: 021-60343070
Fax: 021-35122006
Country: China
ProdList: 12740
Advantage: 55

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Xinyanhe Pharmatech Co.,Ltd

Tel: 0519-85252752 15366845260
Fax: 86-0519-85683352
Email: taihuaren@vip.163.com
Country: China
ProdList: 1124
Advantage: 58

ShangHai AmK Pharmaceutical Technology Co., Ltd.

Tel: 微信 17321281695 18019252918
Fax: 17321281695
Email: sale@amkchem.com
Country: China
ProdList: 15136
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5674
Advantage: 50

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Beijing Hechemist Technology CO.,LTD

Tel: 18511709189
Fax: 010-58043593
Email: sales@hechemist.com
Country: China
ProdList: 2835
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shijiazhuang Yesheng Chemical Technology Co., Ltd

Tel: 18031147013 18031147013;
Fax: 0311-68030586
Email: yeshengchemical@163.com
Country: China
ProdList: 2607
Advantage: 58

Shanghai Pingguo Pharmaceutical Co., Ltd.

Tel: 021-20432229
Fax: QQ2412110556
Email: 2412110556@qq.com
Country: China
ProdList: 6017
Advantage: 55

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Win-Win Chemical CO., Limited

Tel: 0577-64498589 15325081899
Fax: 0577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 1083
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-63315541 13323832564
Fax: QQ:3001332135
Email: 3001332135@qq.com
Country: China
ProdList: 9972
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

Allfluoro pharmaceutical co. ltd.

Tel: +86-400-0216110 +86-15958047586
Fax: 0086-21-33275002
Email: sales@allfluoro.com
Country: China
ProdList: 11385
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Wuxi Donghe Pharmaceutical Technology Co., Ltd.

Tel: 63313187 15358055255
Fax: QQ：63313187
Email: 63313187@qq.com
Country: China
ProdList: 1984
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-87569262 +86-15003564040
Fax: 029-88380327
Email: 1087@dideu.com
Country: China
ProdList: 3979
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Changzhou Kechem Bio-Scientific Co., LTD.

Tel: 0519-68985668 13685222090
Fax: qq735434464
Email: sales@kechem.cn
Country: China
ProdList: 26028
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9948
Advantage: 58

Shanghai Hongju Pharmaceutical Technology Co., LTD

Tel: 18001895509
Fax: QQ2934193566;
Email: 986383309@qq.com
Country: China
ProdList: 2680
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7985
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Shanghai Jinyin Biological Technology Co., Ltd

Tel: 021-20986266 18019349802
Email: 814527417@qq.com
Country: China
ProdList: 461
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9958
Advantage: 58

Anhui Henuo Biotechnology Co., Ltd

Tel: 18455579438
Country: China
ProdList: 16684
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697565236;
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 50000
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: syeu@accelachem.com
Country: China
ProdList: 11015
Advantage: 58

Huzhou Chengbo Biotechnology Co., Ltd

Tel: 13626726938
Country: China
ProdList: 3879
Advantage: 58

Olix (Shanghai) Pharmaceutical Technology Co., Ltd

Tel: 17316404525 17316404525
Email: 209533805@qq.com
Country: China
ProdList: 9765
Advantage: 58

Huzhou Qingliu Silicate Biotechnology Co., Ltd

Tel: 13626726938
Email: 15952452933@163.cn
Country: China
ProdList: 4109
Advantage: 58

Less

View Lastest Price from 4-CYANO-2,6-DIFLUOROBENZOIC ACID manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Cyano-2,6-difluorobenzoic acid 181073-82-5
Price: US $0.00-0.00/KG
Min. Order: 5mg
Purity: 99%HPLC
Supply Ability: 2000tons
Release date: 2020-01-07

181073-82-5, 4-CYANO-2,6-DIFLUOROBENZOIC ACIDRelated Search:

4-CYANO-2-FLUOROBENZOIC ACID 4-cyano-2,3,5,6-tetrafluorobenzoic acid 4-Cyanobenzoic acid 4-CYANO-2,6-DIFLUOROBENZOIC ACID 4-CYANO-2-FLUOROBENZALDEHYDE 3,5-DIFLUORO-4-FORMYLBENZONITRILE, 97% 4-Cyano-2-fluorobenzyl alcohol

4-Cyano-2,6-difluorobenzoic acid 95%

Benzoic acid, 4-cyano-2,6-difluoro-

181073-82-5