ChemicalBook > CAS DataBase List > 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Product Name: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID
CAS No.: 40155-43-9
Chemical Name: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID
Synonyms: 5-aminopyrazine-2-carboxylic;5-Aminopyrazine-2-carboxylicaci;2-amino-5-pirazinecarboxylic acid;2-Amino-5-pyrazinecarboxylic acid;5-AMINO-2-PYRAZINECARBOXYLIC ACID;5-AMINO-PYRAZINE-2-CARBOXYLIC ACID;2-Pyrazinecarboxylic acid, 5-amino-;Pyrazinecarboxylic acid, 5-amino- (7CI,9CI);5-AMINO-PYRAZINE-2-CARBOXYLIC ACID USP/EP/BP
CBNumber: CB2127255
Molecular Formula: C5H5N3O2
Formula Weight: 139.11
MOL File: 40155-43-9.mol

Less

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Property

Melting point:: 283 °C (decomp)
Boiling point:: 431.8±45.0 °C(Predicted)
Density: 1.533±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
form: Solid
pka: 4.41±0.10(Predicted)
Appearance: Light brown to off-white Solid
InChI: InChI=1S/C5H5N3O2/c6-4-2-7-3(1-8-4)5(9)10/h1-2H,(H2,6,8)(H,9,10)
InChIKey: FMEFOOOBIHQRMK-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=NC=C(N)N=C1
CAS DataBase Reference: 40155-43-9(CAS DataBase Reference)

Less

Safety

HazardClass: IRRITANT

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

TRC

Product number: A616530
Product name: 5-Aminopyrazine-2-carboxylicAcid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 057894
Product name: 5-Amino-pyrazine-2-carboxylic acid
Purity: 95%
Packaging: 500mg
Price: $55
Updated: 2021/12/16

Oakwood

Product number: 076096
Product name: 2-Amino-5-pyrazinecarboxylicacid
Purity: 95+%
Packaging: 1g
Price: $62
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA09828
Product name: 5-Amino-2-pyrazinecarboxylic acid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA09828
Product name: 5-Amino-2-pyrazinecarboxylic acid
Packaging: 2g
Price: $340
Updated: 2021/12/16

Less

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

36070-80-1

40155-43-9

The general procedure for the synthesis of 5-aminopyrazine-2-carboxylic acid from 5-chloropyrazine-2-carboxylic acid was as follows: first, the substitution reaction was carried out by substituting 5-chloropyrazine-2-carboxylic acid (317 mg, 2 mmol) with 25% (m/m) aqueous ammonia solution (3 mL) in a 10 mL microwave pressurized vial. The reaction conditions were set to 100 °C, 30 min, 80 W power output, and under stirring. This reaction was repeated 20 times to obtain sufficient amount of starting acid. Upon completion of the reaction, the vial contents were transferred to a petri dish, heated on a water bath with intermittent stirring until a dry solid (i.e., the ammonium salt form of the product) was obtained. To obtain the free acid form, the ammonium salt was dissolved in water and adjusted dropwise to pH 4 by addition of 10% hydrochloric acid.Subsequently, the mixture was cooled at room temperature for 5 min and then placed in a refrigerator for 15 min. The free acid crystals formed were collected by diafiltration and dried overnight. Next, the dried 5-aminopyrazine-2-carboxylic acid (278 mg, 2 mmol) was mixed with 3 mL of anhydrous propanol and 2 drops of concentrated sulfuric acid and placed in a microwave pressurized vial for esterification. The esterification conditions were 100 °C, 1 h and 80 W power output. The reaction process was monitored by TLC (unfolding agent: hexane/ethyl acetate, 1:3). Finally, the ester product was purified by fast chromatography with an elution gradient of 40% to 100% ethyl acetate in hexane solution.

References

[1] Molecules, 2017, vol. 22, # 10,

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

Less

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Suppliers

China 125 Czech Republic 1 Europe 1 Germany 1 India 2 United Kingdom 3 United States 15 Global 148

Suzhou Xinrui Biotechnology Co., Ltd.

Tel: 13401437572
Email: xinruibiotech01@163.com
Country: China
ProdList: 2741
Advantage: 58

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Shanghai Chemical Pharm-Intermediate Tech.Co., Ltd.

Tel: 21-54820552 18964669552
Fax: 086-21-64964478
Email: 188738128@qq.com
Country: China
ProdList: 310
Advantage: 66

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

shanghai Rainbow MediTech.Co.Ltd.

Tel: 021-64968085,64968086-5815,5812; 13472757003
Fax: +86 21 64968087
Email: xiaoxia.zeng@rainbowpharma.cn
Country: China
ProdList: 961
Advantage: 65

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Kohn & Shawn Pharmatech Co.,Ltd

Tel: 0931-4190454 13893344397
Fax: +86-931-8506154
Email: sales@kyxpharma.com
Country: China
ProdList: 310
Advantage: 55

Wuhan Taiyicheng Biopharmaceutical Co., Ltd.

Tel: 027-88320699
Fax: 027-88320962
Email: tycshyy@126.com
Country: China
ProdList: 297
Advantage: 66

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9510
Advantage: 58

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

EnliPharma Technology Co., Ltd

Tel: 0551-66399836 18955197623
Email: sales@enlipharma.com
Country: China
ProdList: 1876
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

CEG Chemical Science&Technology Co., Ltd.

Tel: Mobile:13665161512
Fax: +86-510-68873513
Country: China
ProdList: 1785
Advantage: 58

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Nanjing Fast Bio-Pharmaceutical Co.,Ltd.

Tel: 025-58390181 58390186 18912901218
Fax: 025-58390182
Email: sales@fastchem.cn
Country: China
ProdList: 162
Advantage: 60

Nanjing YiFan Biological Technology Co., Ltd.

Tel: 025-025-52700520 18914499889
Fax: 025-52700520
Email: sales@yfbiotech.com
Country: China
ProdList: 495
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66028182 18626450290
Email: yftan@aikonchem.com
Country: China
ProdList: 16679
Advantage: 50

AN PharmaTech Co Ltd

Tel: 86(21)68097365
Fax: 86(21)33321566
Email: sales@anpharma.net
Country: China
ProdList: 4891
Advantage: 55

Nanjing Chempioneer Pharmaceutical Co., Ltd.

Tel: 18068075658
Fax: -
Email: sales@chempioneer.com
Country: China
ProdList: 1811
Advantage: 58

NovoChemy Ltd.

Tel: 86-(0)21-31261262 373522135
Fax: 86-(0)21-33250524
Email: sales@novochemy.com
Country: China
ProdList: 6498
Advantage: 58

JW & Y Pharmlab Co., Ltd.

Tel: 021-64340559 13651849907;
Fax: 021- 64345308
Email: xinyu_shi@jwypharmlab.com.cn
Country: China
ProdList: 12000
Advantage: 58

Shanghai Kahn Pharmaceutical Co., Ltd.

Tel: 021-34979681; 17701870669
Fax: 021-34979681
Email: 41513101@qq.com
Country: China
ProdList: 1785
Advantage: 55

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7991
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Shijiazhuang Sdyano Fine Chemical Co., Ltd.

Tel: 0311-89250318 031166536426
Fax: 4000311741
Email: master@sjzsdyn.com
Country: China
ProdList: 3495
Advantage: 58

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

Hangzhou Molcore Biopharmatech Co.,Ltd

Tel: 400-711-5280 86-571-81025280
Fax: 86-571-85806285
Email: sales@molcore.com
Country: China
ProdList: 9967
Advantage: 58

Sichuan BaiPeng Biotechnology Co., Ltd.

Tel: 028-65791793 18140026355
Fax: QQ568470422
Email: 568470422@qq.com
Country: China
ProdList: 9997
Advantage: 58

Wuxi AppTec

Tel: 022-59987777 13552403979
Email: jia_guoqiang@wuxiapptec.com
Country: China
ProdList: 22345
Advantage: 58

Suzhou Nuoouman Biological Technology Co., Ltd.

Tel: 15026866316
Email: 180642609@qq.com
Country: China
ProdList: 4967
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Zhengzhou Ruke Biological Co., Ltd.

Tel: 15981811963
Fax: QQ：1410472904
Email: 1410472904@qq.com
Country: China
ProdList: 5825
Advantage: 58

Henan Aosman Biotechnology Co., LTD

Tel: 0371-0371-61318675 17719817155
Fax: 0371-61318675
Email: sales@xlinebio.com
Country: China
ProdList: 2857
Advantage: 58

3A Chemicals

Tel: 400-668-9898
Fax: 010-51582189
Email: service@3achem.com
Country: China
ProdList: 20557
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Cool Pharm, Ltd

Tel: 021-58581007 18019463053
Fax: 021-50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12878
Advantage: 58

wuhan Dekray Biomedical Technology Co.,Ltd

Tel: 027-69573188 18221423799
Email: 1503407886@qq.com
Country: China
ProdList: 1439
Advantage: 58

Lanzhou Kangyuxin Biotechnology Co., Ltd.

Tel: 0931-4190454 13893344397
Email: sales@kyxpharma.com
Country: China
ProdList: 3153
Advantage: 58

Suzhou Vosun Biotech Co.,Ltd

Tel: 18934576691
Fax: 0512-82177265
Email: yq@vosunbio.com
Country: China
ProdList: 735
Advantage: 58

Shanghai zhigan biotechnology co., LTD

Tel
Email: zhiqianbio@126.com
Country: China
ProdList: 19778
Advantage: 58

Finetech Industry Limited

Tel: +86-27-8746-5837 +8619945049750
Fax: 86 27 87772287
Email: info@finetechnology-ind.com
Country: China
ProdList: 9629
Advantage: 58

Less

View Lastest Price from 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID 40155-43-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Career Henan Chemical Co

Product: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID 40155-43-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

40155-43-9, 5-AMINO-PYRAZINE-2-CARBOXYLIC ACIDRelated Search:

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID ETHYL ESTER,5-AMINO-PYRAZINE-2-CARBOXYLIC ACID ETHYL ETHER 5-Aminopyrazine-2-carboxylic acid methyl ester 3-Pyrimidin-5-yl-benzoic acid methyl ester Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Aminopyrazine 2-Pyrazinecarboxylic acid 2-Amino-3-bromopyrazine-5-carboxylic Acid 2-AMINO-4-HYDROXYPTERIDINE-6-CARBOXYLIC ACID RARECHEM AL BO 1272 METHYL 3-AMINO-5-(BENZYLAMINO)-6-CHLOROPYRAZINE-2-CARBOXYLATE 5-BOC-AMINO-PYRAZINE-2-CARBOXYLIC ACID METHYL 3-AMINO-6-CHLORO-5-[(2-THIENYLMETHYL)AMINO]PYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-MORPHOLINOPYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-PIPERIDINOPYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-(ISOPROPYLAMINO)PYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-(1,4-THIAZINAN-4-YL)PYRAZINE-2-CARBOXYLATE RARECHEM AL BO 0788

5-AMINO-2-PYRAZINECARBOXYLIC ACID

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Pyrazinecarboxylic acid, 5-amino- (7CI,9CI)

5-aminopyrazine-2-carboxylic

2-Amino-5-pyrazinecarboxylic acid

2-amino-5-pirazinecarboxylic acid

2-Pyrazinecarboxylic acid, 5-amino-

5-Aminopyrazine-2-carboxylicaci

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID USP/EP/BP

40155-43-9

pharmacetical

Alcohols and Derivatives

Heterocycles

AMINOACID