ChemicalBook > CAS DataBase List > 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Product Name: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID
CAS No.: 40155-43-9
Chemical Name: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID
Synonyms: 5-aminopyrazine-2-carboxylic;5-Aminopyrazine-2-carboxylicaci;2-amino-5-pirazinecarboxylic acid;2-Amino-5-pyrazinecarboxylic acid;5-AMINO-2-PYRAZINECARBOXYLIC ACID;5-AMINO-PYRAZINE-2-CARBOXYLIC ACID;2-Pyrazinecarboxylic acid, 5-amino-;Pyrazinecarboxylic acid, 5-amino- (7CI,9CI);5-AMINO-PYRAZINE-2-CARBOXYLIC ACID USP/EP/BP
CBNumber: CB2127255
Molecular Formula: C5H5N3O2
Formula Weight: 139.11
MOL File: 40155-43-9.mol

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5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Property

Melting point:: 283 °C (decomp)
Boiling point:: 431.8±45.0 °C(Predicted)
Density: 1.533±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
form: Solid
pka: 4.41±0.10(Predicted)
Appearance: Light brown to off-white Solid
InChI: InChI=1S/C5H5N3O2/c6-4-2-7-3(1-8-4)5(9)10/h1-2H,(H2,6,8)(H,9,10)
InChIKey: FMEFOOOBIHQRMK-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=NC=C(N)N=C1
CAS DataBase Reference: 40155-43-9(CAS DataBase Reference)

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Safety

HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC

Product number: A616530
Product name: 5-Aminopyrazine-2-carboxylicAcid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Matrix Scientific

Product number: 057894
Product name: 5-Amino-pyrazine-2-carboxylic acid
Purity: 95%
Packaging: 500mg
Price: $55
Updated: 2021/12/16

Oakwood

Product number: 076096
Product name: 2-Amino-5-pyrazinecarboxylicacid
Purity: 95+%
Packaging: 1g
Price: $62
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA09828
Product name: 5-Amino-2-pyrazinecarboxylic acid
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA09828
Product name: 5-Amino-2-pyrazinecarboxylic acid
Packaging: 250mg
Price: $100
Updated: 2021/12/16

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5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

36070-80-1

40155-43-9

The general procedure for the synthesis of 5-aminopyrazine-2-carboxylic acid from 5-chloropyrazine-2-carboxylic acid was as follows: first, the substitution reaction was carried out by substituting 5-chloropyrazine-2-carboxylic acid (317 mg, 2 mmol) with 25% (m/m) aqueous ammonia solution (3 mL) in a 10 mL microwave pressurized vial. The reaction conditions were set to 100 °C, 30 min, 80 W power output, and under stirring. This reaction was repeated 20 times to obtain sufficient amount of starting acid. Upon completion of the reaction, the vial contents were transferred to a petri dish, heated on a water bath with intermittent stirring until a dry solid (i.e., the ammonium salt form of the product) was obtained. To obtain the free acid form, the ammonium salt was dissolved in water and adjusted dropwise to pH 4 by addition of 10% hydrochloric acid.Subsequently, the mixture was cooled at room temperature for 5 min and then placed in a refrigerator for 15 min. The free acid crystals formed were collected by diafiltration and dried overnight. Next, the dried 5-aminopyrazine-2-carboxylic acid (278 mg, 2 mmol) was mixed with 3 mL of anhydrous propanol and 2 drops of concentrated sulfuric acid and placed in a microwave pressurized vial for esterification. The esterification conditions were 100 °C, 1 h and 80 W power output. The reaction process was monitored by TLC (unfolding agent: hexane/ethyl acetate, 1:3). Finally, the ester product was purified by fast chromatography with an elution gradient of 40% to 100% ethyl acetate in hexane solution.

References

[1] Molecules, 2017, vol. 22, # 10,

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Suppliers

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View Lastest Price from 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID 40155-43-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-11

Career Henan Chemical Co

Product: 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID 40155-43-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-01

40155-43-9, 5-AMINO-PYRAZINE-2-CARBOXYLIC ACIDRelated Search:

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID ETHYL ESTER,5-AMINO-PYRAZINE-2-CARBOXYLIC ACID ETHYL ETHER 5-Aminopyrazine-2-carboxylic acid methyl ester 3-Pyrimidin-5-yl-benzoic acid methyl ester Methyl 3,5-diamino-6-chloropyrazine-2-carboxylate 5-AMINO-PYRAZINE-2-CARBOXYLIC ACID Aminopyrazine 2-Pyrazinecarboxylic acid 2-Amino-3-bromopyrazine-5-carboxylic Acid 2-AMINO-4-HYDROXYPTERIDINE-6-CARBOXYLIC ACID RARECHEM AL BO 1272 METHYL 3-AMINO-5-(BENZYLAMINO)-6-CHLOROPYRAZINE-2-CARBOXYLATE 5-BOC-AMINO-PYRAZINE-2-CARBOXYLIC ACID METHYL 3-AMINO-6-CHLORO-5-[(2-THIENYLMETHYL)AMINO]PYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-MORPHOLINOPYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-PIPERIDINOPYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-(ISOPROPYLAMINO)PYRAZINE-2-CARBOXYLATE METHYL 3-AMINO-6-CHLORO-5-(1,4-THIAZINAN-4-YL)PYRAZINE-2-CARBOXYLATE RARECHEM AL BO 0788

5-AMINO-2-PYRAZINECARBOXYLIC ACID

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID

Pyrazinecarboxylic acid, 5-amino- (7CI,9CI)

5-aminopyrazine-2-carboxylic

2-Amino-5-pyrazinecarboxylic acid

2-amino-5-pirazinecarboxylic acid

2-Pyrazinecarboxylic acid, 5-amino-

5-Aminopyrazine-2-carboxylicaci

5-AMINO-PYRAZINE-2-CARBOXYLIC ACID USP/EP/BP

40155-43-9

pharmacetical

Alcohols and Derivatives

Heterocycles

AMINOACID