1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
- Product Name
- 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
- CAS No.
- 6001-64-5
- Chemical Name
- 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE
- Synonyms
- MET;CHLOROBUTANOL HEMIHYDRATE;CHLORETONE;CHLOROBUTANOL HYDROUS;CHLORBUTE;CHLORBUTOL;MET HEMIHYDRATE;ACETONE CHLOROFORM;Chlorobutanol Base;ACETONE CHLOROFORME
- CBNumber
- CB2134363
- Molecular Formula
- C8H16Cl6O3
- Formula Weight
- 372.93
- MOL File
- 6001-64-5.mol
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Property
- Melting point:
- 77-79 °C(lit.)
- Boiling point:
- 173-175 °C
- Flash point:
- 100 °C
- storage temp.
- 2-8°C
- solubility
- Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent).
- form
- Crystalline Powder, Crystals and/or Chunks
- color
- White to almost white
- Water Solubility
- Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.
- Merck
- 14,2129
- BRN
- 878167
- Stability:
- Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
- LogP
- 2.074 (est)
- CAS DataBase Reference
- 6001-64-5
Safety
- Hazard Codes
- Xn
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- RTECS
- UC0175000
- TSCA
- Yes
- HS Code
- 29055900
N-Bromosuccinimide Price
- Product number
- SAB1305534
- Product name
- MONOCLONAL ANTI-BI-PHOSPHO-MET/HGFR(Y1234/Y1235) antibody produced in mouse
- Purity
- clone 6AT1877, IgG fraction of antiserum, buffered aqueous solution
- Packaging
- 400μl
- Price
- $481
- Updated
- 2024/03/01
- Product number
- 112054
- Product name
- 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
- Purity
- 98%
- Packaging
- 50g
- Price
- $57
- Updated
- 2024/03/01
- Product number
- 1112503
- Product name
- Chlorobutanol
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $491
- Updated
- 2024/03/01
- Product number
- Y0002029
- Product name
- Chlorobutanol hemihydrate
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- Y0002029
- Price
- $150
- Updated
- 2023/01/07
- Product number
- 1.01005
- Product name
- 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
- Purity
- EMPROVE? ESSENTIAL, Ph. Eur., BP, JP, NF
- Packaging
- 1KG
- Price
- $221
- Updated
- 2022/05/15
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Chemical Properties,Usage,Production
Chemical Properties
white crystalline solid
Uses
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate in combination with dimethyl sulfone, can serve as an appropriate solvent for the freeze drying of certain parenteral organic drugs, which have an increase in many factors such as stability, dissolution rate, dosing accuracy and sterility.
Uses
Pharmaceutic aid (antimicrobial agent).
Uses
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate converts benzisoxazole to α-aryloxyisobutyric acid. It forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.
brand name
Chloretone (Parke-Davis).
General Description
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) converts benzisoxazole to α-aryloxyisobutyric acid. 1,1,1-Trichloro-2-methyl-2-propanol hemihydrate (chlorobutanol) forms eutectic with dimethyl sulfone, which is the most suitable media for freeze-drying due to its high solubilizing ability and a good rate of solvent removal.
Biochem/physiol Actions
Chlorobutanol or 1,1,1-Trichloro-2-methyl-2-propanol is a opthalmic preservative and sedative hypnotic that possess antibacterial and antifungal properties. It also decreases the conduction velocity and induces conduction failure and automaticity within isolated ventricular muscle strips as well as impacts myocardial cells by acting on cell membrane and reduces isometric tension produced by heart.
1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE manufacturers
- Product
- Chlorobutanol 6001-64-5
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%~101.0%
- Supply Ability
- 5000kg/month
- Release date
- 2021-06-18
- Product
- 1,1,1-TRICHLORO-2-METHYL-2-PROPANOL HEMIHYDRATE 6001-64-5
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-12-11
- Product
- 1,1,1-Trichloro-2-Methyl-2-Propanol Hemihydrate 6001-64-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-29