Asymmetric dimethylarginine
- Product Name
- Asymmetric dimethylarginine
- CAS No.
- 30315-93-6
- Chemical Name
- Asymmetric dimethylarginine
- Synonyms
- ArginineImpurity12;H-Arg(NMe2)-OH(asym);N,N-dimethylarginine;Asymmetric dimethylarginine;Asymmetric dimethylarginine(ADMA);L-Arg(Me,Me)-OH(asymmetrical), >97%;N(omega),N(omega)-dimethyl-L-arginine;L-Ornithine, N5-[(dimethylamino)iminomethyl]-;Arginine Impurity 12(N, N-Dimethyl-L-Arginine);N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%
- CBNumber
- CB21351907
- Molecular Formula
- C8H18N4O2
- Formula Weight
- 202.25
- MOL File
- 30315-93-6.mol
Asymmetric dimethylarginine Property
- Boiling point:
- 340.8±52.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble
- form
- A crystalline solid
- pka
- 2.50±0.24(Predicted)
- color
- White to off-white
- InChI
- 1S/C8H18N4O2/c1-12(2)8(10)11-5-3-4-6(9)7(13)14/h6H,3-5,9H2,1-2H3,(H2,10,11)(H,13,14)/t6-/m0/s1
- InChIKey
- YDGMGEXADBMOMJ-LURJTMIESA-N
- SMILES
- N[C@@H](CCC\N=C(\N(C)C)/N)C(=O)O
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SMB00938
- Product name
- Dimethyl-L-arginine
- Purity
- ≥95% (HPLC)
- Packaging
- 100MG
- Price
- $237
- Updated
- 2026/04/30
- Product number
- SMB00938
- Product name
- Dimethyl-L-arginine
- Purity
- ≥95%(HPLC)
- Packaging
- 500MG
- Price
- $570
- Updated
- 2026/04/30
- Product number
- 33576
- Product name
- NG,NG-dimethyl-L-Arginine
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $36
- Updated
- 2026/04/30
- Product number
- 33576
- Product name
- NG,NG-dimethyl-L-Arginine
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $63
- Updated
- 2026/04/30
- Product number
- 33576
- Product name
- NG,NG-dimethyl-L-Arginine
- Purity
- ≥95%
- Packaging
- 25mg
- Price
- $128
- Updated
- 2026/04/30
Asymmetric dimethylarginine Chemical Properties,Usage,Production
Uses
Metabolomics
Definition
ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.
General Description
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.
IC 50
Human Endogenous Metabolite
Asymmetric dimethylarginine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Asymmetric dimethylarginine manufacturers
- Product
- N,N-dimethylarginine 30315-93-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-25