N,N-dimethylarginine
- Product Name
- N,N-dimethylarginine
- CAS No.
- 30315-93-6
- Chemical Name
- N,N-dimethylarginine
- Synonyms
- ArginineImpurity12;H-Arg(NMe2)-OH(asym);N,N-dimethylarginine;Asymmetric dimethylarginine;L-Arg(Me,Me)-OH(asymmetrical), >97%;N(omega),N(omega)-dimethyl-L-arginine;L-Ornithine, N5-[(dimethylamino)iminomethyl]-;Arginine Impurity 12（N, N-Dimethyl-L-Arginine）;N5-[(Dimethylamino)iminomethyl]-L-ornithine, 97%;(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid
- CBNumber
- CB21351907
- Molecular Formula
- C8H18N4O2
- Formula Weight
- 202.25
- MOL File
- 30315-93-6.mol
N,N-dimethylarginine Property
- Boiling point:
- 340.8±52.0 °C(Predicted)
- Density
- 1.23±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- solubility
- DMF: 5 mg/ml; DMSO: 3 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): freely soluble
- form
- A crystalline solid
- pka
- 2.50±0.24(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SMB00938
- Product name
- Dimethyl-L-arginine
- Purity
- ≥95% (HPLC)
- Packaging
- 100MG
- Price
- $210
- Updated
- 2024/03/01
- Product number
- SMB00938
- Product name
- Dimethyl-L-arginine
- Purity
- ≥95%(HPLC)
- Packaging
- 500MG
- Price
- $524
- Updated
- 2024/03/01
- Product number
- CS-0059330
- Product name
- Asymmetricdimethylarginine
- Purity
- >98.0%
- Packaging
- 250mg
- Price
- $195
- Updated
- 2021/12/16
- Product number
- CS-0059330
- Product name
- Asymmetricdimethylarginine
- Purity
- >98.0%
- Packaging
- 1g
- Price
- $495
- Updated
- 2021/12/16
- Product number
- CS-0059330
- Product name
- Asymmetricdimethylarginine
- Purity
- >98.0%
- Packaging
- 5g
- Price
- $1485
- Updated
- 2021/12/16
N,N-dimethylarginine Chemical Properties,Usage,Production
Uses
Metabolomics
Definition
ChEBI: A L-arginine derivative having two methyl groups both attached to the primary amino moiety of the guanidino group.
General Description
Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.
N,N-dimethylarginine Preparation Products And Raw materials
Raw materials
Preparation Products
N,N-dimethylarginine Suppliers
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