3-Fluoropyridine-2-carboxylic acid
- Product Name
- 3-Fluoropyridine-2-carboxylic acid
- CAS No.
- 152126-31-3
- Chemical Name
- 3-Fluoropyridine-2-carboxylic acid
- Synonyms
- 3-Fluoropicolinicaci;3-FLUOROPICOLINIC ACID;REF DUPL: 3-fluoropicolinic acid;3-Fluoropyridin-2-carboxylic acid;3-fluropyridine-2-carboxylic acid;3-Fluoro-2-pyridinecarboxylic acid;3-FLUOROPYRIDINE-2-CARBOXYLIC ACID;3-Fluoropyridine-3-Carboxylic Acid;2-Pyridinecarboxylicacid, 3-fluoro-;3-Fluoropyridine-2-carboxylicacid98%
- CBNumber
- CB2140247
- Molecular Formula
- C6H4FNO2
- Formula Weight
- 141.1
- MOL File
- 152126-31-3.mol
3-Fluoropyridine-2-carboxylic acid Property
- Melting point:
- 154°C
- Boiling point:
- 265.2±20.0 °C(Predicted)
- Density
- 1.419±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- pka
- 2.71±0.10(Predicted)
- form
- powder
- color
- White
- InChI
- InChI=1S/C6H4FNO2/c7-4-2-1-3-8-5(4)6(9)10/h1-3H,(H,9,10)
- InChIKey
- IRERRSXDWUCFIY-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=NC=CC=C1F
- CAS DataBase Reference
- 152126-31-3(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- HazardClass
- IRRITANT
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F621400
- Product name
- 3-Fluoropicolinicacid
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- F1709
- Product name
- 3-Fluoropyridine-2-carboxylicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $8
- Updated
- 2021/12/16
- Product number
- 032594
- Product name
- 3-Fluoro-2-pyridinecarboxylic acid
- Purity
- 98%
- Packaging
- 1g
- Price
- $14
- Updated
- 2021/12/16
- Product number
- PC7057
- Product name
- 3-Fluoropyridine-2-carboxylicacid
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
- Product number
- 4H21-3-Y7
- Product name
- 3-Fluoropyridine-2-carboxylic acid
- Packaging
- 1g
- Price
- $16
- Updated
- 2021/12/16
3-Fluoropyridine-2-carboxylic acid Chemical Properties,Usage,Production
Uses
3-Fluoropyridine-2-carboxylic acid is mainly used as an intermediate in organic synthesis and medicinal chemistry. It is a synthetic intermediate of tridentate nitrogen ligands in pesticide molecules and transition metal catalytic reactions.
Synthesis
372-47-4
124-38-9
152126-31-3
To a diethyl ether (50 ml) solution of 1,4-diazabicyclo[2.2.2]octane (1.15 g, 10.3 mmol) was slowly added n-butyllithium (2.6 M hexane solution, 3.95 ml, 10.3 mmol) dropwise at -78 °C. The reaction mixture was stirred at -20°C for 1 hr, then a diethyl ether (30 ml) solution of 3-fluoropyridine (1.00 g, 10.29 mmol) was added dropwise at -78°C. The resulting yellow suspension was stirred at -60°C for 1 hr and subsequently cooled to -78°C and an excess of dry ice was added. The reaction solution was slowly warmed to -10°C over a period of 20 min. The precipitate was collected by filtration and the residue was washed with ether to give pure 3-fluoropyridine-2-carboxylic acid (1.20 g, 8.51 mmol, 83% yield).
References
[1] Tetrahedron, 1998, vol. 54, # 42, p. 12859 - 12886
[2] Patent: WO2014/82737, 2014, A1. Location in patent: Page/Page column 38
3-Fluoropyridine-2-carboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
3-Fluoropyridine-2-carboxylic acid Suppliers
- Tel
- 0418-2868000 13464847801
- Fax
- +86-418-3810066
- jingxuan.lu@fcmeditech.com
- Country
- China
- ProdList
- 342
- Advantage
- 55
- Tel
- 86-0531-68658065 15726150375
- Fax
- 0531-68658065
- 1071018499@qq.com
- Country
- China
- ProdList
- 526
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- +49 3493/605464
- Fax
- +49 3493/605470
- sales@intatrade.de
- Country
- Germany
- ProdList
- 3572
- Advantage
- 66
- Tel
- 021-20221225 13917446399
- Fax
- QQ:115820162
- zwchem@163.com
- Country
- China
- ProdList
- 617
- Advantage
- 61
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2809
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
View Lastest Price from 3-Fluoropyridine-2-carboxylic acid manufacturers
- Product
- 3-FLUOROPYRIDINE-2-CARBOXYLIC ACID 152126-31-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-26
- Product
- 3-Fluoropyridine-2-carboxylicacid 152126-31-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-14
- Product
- 3-Fluoropyridine-2-carboxylic acid 152126-31-3
- Price
- US $0.00/kg
- Min. Order
- 25kg
- Purity
- 98%
- Supply Ability
- Inquiry
- Release date
- 2023-07-12