6-Fluoronicotinic acid

Product Name: 6-Fluoronicotinic acid
CAS No.: 403-45-2
Chemical Name: 6-Fluoronicotinic acid
Synonyms: uoronicotinic acid;6-Fluoronicotinicaci;6-Fluoronicotinc Acid;6-Floronicotinic acid;6-FLUORONICOTINIC ACID;6-Fluoronicotinicacid98%;6-FluoronicotinicAcid>6-Fluoronicotinic acid 98%;6-FLUOROPYRIDINE-3-FORMIC ACID;6-Fluoropyridin-3-carboxylic acid
CBNumber: CB2316945
Molecular Formula: C6H4FNO2
Formula Weight: 141.1
MOL File: 403-45-2.mol

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6-Fluoronicotinic acid Property

Melting point:: 144-148 °C(lit.)
Boiling point:: 309.4±22.0 °C(Predicted)
Density: 1.419±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 3.41±0.10(Predicted)
color: White to Orange to Green
InChI: InChI=1S/C6H4FNO2/c7-5-2-1-4(3-8-5)6(9)10/h1-3H,(H,9,10)
InChIKey: UJDLCTNVHJEBDG-UHFFFAOYSA-N
SMILES: C1=NC(F)=CC=C1C(O)=O
CAS DataBase Reference: 403-45-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 593761
Product name: 6-Fluoropyridine-3-carboxylic acid
Purity: 97%
Packaging: 250mg
Price: $94.05
Updated: 2025/07/31

TCI Chemical

Product number: F0695
Product name: 6-Fluoronicotinic Acid
Purity: >98.0%(GC)
Packaging: 1g
Price: $115
Updated: 2025/07/31

TCI Chemical

Product number: F0695
Product name: 6-Fluoronicotinic Acid
Purity: >98.0%(GC)
Packaging: 5g
Price: $286
Updated: 2025/07/31

TCI Chemical

Product number: F0695
Product name: 6-Fluoronicotinic Acid
Purity: >98.0%(GC)
Packaging: 200mg
Price: $30
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: HCH0019994
Product name: 6-FLUORONICOTINIC ACID
Purity: 95.00%
Packaging: 5G
Price: $848.93
Updated: 2021/12/16

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6-Fluoronicotinic acid Chemical Properties,Usage,Production

Chemical Properties

White to Orange to Green powder to crystal.

Uses

6-Fluoronicotinic acid is a fluorinated nicotinic acid that is a derivative of pyridine, with a carboxylic acid at 3-position and a fluorine at 6-position. It is used as a pharmaceutical intermediate and a molecular scaffold to synthesize tracers for positron emission tomography, for visualizing and measuring changes in metabolic processes.

References

[1] LATIFA RBAH-VIDAL. Early detection and longitudinal monitoring of experimental primary and disseminated melanoma using [¹⁰F]ICF01006, a highly promising melanoma PET tracer.[J]. European Journal of Nuclear Medicine and Molecular Imaging, 2012, 39 9: 1449-1461. DOI:10.1007/s00259-012-2168-y.
[2] FALGUNI BASULI. Fast indirect fluorine-18 labeling of protein/peptide using the useful 6-fluoronicotinic acid-2,3,5,6-tetrafluorophenyl prosthetic group: A method comparable to direct fluorination.[J]. Journal of labelled compounds & radiopharmaceuticals, 2017, 60 3 1: 168-175. DOI:10.1002/jlcr.3487.
[3] G. F. HAWKINS ARTHUR R. THE PREPARATION OF 5-FLUORONICOTINIC ACID AND 5-FLUORONICOTINAMIDE1[J]. The Journal of Organic Chemistry, 1949, 14 2: 328-332. DOI:10.1021/jo01154a021.
[4] Lal, Achchhe, and Devendra Kumar Singh. "Theoretical and Experimental Studies of Vibrational Spectra of 6-fluoronicotinc Acid."

6-Fluoronicotinic acid Preparation Products And Raw materials

Raw materials

2-Amino-5-methylpyridine Sodium nitrite Fluoroboric acid Potassium permanganate

Preparation Products

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6-Fluoronicotinic acid Suppliers

Americas 1 Canada 1 China 258 Europe 3 France 1 Germany 9 India 19 Italy 1 Japan 1 Switzerland 3 United Kingdom 14 United States 41 Global 352

Fuxin Yuke Chemical Technology Co., Ltd.

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Shandong Zhishang Chemical Co. LTD

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J & K SCIENTIFIC LTD.

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Liaoning Tianhua Chemical Co., Ltd.

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3B Pharmachem (Wuhan) International Co.,Ltd.

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Alfa Aesar

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TCI (Shanghai) Development Co., Ltd.

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ShangHai DEMO Chemical Co.,Ltd

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Fax: 0086-21-50182339
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View Lastest Price from 6-Fluoronicotinic acid manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 6-Fluoronicotinic acid 403-45-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 10000KGS
Release date: 2025-05-30

Hebei Chuanghai Biotechnology Co., Ltd

Product: 6-Fluoronicotinic acid 403-45-2
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-25

Hebei Zhuanglai Chemical Trading Co Ltd

Product: 6-Fluoronicotinic acid 403-45-2
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 ton
Release date: 2024-12-23

403-45-2, 6-Fluoronicotinic acidRelated Search:

Isonicotinic acid EPA 2-Fluoropyridine QUINOLINE-3-CARBOXYLIC ACID Xanthinol nicotinate N,N-Dimethylpropionamide 2,2-Dimethylbutyryl chloride 2-Phenylbutyric acid 4,6-Difluoronicotinic acid 4-Chloro-5,6-difluoropyridine-3-carboxylic acid 2,6-Difluoropyridine-3-carboxylic acid 6-FLUORO-2-METHYLNICOTINIC ACID 6-FLUORONICOTINIC ACID METHYL ESTER 2-FLUORO-3-METHYL-PYRIDINE-5-CARBOXYLIC ACID 4-FLUORONICOTINIC ACID 2,6-Dichloro-5-fluoronicotinic acid 97%,2,6-DICHLORO-5-FLUORONICOTINIC ACID 3-FLUORONICOTINIC ACID 3-Bromo-2-fluoro--pyridine-5-carboxylic acid

2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine, 3-Carboxy-6-fluoropyridine

6-Floronicotinic acid

6-Fluoronicotinc Acid

2-Fluoropyridine-5-carboxylic acid, 6-Fluoropyridine-3-carboxylic acid, 5-Carboxy-2-fluoropyridine

2-FLUOROPYRIDINE-5-CARBOXYLIC ACID

2-FLUORO-5-PYRIDINE CARBOXYLIC ACID

2-Fluoro-5-pyridine carboxylic acid(6-Fluoronicotinic acid)

6-FLUORONICOTINIC ACID

6-FLUOROPYRIDINE-3-CARBOXYLIC ACID

6-FLUOROPYRIDINE-3-FORMIC ACID

6-FLUORO-3-PYRIDINECARBOXYLIC ACID

6-Fluoronicotinic acid 98%

6-Fluoronicotinicacid98%

3-Pyridinecarboxylic acid,6-fluoro-

6-FluoronicotinicAcid&gt

uoronicotinic acid

6-Fluoronicotinic acid ISO 9001：2015 REACH

6-Fluoropyridin-3-carboxylic acid

6-Fluoronicotinicaci

403-45-2

403-45-1

C6H4FNO2

Building Blocks

Pyridines

Heterocyclic Building Blocks

C6

Chemical Synthesis

Fluorinated Building Blocks

Heterocyclic Building Blocks

Heterocyclic Fluorinated Building Blocks

Other Fluorinated Heterocycles

Picolinic acid series

Pyridine

Pyridine series

Pyridines

Building Blocks

Carboxy

Boronic Acid

API

C6