3-Fluoropyridine-4-carboxylic acid

Product Name: 3-Fluoropyridine-4-carboxylic acid
CAS No.: 393-53-3
Chemical Name: 3-Fluoropyridine-4-carboxylic acid
Synonyms: 3-FLUOROISONICOTINIC ACID;3-FLUOROISON;3-fluoroisonic acid;3-Fluoroisonicotinic;3-FLUORONICOTINIC ACID;3- fluorineisonicotinic acid;3-Fluoro-4-pyridinecarboxylic;3-Fluoroisonicotinic Acid, 97+%;3-Fluoropyridine-4-carboxylicaci;3-Fluoropyridin-4-carboxylic acid
CBNumber: CB5433900
Molecular Formula: C6H4FNO2
Formula Weight: 141.1
MOL File: 393-53-3.mol

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3-Fluoropyridine-4-carboxylic acid Property

Melting point:: 251-254°C (dec.)
Boiling point:: 360.0±22.0 °C(Predicted)
Density: 1.419±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 2.85±0.10(Predicted)
form: solid
color: White to off-white
BRN: 383678
InChIKey: POLXLLIQWDBJMD-UHFFFAOYSA-N
CAS DataBase Reference: 393-53-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,F
Risk Statements: 36/37/38-10
Safety Statements: 26-36-16
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 638757
Product name: 3-Fluoro-4-pyridinecarboxylic acid
Purity: 97%
Packaging: 1g
Price: $30.2
Updated: 2023/06/20

Sigma-Aldrich

Product number: 638757
Product name: 3-Fluoro-4-pyridinecarboxylic acid
Purity: 97%
Packaging: 10g
Price: $278
Updated: 2023/06/20

TCI Chemical

Product number: F0477
Product name: 3-Fluoroisonicotinic Acid
Purity: min. 98.0 %
Packaging: 5G
Price: $47
Updated: 2025/07/31

TCI Chemical

Product number: F0477
Product name: 3-Fluoroisonicotinic Acid
Purity: min. 98.0 %
Packaging: 25G
Price: $140
Updated: 2025/07/31

TRC

Product number: F592118
Product name: 3-Fluoroisonicotinicacid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

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3-Fluoropyridine-4-carboxylic acid Chemical Properties,Usage,Production

Synthesis

124-38-9

393-53-3

3-Fluoropyridine (25 g, 257 mmol) was slowly added dropwise to a solution of tetrahydrofuran (600 mL) containing butyl lithium (270 mmol) and diisopropylamine (27.4 g, 271 mmol) at -78 °C. The reaction mixture was stirred continuously at this temperature for 1 hour. Subsequently, crushed dry ice was added to the reaction system and gradually warmed to room temperature over 1 hour. Upon completion of the reaction, the pH of the reaction solution was adjusted to 5 with an aqueous solution of hydrogen chloride and acidified. The resulting precipitate was collected by filtration and dried. The final 3-fluoroisonicotinic acid (25.2 g, 179 mmol, 70% yield) was obtained as colorless crystals.

References

[1] Patent: WO2006/36015, 2006, A2. Location in patent: Page/Page column 121-122

3-Fluoropyridine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Fluoropyridine-4-carboxylic acid Suppliers

China 192 Germany 4 India 7 Italy 1 Switzerland 1 United Kingdom 6 United States 31 Global 242

DKD Shijiazhuang Chemical Co., Ltd.

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View Lastest Price from 3-Fluoropyridine-4-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-Fluoropyridine-4-carboxylic acid 393-53-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

henan kanbei chemical co.,ltd

Product: 3-Fluoropyridine-4-carboxylic acid 393-53-3
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2022-09-26

Honest Joy Holdings Limited

Product: 3-Fluoroisonicotinic acid 393-53-3
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.2%
Supply Ability: 100 tons
Release date: 2022-02-21

393-53-3, 3-Fluoropyridine-4-carboxylic acidRelated Search:

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3-FLUOROPYRIDINE-4-CARBOXYLIC ACID

3-FLUOROISONICOTINIC ACID

3-FLUORO-4-PYRIDINECARBOXYLIC ACID

3-Fluoropyridine-4-carboxylic acid mono hydrate

3-Fluoroisonicotinic

3-FLUORONICOTINIC ACID

3-FLUOROISONICOTINIC ACID MONO HYDRATE

3-Fluoro-4-pyridinecarboxylic

3-fluoroisonic acid

3-Fluoropyridine-4-carboxylic acid, 4-Carboxy-3-fluoropyridine

3- fluorineisonicotinic acid

3-Fluoroisonicotinic Acid, 97+%

3-Fluoropyridine-4-carboxylicacid,97%

3-Fluoro-4-pyridinecarboxylic acid 97%

4-Pyridinecarboxylicacid, 3-fluoro-

3-Fluoroisonicotinic Acid(WX614062)

3-FLUOROISON

3-Fluoropyridine-4-carboxylicaci

3-Fluoropyridine-4-carboxylic acid ISO 9001：2015 REACH

3-Fluoropyridin-4-carboxylic acid

393-53-3

C6H4FNO2H2O

Building Blocks

Heterocyclic Building Blocks

Pyridines

C6

Fluorine series

Morpholines/Thiomorpholines

Building Blocks

Fluorinated

blocks

Carboxes

FluoroCompounds

Pyridines

Pyridine

Pyridine series