ChemicalBook > CAS DataBase List > 3''-METHOXYOROBOL

3''-METHOXYOROBOL

Product Name: 3''-METHOXYOROBOL
CAS No.: 36190-95-1
Chemical Name: 3''-METHOXYOROBOL
Synonyms: -O-Methylorobol;3'-O-Methylorobol;3'-Methoxy-4',5,7-trihydroxyisoflavone;5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-
CBNumber: CB21484744
Molecular Formula: C16H12O6
Formula Weight: 300.26
MOL File: 36190-95-1.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: M269675
Product name: 3''-Methoxy-4'',5,7-trihydroxyisoflavone
Packaging: 10mg
Price: $210
Updated: 2021/12/16

AK Scientific

Product number: W1722
Product name: 3'-O-Methylorobol
Packaging: 10mg
Price: $181
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FO65483
Product name: Orobol-3'-methyl ether
Packaging: 25mg
Price: $195
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FO65483
Product name: Orobol-3'-methyl ether
Packaging: 5mg
Price: $61
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FO65483
Product name: Orobol-3'-methyl ether
Packaging: 10mg
Price: $97.5
Updated: 2021/12/16

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3''-METHOXYOROBOL Chemical Properties,Usage,Production

Uses

3''-Methoxy-4'',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2.

Definition

ChEBI: 3'-O-methylorobol is a hydroxyisoflavone that is orobol in which the hydroxy group at position 3' has been replaced by a methoxy group. It has been isolated from Crotalaria lachnophora. It has a role as a plant metabolite. It is a methoxyisoflavone and a hydroxyisoflavone. It is functionally related to an orobol.

3''-METHOXYOROBOL Preparation Products And Raw materials

Raw materials

Preparation Products

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36190-95-1, 3''-METHOXYOROBOLRelated Search:

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3'-Methoxy-4',5,7-trihydroxyisoflavone

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36190-95-1

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