ChemicalBook > CAS DataBase List > 3''-METHOXYOROBOL

3''-METHOXYOROBOL

Product Name
3''-METHOXYOROBOL
CAS No.
36190-95-1
Chemical Name
3''-METHOXYOROBOL
Synonyms
-O-Methylorobol;3'-Methoxy-4',5,7-trihydroxyisoflavone;5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-
CBNumber
CB21484744
Molecular Formula
C16H12O6
Formula Weight
300.26
MOL File
36190-95-1.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
M269675
Product name
3''-Methoxy-4'',5,7-trihydroxyisoflavone
Packaging
10mg
Price
$210
Updated
2021/12/16
AK Scientific
Product number
W1722
Product name
3'-O-Methylorobol
Packaging
10mg
Price
$181
Updated
2021/12/16
Biosynth Carbosynth
Product number
FO65483
Product name
Orobol-3'-methyl ether
Packaging
25mg
Price
$195
Updated
2021/12/16
Biosynth Carbosynth
Product number
FO65483
Product name
Orobol-3'-methyl ether
Packaging
5mg
Price
$61
Updated
2021/12/16
Biosynth Carbosynth
Product number
FO65483
Product name
Orobol-3'-methyl ether
Packaging
10mg
Price
$97.5
Updated
2021/12/16
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3''-METHOXYOROBOL Chemical Properties,Usage,Production

Uses

3''-Methoxy-4'',5,7-trihydroxyisoflavone is a derivative of Genistein (G350000); a compound that exhibits specific inhibitory activity against tyrosine kinases, including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2.

Definition

ChEBI: 3'-O-methylorobol is a hydroxyisoflavone that is orobol in which the hydroxy group at position 3' has been replaced by a methoxy group. It has been isolated from Crotalaria lachnophora. It has a role as a plant metabolite. It is a methoxyisoflavone and a hydroxyisoflavone. It is functionally related to an orobol.

3''-METHOXYOROBOL Preparation Products And Raw materials

Raw materials

Preparation Products

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36190-95-1, 3''-METHOXYOROBOLRelated Search:

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  • -O-Methylorobol
  • 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-
  • 3'-Methoxy-4',5,7-trihydroxyisoflavone
  • 5,7-Dihydroxy-3-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one
  • 36190-95-1
  • Miscellaneous Natural Products