ChemicalBook > CAS DataBase List > 5-Chloro-1-indanone

5-Chloro-1-indanone

Product Name
5-Chloro-1-indanone
CAS No.
42348-86-7
Chemical Name
5-Chloro-1-indanone
Synonyms
5-Chloro-2,3-dihydro-1H-inden-1-one;Chloro-1-indan;5-Chloro Indanone;5- chlorineindone;5-CHLORO-1-INDANONE;5-CHLOROINDAN-1-ONE;1-Indanone, 5-chloro-;5-Chloro-1-indanone,98%;5-Chloro-1-indanone,99%;5-Chloro-1-indanone >
CBNumber
CB2148511
Molecular Formula
C9H7ClO
Formula Weight
166.6
MOL File
42348-86-7.mol
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5-Chloro-1-indanone Property

Melting point:
94-98 °C (lit.)
Boiling point:
124-125 °C (3 mmHg)
Density 
1.1466 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
124-125°C/3mm
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly)
form 
Solid
color 
Light Beige to Beige
Water Solubility 
insoluble
BRN 
1448000
InChIKey
MEDSHTHCZIOVPU-UHFFFAOYSA-N
CAS DataBase Reference
42348-86-7(CAS DataBase Reference)
NIST Chemistry Reference
5-Chloro-1-indanone(42348-86-7)
EPA Substance Registry System
1H-Inden-1-one, 5-chloro-2,3-dihydro- (42348-86-7)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
433071
Product name
5-Chloro-1-indanone
Purity
99%
Packaging
5g
Price
$62.3
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
1g
Price
$65
Updated
2024/03/01
TCI Chemical
Product number
C1644
Product name
5-Chloro-1-indanone
Purity
>97.0%(GC)
Packaging
5g
Price
$212
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
1g
Price
$46.65
Updated
2024/03/01
Alfa Aesar
Product number
A18308
Product name
5-Chloro-1-indanone, 99%
Packaging
5g
Price
$180.65
Updated
2024/03/01
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5-Chloro-1-indanone Chemical Properties,Usage,Production

Chemical Properties

White Crystal

Uses

5-Chloro-1-indanone is the important intermediate of du pont company's new varieties of pesticides indoxacarb (popular name: indoxacarb), is also a kind of important medicine intermediate simultaneously.
5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.
5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors.

Uses

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Preparation

3-chlorobenzaldehyde as raw material first reacts with propionic acid to prepare 3-chloro-phenylpropionic acid, which is then subjected to Friedel-Crafts acylation reaction to prepare 5-chloro-1-indanone. Organic solvents of formic acid diethylamine participate in the first step, and the reaction temperature is 20-150℃. An organic solvent of methylene chloride and a catalyst of zinc chloride participate in the second step, and the reaction temperature is -10 to 80 ℃.
Synthetic method of 5-chloro-1-indanone

General Description

5-Chloro-1-indanone is a 5-halo-1-indanone. It participates in the Irie′s synthesis of substituted pyridines. 5-Chloro-1-indanone has a stable triclinic crystal structure and has intermolecular forces of C-H...O, C-H...Π, CO...Cl and Π...Π types.

5-Chloro-1-indanone Preparation Products And Raw materials

Raw materials

Preparation Products

Aprindine
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5-Chloro-1-indanone Suppliers

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View Lastest Price from 5-Chloro-1-indanone manufacturers

Hebei Mujin Biotechnology Co.,Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-30
Hebei Zhuanglai Chemical Trading Co Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-13
Hebei Weibang Biotechnology Co., Ltd
Product
5-Chloro-1-indanone 42348-86-7
Price
US $8.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28

42348-86-7, 5-Chloro-1-indanoneRelated Search:

Neosperidin dihydrochalcone cis-Octahydro-isoindole Chlormezanone 1-Indanone Hydrochlorothiazide 5-Chloro-2-indanone 7-CHLORO-1-INDANONE 5-Chloro-2-hydroxy-2-methoxycarbonyl-1-indanone Pigment Yellow 138 Difluorochloromethane TCID 4-Chloro-2-indanone 4-Chloro-1-Indanone INULIN Indan 6-Chloro-1-indanone 5-Chloroindole 5,7-Dichloro-2,3-dihydroinden-1-one

  • 5-chloro-2,3-dihydroinden-1-one
  • 5-Chloro-1-indanone,98%
  • 1-Indanone, 5-chloro-5- chlorineindon
  • 5 - chlorine indene ketone
  • Chloro-1-indan
  • 5-CHLORO-1-INDANONE
  • 5-CHLOROINDAN-1-INDANONE
  • 5-CHLOROINDAN-1-ONE
  • 1H-Inden-1-one, 5-chloro-2,3-dihydro-
  • 1-Indanone, 5-chloro-
  • 5-Chloro-2,3-dihydro-1H-inden-1-one
  • 5-Chloro-1-indanone,99%
  • 5-Chloro Indanone
  • 5- chlorineindone
  • 5-Chloro-1-indanone &gt
  • 1-Indanone,5-chloro- (7CI)
  • 2,3- dihydro -5- chloroindolone
  • Indoxacarb intermediate
  • 42348-86-7
  • C9H7OCl
  • Organic Building Blocks
  • Ketones
  • Building Blocks
  • Carbonyl Compounds
  • C9
  • Building Blocks
  • C9
  • Carbonyl Compounds
  • Carbonyl Compounds
  • Chemical Synthesis
  • Organic Building Blocks
  • Benzocycles
  • Indane/Indanone and Derivatives
  • Ketones
  • Indanone & Indene
  • 42348-86-7