ChemicalBook > CAS DataBase List > BOC-PHE-ONP

BOC-PHE-ONP

Product Name
BOC-PHE-ONP
CAS No.
7535-56-0
Chemical Name
BOC-PHE-ONP
Synonyms
BOC-PHE-ONP;Boc-L-Phe-ONp;BOC-PHENYLALANINE-ONP;BOC-PHE-ONP USP/EP/BP;Boc-Phe-(4-Nitrophenyl)OH;(Tert-Butoxy)Carbonyl Phe-ONp;Boc-L-phenylanine-4-nitropheny ester;BOC-L-PHENYLALANINE P-NITROPHENYL ESTER;BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER;N-Boc-L-Phenylalanine 4-nitrophenyl ester
CBNumber
CB2150048
Molecular Formula
C20H22N2O6
Formula Weight
386.4
MOL File
7535-56-0.mol
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BOC-PHE-ONP Property

Melting point:
127-128 °C
Boiling point:
558.4±50.0 °C(Predicted)
Density 
1.240±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
Crystalline Powder
pka
10.83±0.46(Predicted)
color 
White
Sensitive 
Moisture Sensitive
CAS DataBase Reference
7535-56-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
3-10-21
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
264826
Product name
Boc-L-phenylalanine 4-nitrophenyl ester
Packaging
25g
Price
$383
Updated
2021/12/16
TRC
Product number
B662045
Product name
Boc-Phe-ONP
Packaging
50mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
03807
Product name
Boc-L-phenylalanine 4-nitrophenyl ester
Purity
≥ 99% (HPLC)
Packaging
25G
Price
$45
Updated
2021/12/16
ChemScene
Product number
CS-M0809
Product name
4-Nitrophenyl(tert-butoxycarbonyl)-L-phenylalaninate
Packaging
1g
Price
$165
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
AAA0003689
Product name
BOC-PHE-ONP
Purity
95.00%
Packaging
25G
Price
$165.48
Updated
2021/12/16
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BOC-PHE-ONP Chemical Properties,Usage,Production

Uses

4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].

Synthesis

100-02-7

13734-34-4

7535-56-0

The general procedure for the synthesis of Boc-L-aniline-4-nitrophenyl ester from 4-nitrophenol and Boc-L-phenylalanine is as follows: dissolve N-tert-butoxycarbonyl-L-phenylalanine (50 g) in dichloromethane (800 ml), stirring until completely dissolved. P-nitrophenol (39 g), 4-dimethylaminopyridine (DMAP, 3 g) and dicyclohexylcarbodiimide (DCC, 39 g) were added and the reaction was carried out for 5 hours at about 20°C. After completion of the reaction, the reaction mixture was filtered and the filtrate was evaporated. Ethanol was added to the residue and heated until complete dissolution, then slowly cooled to 20-30°C to allow the solid to precipitate gradually. Water (50 ml) was added and the mixture was cooled to 0°C and crystallized for 1 hour. The solid was collected by filtration to afford the target product Boc-L-aniline-4-nitrophenyl ester (62 g, 86.5% yield, 93% purity).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-855. DOI:10.1080/10408398.2012.708368

BOC-PHE-ONP Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-PHE-ONP Suppliers

Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15402
Advantage
60
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Guangzhou Isun Pharmaceutical Co., Ltd
Tel
020-39119399 18927568969
Fax
020-39119999
Email
isunpharm@qq.com
Country
China
ProdList
4720
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9637
Advantage
58
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View Lastest Price from BOC-PHE-ONP manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-Phe-Onp 7535-56-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-15
Career Henan Chemical Co
Product
BOC-PHE-ONP 7535-56-0
Price
US $1.00/g
Min. Order
100g
Purity
>98%
Supply Ability
g/kg/Ton
Release date
2020-01-14

7535-56-0, BOC-PHE-ONPRelated Search:


  • N-TERT-BUTOXYCARBONYL-L-PHENYLALANINE-P-NITROPHENYL ESTER
  • 4-nitrophenyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoate
  • N-[(1,1-Dimethylethoxy)Carbonyl]-L-Phenylalanine 4-Nitrophenyl Ester
  • (Tert-Butoxy)Carbonyl Phe-ONp
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  • BOC-PHENYLALANINE-ONP
  • BOC-PHE-ONP
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  • Boc-Phe-(4-Nitrophenyl)OH
  • N-(tert-Butyloxycarbonyl)-L-phenylalanine 4-nitrophenyl ester
  • N-Boc-L-Phenylalanine 4-nitrophenyl ester
  • Boc-L-phenylanine-4-nitropheny ester
  • 4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate
  • L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-nitrophenyl ester
  • (4-nitrophenyl)(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoate
  • BOC-PHE-ONP USP/EP/BP
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  • BOC-4-Nitro-L-Phenylalanine Ethyl Ester extrapure, 98%
  • 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophenyl Ester)
  • N-Boc-L-phenylalanine p-nitrophenyl ester
  • 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophe
  • (S)-4-Nitrophenyl 2-(N-BOC-amino)-3-phenylpropanoate
  • 7535-56-0
  • 7536-56-0
  • Amino Acid Derivatives
  • Peptide Synthesis
  • Phenylalanine
  • Specialty Synthesis
  • Amino Acids