BOC-PHE-ONP
- Product Name
- BOC-PHE-ONP
- CAS No.
- 7535-56-0
- Chemical Name
- BOC-PHE-ONP
- Synonyms
- BOC-PHE-ONP;Boc-L-Phe-ONp;BOC-PHENYLALANINE-ONP;BOC-PHE-ONP USP/EP/BP;Boc-Phe-(4-Nitrophenyl)OH;(Tert-Butoxy)Carbonyl Phe-ONp;Boc-L-phenylanine-4-nitropheny ester;BOC-L-PHENYLALANINE P-NITROPHENYL ESTER;BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER;N-Boc-L-Phenylalanine 4-nitrophenyl ester
- CBNumber
- CB2150048
- Molecular Formula
- C20H22N2O6
- Formula Weight
- 386.4
- MOL File
- 7535-56-0.mol
BOC-PHE-ONP Property
- Melting point:
- 127-128 °C
- Boiling point:
- 558.4±50.0 °C(Predicted)
- Density
- 1.240±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- form
- Crystalline Powder
- pka
- 10.83±0.46(Predicted)
- color
- White
- Sensitive
- Moisture Sensitive
- CAS DataBase Reference
- 7535-56-0(CAS DataBase Reference)
Safety
- WGK Germany
- 3
- F
- 3-10-21
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 264826
- Product name
- Boc-L-phenylalanine 4-nitrophenyl ester
- Packaging
- 25g
- Price
- $383
- Updated
- 2021/12/16
- Product number
- B662045
- Product name
- Boc-Phe-ONP
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 03807
- Product name
- Boc-L-phenylalanine 4-nitrophenyl ester
- Purity
- ≥ 99% (HPLC)
- Packaging
- 25G
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-M0809
- Product name
- 4-Nitrophenyl(tert-butoxycarbonyl)-L-phenylalaninate
- Packaging
- 1g
- Price
- $165
- Updated
- 2021/12/16
- Product number
- AAA0003689
- Product name
- BOC-PHE-ONP
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $165.48
- Updated
- 2021/12/16
BOC-PHE-ONP Chemical Properties,Usage,Production
Uses
4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].
Synthesis
100-02-7
13734-34-4
7535-56-0
The general procedure for the synthesis of Boc-L-aniline-4-nitrophenyl ester from 4-nitrophenol and Boc-L-phenylalanine is as follows: dissolve N-tert-butoxycarbonyl-L-phenylalanine (50 g) in dichloromethane (800 ml), stirring until completely dissolved. P-nitrophenol (39 g), 4-dimethylaminopyridine (DMAP, 3 g) and dicyclohexylcarbodiimide (DCC, 39 g) were added and the reaction was carried out for 5 hours at about 20°C. After completion of the reaction, the reaction mixture was filtered and the filtrate was evaporated. Ethanol was added to the residue and heated until complete dissolution, then slowly cooled to 20-30°C to allow the solid to precipitate gradually. Water (50 ml) was added and the mixture was cooled to 0°C and crystallized for 1 hour. The solid was collected by filtration to afford the target product Boc-L-aniline-4-nitrophenyl ester (62 g, 86.5% yield, 93% purity).
References
[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-855. DOI:10.1080/10408398.2012.708368
BOC-PHE-ONP Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-PHE-ONP Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
- Tel
- --
- Fax
- --
- swiss@sennchem.com
- Country
- Switzerland
- ProdList
- 3143
- Advantage
- 71
View Lastest Price from BOC-PHE-ONP manufacturers
- Product
- Boc-L-Phe-Onp 7535-56-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2023-09-15
- Product
- BOC-PHE-ONP 7535-56-0
- Price
- US $1.00/g
- Min. Order
- 100g
- Purity
- >98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-01-14