ChemicalBook > CAS DataBase List > BOC-PHE-ONP

BOC-PHE-ONP

Product Name
BOC-PHE-ONP
CAS No.
7535-56-0
Chemical Name
BOC-PHE-ONP
Synonyms
BOC-PHE-ONP;Boc-L-Phe-ONp;BOC-PHENYLALANINE-ONP;BOC-PHE-ONP USP/EP/BP;Boc-Phe-(4-Nitrophenyl)OH;(Tert-Butoxy)Carbonyl Phe-ONp;Boc-L-phenylanine-4-nitropheny ester;BOC-L-PHENYLALANINE P-NITROPHENYL ESTER;BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER;N-Boc-L-Phenylalanine 4-nitrophenyl ester
CBNumber
CB2150048
Molecular Formula
C20H22N2O6
Formula Weight
386.4
MOL File
7535-56-0.mol
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BOC-PHE-ONP Property

Melting point:
127-128 °C
Boiling point:
558.4±50.0 °C(Predicted)
Density 
1.240±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
form 
Crystalline Powder
pka
10.83±0.46(Predicted)
color 
White
Sensitive 
Moisture Sensitive
CAS DataBase Reference
7535-56-0(CAS DataBase Reference)
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Safety

WGK Germany 
3
F 
3-10-21
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B662045
Product name
Boc-Phe-ONP
Packaging
50mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
264826
Product name
Boc-L-phenylalanine 4-nitrophenyl ester
Packaging
25g
Price
$383
Updated
2021/12/16
Chem-Impex
Product number
03807
Product name
Boc-L-phenylalanine 4-nitrophenyl ester
Purity
≥ 99% (HPLC)
Packaging
5G
Price
$12.5
Updated
2021/12/16
Chem-Impex
Product number
03807
Product name
Boc-L-phenylalanine 4-nitrophenyl ester
Purity
≥ 99% (HPLC)
Packaging
25G
Price
$45
Updated
2021/12/16
Iris Biotech GmbH
Product number
BAA5870
Product name
Boc-L-Phe-ONp
Packaging
5G
Price
$67.5
Updated
2021/12/16
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BOC-PHE-ONP Chemical Properties,Usage,Production

Uses

4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate is a phenylalanine derivative[1].

Synthesis

100-02-7

13734-34-4

7535-56-0

The general procedure for the synthesis of Boc-L-aniline-4-nitrophenyl ester from 4-nitrophenol and Boc-L-phenylalanine is as follows: dissolve N-tert-butoxycarbonyl-L-phenylalanine (50 g) in dichloromethane (800 ml), stirring until completely dissolved. P-nitrophenol (39 g), 4-dimethylaminopyridine (DMAP, 3 g) and dicyclohexylcarbodiimide (DCC, 39 g) were added and the reaction was carried out for 5 hours at about 20°C. After completion of the reaction, the reaction mixture was filtered and the filtrate was evaporated. Ethanol was added to the residue and heated until complete dissolution, then slowly cooled to 20-30°C to allow the solid to precipitate gradually. Water (50 ml) was added and the mixture was cooled to 0°C and crystallized for 1 hour. The solid was collected by filtration to afford the target product Boc-L-aniline-4-nitrophenyl ester (62 g, 86.5% yield, 93% purity).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-855. DOI:10.1080/10408398.2012.708368

BOC-PHE-ONP Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-PHE-ONP Suppliers

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View Lastest Price from BOC-PHE-ONP manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-L-Phe-Onp 7535-56-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-15
Career Henan Chemical Co
Product
BOC-PHE-ONP 7535-56-0
Price
US $1.00/g
Min. Order
100g
Purity
>98%
Supply Ability
g/kg/Ton
Release date
2020-01-14

7535-56-0, BOC-PHE-ONPRelated Search:

Aniline BOC-TYR-ONP N-Boc-L-Phenylalaninol BOC-ABU-ONP BOC-PHE-ONP BOC-L-ALANINE METHYL ESTER Phenylalanine-N-carboxylic acid dimethyl ester BOC-DL-PHENYLALANINE METHYL ESTER N-(tert-Butoxycarbonyl)-L-phenylalanine BOC-ALA-ONP BOC-GLY-ONP N-Boc-L-phenylalaninal 4-(3-phenylpropoxy)phenylamine BOC-O-BENZYL-L-TYROSINE 4-NITROPHENYL ESTER BOC-PHE-OME FOR-PHE-OME

  • N-TERT-BUTOXYCARBONYL-L-PHENYLALANINE-P-NITROPHENYL ESTER
  • 4-nitrophenyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoate
  • N-[(1,1-Dimethylethoxy)Carbonyl]-L-Phenylalanine 4-Nitrophenyl Ester
  • (Tert-Butoxy)Carbonyl Phe-ONp
  • (S)-4-Nitrophenyl2-((tert-butoxycarbonyl)amino)-3-phenylpropanoate
  • N-(tert-Butyloxycarbonyl)-L-phenylalanine p-nitrophenyl ester
  • Boc-L-phenylalanine 4-nitrophenyl ester≥ 99% (HPLC)
  • BOC-PHENYLALANINE-ONP
  • BOC-PHE-ONP
  • BOC-L-PHENYLALANINE 4-NITROPHENYL ESTER
  • BOC-L-PHENYLALANINE P-NITROPHENYL ESTER
  • 4-nitrophenyl N-(tert-butoxycarbonyl)-3-phenyl-L-alaninate
  • N-alpha-t-boc-L-phenylalanine-p-nitrophenylester,crystalline
  • n-alpha-t-boc-l-phenylalanine-p-nitrophenylestercrystalline
  • N-tert-Butoxycarbonyl-L-phenylalanine 4-nitrophenyl ester
  • Boc-L-Phe-ONp
  • N-alpha-t-Butyloxycarbonyl-L-phenylalanine p-nitrophenyl ester
  • N-(tert-butoxycarbonyl)-L-phenylalanine-4-nitrophenyl
  • Boc-Phe-(4-Nitrophenyl)OH
  • N-(tert-Butyloxycarbonyl)-L-phenylalanine 4-nitrophenyl ester
  • N-Boc-L-Phenylalanine 4-nitrophenyl ester
  • Boc-L-phenylanine-4-nitropheny ester
  • 4-Nitrophenyl (tert-butoxycarbonyl)-L-phenylalaninate
  • L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-, 4-nitrophenyl ester
  • (4-nitrophenyl)(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoate
  • BOC-PHE-ONP USP/EP/BP
  • Boc-l-phenylalanine 4-nitrophenyl ester, 98%+
  • BOC-4-Nitro-L-Phenylalanine Ethyl Ester extrapure, 98%
  • 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophenyl Ester)
  • N-Boc-L-phenylalanine p-nitrophenyl ester
  • 4-Nitrophenyl (2S)-2-(tert-Butoxycarbonylamino)-3-phenylpropanoate (N-BOC-L-Phenylalanine 4-Nitrophe
  • (S)-4-Nitrophenyl 2-(N-BOC-amino)-3-phenylpropanoate
  • 7535-56-0
  • 7536-56-0
  • Amino Acid Derivatives
  • Peptide Synthesis
  • Phenylalanine
  • Specialty Synthesis
  • Amino Acids