Capecitabine

Product Name: Capecitabine
CAS No.: 158798-73-3
Chemical Name: Capecitabine
Synonyms: Caxeta;Capiibine;Hsdb 7656;N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine;pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate;Pentyl N-[1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-2-oxo-pyrimidin-4-yl]carbamate;Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester
CBNumber: CB21503999
Molecular Formula: C15H22FN3O6
Formula Weight: 359.35
MOL File: 158798-73-3.mol

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Hazard and Precautionary Statements (GHS)

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Capecitabine Chemical Properties,Usage,Production

Originator

Xeloda,Hoffmann - La Roche Inc.,USA

Manufacturing Process

5-Deoxy-5-fluoro-N4-((n-pentyloxy)carbonyl)cytidine may be prepared according to US Patent No. 6,114,520.
From 2',3'-bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluorocytidine and n-pentylchloroformate in dichloromethane and pyridine may be obtained 2',3'- bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluoro-N4-((pentyloxy)carbonyl) cytidine.From 2',3'-bis-O-(tert-butyldimethylsilyl)-5'-deoxy-5-fluoro-N4- ((pentyloxy)carbonyl)cytidineand tetrabutylammonium fluoride in tetrahydrofuran at room temperature for 2 hours may be prepared the product which by hydrolyses may be converted to 5-deoxy-5-fluoro-N4- ((pentyloxy)carbonyl)cytidine. Purification of the product may be carried out by silica gel chromatography (using dichloromethane:methanol = 20:1 as an eluent).

Therapeutic Function

Antitumor

Capecitabine Preparation Products And Raw materials

Raw materials

Preparation Products

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Capecitabine Suppliers

China 17 United States 2 Global 19

Wisdom Pharmaceutical Co., Ltd.

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Credit Asia Chemical Co., Ltd.

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Hubei Kangbaotai Finechem Co., Ltd.

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Raw material medicin reagent co.,Ltd

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ShangHai Biochempartner Co.,Ltd

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Twochem Co.Ltd.

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Nanjing crow LuNing pharmaceutical technology co., LTD

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Tianjin Kaifu Pharmaceutical Technology Co., Ltd.

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NewCan Biotech Limited

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ANHUI WITOP BIOTECH CO., LTD

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Hefei TNJ Chemical Industry Co.,Ltd.

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Hubei xin bonus chemical co. LTD

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Suzhou Daolan Biomedical Technology Co., Ltd.

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View Lastest Price from Capecitabine manufacturers

Beijing Yibai Biotechnology Co., Ltd

Product: Capecitabine 158798-73-3
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99.0%
Supply Ability: 300kg/month
Release date: 2019-08-27

158798-73-3, CapecitabineRelated Search:

Cytosine CARBONYL SULFIDE Bensulfuron methyl Methyl salicylate 1,1'-Carbonyldiimidazole METSULFURON METHYL Kresoxim-methyl Thiophanate-methyl Fluorocytosine Methyl Carbonyl iron powder Fluorine Methyl bromide 5'-Deoxy-5-fluorocytidine 5-Fluorocytidine Capecitabine

N(4)-Pentyloxycarbonyl-5'-deoxy-5-fluorocytidine

Pentyl N-[1-[(2R,3R,4R,5R)-3,4-dihydroxy-5-methyl-oxolan-2-yl]-5-fluoro-2-oxo-pyrimidin-4-yl]carbamate

Capiibine

Carbamic acid, (1-(5-deoxy-beta-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinyl)-, pentyl ester

Caxeta

Hsdb 7656

pentyl N-[1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoro-2-oxopyrimidin-4-yl]carbamate

158798-73-3