ChemicalBook > CAS DataBase List > Anamorelin

Anamorelin

Product Name
Anamorelin
CAS No.
249921-19-5
Chemical Name
Anamorelin
Synonyms
CS-896;Rc 1291;ONO-7643;Alamorim;Anamoelin;anamorelin;Unii-dd5rba1nkf;Anamorelin (RC-1291);Anamorelin intemediate;Anamorelin (ONO 7643)
CBNumber
CB21518492
Molecular Formula
C31H42N6O3
Formula Weight
546.7
MOL File
249921-19-5.mol
More
Less

Anamorelin Property

Melting point:
132-134°C
Density 
1.214
storage temp. 
Refrigerator
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
16.22±0.46(Predicted)
color 
White to Off-White
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2519
Product name
Anamorelin
Purity
≥98% (HPLC)
Packaging
5 mg
Price
$75.2
Updated
2025/07/31
Sigma-Aldrich
Product number
SML2519
Product name
Anamorelin
Purity
≥98% (HPLC)
Packaging
25 mg
Price
$304
Updated
2025/07/31
Cayman Chemical
Product number
24676
Product name
Anamorelin
Purity
≥98%
Packaging
5mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
24676
Product name
Anamorelin
Purity
≥98%
Packaging
10mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
24676
Product name
Anamorelin
Purity
≥98%
Packaging
25mg
Price
$268
Updated
2024/03/01
More
Less

Anamorelin Chemical Properties,Usage,Production

Uses

Anamorelin functions as a novel therapeutic options for cachexia and sarcopenia. Cancer cachexia and clinical therapeutic interventions.

Biological Activity

Anamorelin is a non-peptidic ghrelin mimetic and growth hormone (GH) secretagogue. It is an orally-active, brain-penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). Anamorelin has been shown to increases appetite, overall body weight, lean body mass, and muscle strength in clinical studies with cancer patients suffering from cachexia.

in vivo

In rats, Anamorelin (ANAM) at an oral dose of 3, 10, or 30 mg/kg once daily significantly increases both food intake and body weight from Day 2 to Day 7 of treatment compared with the vehicle control. The cumulative change in food intake and weight gain increases dose-dependently, and these changes are significant at all dose levels (P<0.05) compared to the control. Administration of Anamorelin at a single oral dose of 3, 10, or 30 mg/kg induces a dose-dependent increase in plasma GH levels and GH AUC0-6h in rats[1].

Anamorelin Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

View Lastest Price from Anamorelin manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Anamorelin 249921-19-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Anamorelin 249921-19-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08
Zhuozhou Wenxi import and Export Co., Ltd
Product
Anamorelin 249921-19-5
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

249921-19-5, AnamorelinRelated Search:


  • anamorelin
  • (3R)-1-(2-Methylalanyl-D-tryptophyl)-3-(phenylmethyl)-3-piperidinecarboxylic acid 1,2,2-trimethylhydrazide
  • 3-Piperidinecarboxylic acid, 1-(2-methylalanyl-D-tryptophyl)-3-(phenylmethyl)-, trimethylhydrazide, (3R)-
  • Rc 1291
  • Unii-dd5rba1nkf
  • ONO-7643
  • Anamorelin (RC-1291)
  • (R)-1-((S)-2-((1H-indol-3-yl)methyl)-5-amino-5-methyl-4-oxohexanoyl)-3-benzyl-N,N',N'-trimethylpiperidine-3-carbohydrazide
  • Anamorelin intemediate
  • 5H-Pyrrolo[1,2-a]imidazole-2-carboxaldehyde,6,7-dihydro-(10CI)
  • 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide
  • Anamorelin(ONO-7643,RC-129)
  • Anamorelin (ONO 7643)
  • CS-896
  • RC-1291; ONO-7643; RC1291; ONO7643; RC 1291; ONO 7643
  • 3-Piperidinecarboxylic acid, 1-[(2R)-2-[(2-amino-2-methyl-1-oxopropyl)amino]-3-(1H-indol-3-yl)-1-oxopropyl]-3-(phenylmethyl)-, 1,2,2-trimethylhydrazide, (3R)-
  • Anamoelin
  • Alamorim
  • Anamorelin, 10 mM in DMSO
  • 2-amino-n-((r)-1-((r)-3-benzyl-3-(1,2,2-trimethylhydrazine-1-carbonyl)piperidin-1-yl)-3-(1h-indol-3-yl)-1-oxopropan-2-yl)-2-methylpropanamide
  • 249921-19-5
  • C31H42N6O3