3-Cyanoindole

ChemicalBook > CAS DataBase List > 3-Cyanoindole

Product Name: 3-Cyanoindole
CAS No.: 5457-28-3
Chemical Name: 3-Cyanoindole
Synonyms: NSC 24935;3-indole A;3-CYANOINDOLE;3-Indonylnitrile;3-Cyanoindole 98%;3-Cyanoindole ,98%;3-CYANOINDOLE (ICN);RARECHEM AH BS 0093;3-INDOLECARBONITRILE;INDOLE-3-CARBONITRILE
CBNumber: CB2157658
Molecular Formula: C9H6N2
Formula Weight: 142.16
MOL File: 5457-28-3.mol

Less

3-Cyanoindole Property

Melting point:: 179-182 °C (lit.)
Boiling point:: 249.72°C (rough estimate)
Density: 1.1777 (rough estimate)
refractive index: 1.6211 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 14.61±0.30(Predicted)
color: Orange to Brown
Water Solubility: Insoluble in water.
Sensitive: Air & Light Sensitive
BRN: 120888
CAS DataBase Reference: 5457-28-3(CAS DataBase Reference)
NIST Chemistry Reference: 3-Indolecarbonitrile(5457-28-3)

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39-36/37/39
RIDADR: 3439
WGK Germany: 3
HazardClass: 6.1
PackingGroup: III
HS Code: 29339900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

Less

N-Bromosuccinimide Price

Alfa Aesar

Product number: A16041
Product name: Indole-3-carbonitrile, 98%
Packaging: 1g
Price: $39.65
Updated: 2024/03/01

Alfa Aesar

Product number: A16041
Product name: Indole-3-carbonitrile, 98%
Packaging: 5g
Price: $132.65
Updated: 2024/03/01

Alfa Aesar

Product number: A16041
Product name: Indole-3-carbonitrile, 98%
Packaging: 25g
Price: $431
Updated: 2021/12/16

TRC

Product number: C987993
Product name: 3-Cyanoindole
Packaging: 50g
Price: $70
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC30372
Product name: 3-Cyanoindole
Packaging: 10g
Price: $80
Updated: 2021/12/16

Less

3-Cyanoindole Chemical Properties,Usage,Production

Chemical Properties

brown-grey to brown crystalline powder

Uses

3-Cyanoindole (cas# 5457-28-3) is a compound useful in organic synthesis.

Uses

Reactant for preparation of:

Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators
Inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities
4-substituted β-lactams
Biologically active Indoles
Inhibitors of glycogen synthase kinase 3β (GSK-3)
HIV-1 integrase inhibitors
Indole fragments as inosine monophosphate dehydrogenase (IMPDH) inhibitors
Aziridinomitosene skeleton
Potential antiviral agents

Reactant for:

Intramolecular oxidative C-H coupling reactions with applications in medium-ring synthesis techniques

Synthesis Reference(s)

Organic Syntheses, Coll. Vol. 5, p. 656, 1973
Tetrahedron, 50, p. 6549, 1994 DOI: 10.1016/S0040-4020(01)89685-X
Tetrahedron Letters, 18, p. 4417, 1977 DOI: 10.1016/S0040-4039(01)83524-3

General Description

3-Cyanoindole undergoes regiospecific bromination to afford 6-bromo-3-cyanoindole. 3-Cyanoindole is formed during the flash vacuum thermolysis (FVT) of 3-azidoquinoline.

3-Cyanoindole Preparation Products And Raw materials

Raw materials

Indole-3-carboxaldehyde Ammonium phosphate dibasic

Preparation Products

Less

3-Cyanoindole Suppliers

Belgium 4 Canada 1 China 220 Europe 2 France 1 Germany 7 India 22 Japan 2 Russia 1 Slovakia 1 Switzerland 4 United Kingdom 22 United States 50 Global 337

Zhanhua Huibang Chemical Co., Ltd.

Tel: 13906149256
Email: 793211102@qq.com
Country: China
ProdList: 117
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
Advantage: 69

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35896
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-82967028 13552068683
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12390
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9499
Advantage: 66

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11655
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8838
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18738
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Nanjing Vital Chemical Co., Ltd.

Tel: Please Send Email 18652950785
Fax: 025-87193546
Email: chemweiao@163.com
Country: China
ProdList: 4378
Advantage: 65

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 9387
Advantage: 52

Shanghai Shenyue Chemical Co., Ltd.

Tel: 021-021-52212593 18049974220
Fax: +86 (21) 51062076
Email: 2982497773@qq.com
Country: China
ProdList: 1622
Advantage: 60

Anhui Shite Pharmaceutical Technology Co., LTD

Tel: 0555-8228058 13621628489
Fax: 0512-63261912
Email: sales1@stepuppharm.com
Country: China
ProdList: 229
Advantage: 55

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.

Tel: 022-60116533 13207668525
Fax: 022-60979672
Email: saleskc@scipharmacn.com
Country: China
ProdList: 683
Advantage: 58

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Shanghai Topbiochem Technology Co., Ltd

Tel: +86-21-60341587
Fax: +86-21-61294319
Email: sales@topbiochem.com
Country: China
ProdList: 6175
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-400-6206333 18521732826
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9545
Advantage: 55

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

Shanghai Yolne Chemical Co., Ltd.

Tel: 021-62960152
Fax: 021-52212593
Email: 934678158@qq.com
Country: China
ProdList: 9899
Advantage: 55

Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
Advantage: 55

Wuxi Zhangkun Biochemical Technology Co., Ltd.

Tel: +86 0510-85629785
Fax: +86 0510-85625359
Country: China
ProdList: 2327
Advantage: 58

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Country: China
ProdList: 2930
Advantage: 58

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Suzhou Laing Biological Technology Co., LTD

Tel: 0512-62968256 18550502935
Fax: 0512-62968256
Email: export@laingbiotec.com
Country: China
ProdList: 1104
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai Aspire Biological Technology Co., Ltd.

Tel: 021-61317773
Fax: 021-61486878
Email: sales@aspirebio.com
Country: China
ProdList: 2880
Advantage: 58

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10276
Advantage: 55

SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.

Tel: 021-69106960 13701823733
Fax: 021-69106780
Email: 13701823733@163.com
Country: China
ProdList: 4767
Advantage: 60

Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.

Tel: 027-59420981,18702770802
Fax: 027-83322098
Country: China
ProdList: 1975
Advantage: 50

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Beijing Xinsavi Chemical Technology Co., Ltd.

Tel: 010-56218822 13717722232
Fax: 010-56218800
Email: xinsavichem@163.com
Country: China
ProdList: 3201
Advantage: 56

Shanghai Kaisai Chemical Co., Ltd

Tel: 021-33516722 13701817765
Fax: 021-33516776
Email: kaisaichem@163.com
Country: China
ProdList: 4741
Advantage: 58

Beijing HuaYangZhicheng Technology Co., Ltd.

Tel: 13716033033
Fax: 010-56276266
Email: hanchochem@163.com
Country: China
ProdList: 2960
Advantage: 50

Shanghai Rolead Chemical Technology Co., Ltd.

Tel: 021-69992220 13701886816
Fax: 021-69992237
Email: roleadchem@163.com
Country: China
ProdList: 4750
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

Less

View Lastest Price from 3-Cyanoindole manufacturers

Career Henan Chemical Co

Product: 3-Cyanoindole 5457-28-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: as request
Release date: 2018-12-24

5457-28-3, 3-CyanoindoleRelated Search:

p-Tolunitrile Indole-3-butyric acid 4-Nitrobenzonitrile 2-Methylindole Indole-3-carboxylic acid Indole-3-acetic acid 2-Cyanophenol Indometacin 2-Chloro-3-cyanopyridine Benzonitrile Indole Ethyl indole-3-carboxylate Indole-4-carboxaldehyde 6-CYANOINDOLE,CYANOINDOLE-6 4-CYANOINDOLE 1-BOC-5-CYANOINDOLE 7-CYANOINDOLE Carbonitrile

3-CYANOINDOLE

3-INDOLECARBONITRILE

1H-INDOLE-3-CARBONITRILE

RARECHEM AH BS 0093

INDOLE-3-CARBONITRILE

indoline-3-carbonitrile

Indole-3-carbonitrile,98%

3-Indonylnitrile

3-CYANOINDOLE (INDOLE-3-CARBONITRILE)

3-Cyanoindole ,98%

3-CYANOINDOLE (ICN)

3-indole A

NSC 24935

3-Cyanoindole 98%

1H-indole-3-carbonitrile(SALTDATA: FREE)

3-Cyanoindole pure, 98%

Indole-3-carbonitrile (6CI, 7CI, 8CI)

5457-28-3

C19H6N2

Building Blocks

Heterocyclic Building Blocks

Indoles

Pyrroles & Indoles

Indole

Indoles

Pharmaceutical Raw Materials

blocks

Carboxes

IndolesOxindoles

Indoles and derivatives

IndoleDerivative

bc0001