Alizapride
- Product Name
- Alizapride
- CAS No.
- 59338-93-1
- Chemical Name
- Alizapride
- Synonyms
- MS-5080;Litican;Plitican;Nausilen;Vergentan;ALIZAPRIDE;Alizapride CAS NO.59338-93-1;VergentanQ: What is Vergentan Q: What is the CAS Number of Vergentan;n-(1-allyl-2-pyrrolidinylmethyl)-6-methoxy-1h-benzotriazole-5-carboxamide;N-[(1-allylpyrrolidin-2-yl)methyl]-6-methoxy-2H-benzotriazole-5-carboxamide
- CBNumber
- CB2162373
- Molecular Formula
- C16H21N5O2
- Formula Weight
- 315.37
- MOL File
- 59338-93-1.mol
Alizapride Property
- Melting point:
- 139°
- Boiling point:
- 580.3±40.0 °C(Predicted)
- Density
- 1.224±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 7.09±0.40(Predicted)
- CAS DataBase Reference
- 59338-93-1(CAS DataBase Reference)
Safety
- Toxicity
- LD50 i.v. in mice (5 days): 92.7 mg/kg (Bulteau)
N-Bromosuccinimide Price
- Product number
- API0001412
- Product name
- ALIZAPRIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $780.15
- Updated
- 2021/12/16
- Product number
- API0001412
- Product name
- ALIZAPRIDE
- Purity
- 95.00%
- Packaging
- 1KG
- Price
- $7294.7
- Updated
- 2021/12/16
- Product number
- CM123074
- Product name
- N-((1-allylpyrrolidin-2-yl)methyl)-6-methoxy-1H-benzo[d][1,2,3]triazole-5-carboxamide
- Purity
- 95%
- Packaging
- 1g
- Price
- $327
- Updated
- 2021/12/16
- Product number
- CD31001364
- Product name
- Alizapride
- Purity
- 95+%
- Packaging
- 1g
- Price
- $620
- Updated
- 2021/12/16
- Product number
- MT-46749
- Product name
- Alizapride
- Purity
- 98%
- Packaging
- 10g
- Price
- $780
- Updated
- 2021/12/16
Alizapride Chemical Properties,Usage,Production
Originator
Plitican ,Delagrange ,France ,1981
Definition
ChEBI: 6-methoxy-N-[(1-prop-2-enyl-2-pyrrolidinyl)methyl]-2H-benzotriazole-5-carboxamide is a member of benzotriazoles.
Manufacturing Process
38.6 g (0.2 mol) of 2-methoxy-4,5-azimidobenzoic acid were dissolved in anhydrous toluene and 56 g (0.4 mol) of 1-allyl-2-amino-methylpyrrolidine were added. The mixture was heated to 50°C and then 42 g (0.3 mol) of phosphoric anhydride were added. The mixture was warmed at reflux temperature for 3 hours and then cooled to 80°C. After adding water, the aqueous layer was alkalized. The crystals were filtered, washed with water and then dissolved in 450 ml of acetone. After crystallization, the product was 40.4 g (yield 65%) of N-(1'-allyl-2'-pyrrolidylmethyl)-2-methoxy-4,5- azimidobenzamide having a melting point of 139°C were obtained.
Therapeutic Function
Neuroleptic, Antiemetic
Alizapride Preparation Products And Raw materials
Raw materials
Preparation Products
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