ChemicalBook > CAS DataBase List > H-TYR-D-ALA-GLY-PHE-D-LEU-OH

H-TYR-D-ALA-GLY-PHE-D-LEU-OH

Product Name: H-TYR-D-ALA-GLY-PHE-D-LEU-OH
CAS No.: 63631-40-3
Chemical Name: H-TYR-D-ALA-GLY-PHE-D-LEU-OH
Synonyms: YAGFL;DADLE;BW-180;BW-180C;BW-180C, 10 mM in DMSO;TYR-D-ALA-GLY-PHE-D-LEU;(D-ALA2,D-LEU5)-ENKEPHALIN;H-TYR-D-ALA-GLY-PHE-D-LEU-OH;Enkephalin, Leucine-2-Alanine;TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O
CBNumber: CB2167318
Molecular Formula: C29H39N5O7
Formula Weight: 569.65
MOL File: 63631-40-3.mol

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H-TYR-D-ALA-GLY-PHE-D-LEU-OH Property

Melting point:: >167°C (dec.)
Boiling point:: 991.9±65.0 °C(Predicted)
Density: 1.257±0.06 g/cm3(Predicted)
storage temp.: -15°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 3.40±0.10(Predicted)
form: Solid
color: White to Off-White
Water Solubility: Soluble to 1 mg/ml in water
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28928
Product name: DADLE
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 28928
Product name: DADLE
Packaging: 50mg
Price: $759
Updated: 2024/03/01

Cayman Chemical

Product number: 28928
Product name: DADLE
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 28928
Product name: DADLE
Packaging: 10mg
Price: $169
Updated: 2024/03/01

Tocris

Product number: 3790
Product name: DADLE
Packaging: 5
Price: $106
Updated: 2021/12/16

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H-TYR-D-ALA-GLY-PHE-D-LEU-OH Chemical Properties,Usage,Production

Uses

DADLE is a selective δ-?OR agonist.

in vivo

BW-180C ( [D-Ala2, D-Leu5]-Enkephalin; DADLE) protects liver against ischemia-reperfusion injury in the rat. DADLE (5 mg/kg) protects the heart, lung, and jejunum against ischemia-reperfusion (I-R) injury^[2].
BW-180C (DADLE) improves hepatic ischemia/reperfusion injury in mice via activation of the Nrf2/HO1 pathway^[3].
DADLE (5 mg/kg) significantly reduces the levels of alanine aminotransferase and aspartate aminotransferase in the serum, and the levels of malondialdehyde in the liver homogenate^[3].

Animal Model:	Male Wistar rats weighing 200 to 250 g^[2]
Dosage:	5 mg/kg
Administration:	Administered intravenously into the inferior vena cava
Result:	After 120 min of reperfusion, the serum GPT levels were significantly lower in the DADLE group than in the Control group.

Animal Model:	Male C57BL/6 mice (age, 35-42 days; weight, 18-22 g; 6 mice in each group)^[3]
Dosage:	5 mg/kg
Administration:	Injected intraperitoneally 15 min prior to I/R
Result:	The serum levels of AST and ALT in the serum DADLE group were significantly lower.

storage

Store at -20°C

H-TYR-D-ALA-GLY-PHE-D-LEU-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-TYR-D-ALA-GLY-PHE-D-LEU-OH Suppliers

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View Lastest Price from H-TYR-D-ALA-GLY-PHE-D-LEU-OH manufacturers

Career Henan Chemical Co

Product: H-TYR-D-ALA-GLY-PHE-D-LEU-OH 63631-40-3
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2020-02-18

63631-40-3, H-TYR-D-ALA-GLY-PHE-D-LEU-OHRelated Search:

Semaglutide PENTAGLYCINE H-HIS-LEU-OH [LEU5]-ENKEPHALIN GLYCYL-D-LEUCINE AC-D-NVA-OH TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT D-2-Amino-4-methylpentanoic acid GLY-GLY-D-LEU H-TYR-D-ALA-GLY-PHE-D-LEU-OH N-Acetyl-D-leucine (2-D-ALANINE-5-D-LEUCINE), [TYROSYL-3,-3H(N)]-

YAGFL

TYR-D-ALA-GLY-PHE-D-LEU

TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O

H-TYR-D-ALA-GLY-PHE-D-LEU-OH

(D-ALA2,D-LEU5)-ENKEPHALIN

[D-ALA2,D-LEU5]-ENKEPHALIN ACOH H2O

DADLE

Enkephalin, Leucine-2-Alanine

(D-Ala2,D-Leu5)-Enkephalinv MW :

2-D-Alanine-5-D-leucine-enkephalin

BW-180

(D-Ala2,D-Leu5)-Enkephalin H-Tyr-D-Ala-Gly-Phe-D-Leu-OH

D-Leucine, L-tyrosyl-D-alanylglycyl-L-phenylalanyl-

H-TYR-D-ALA-GLY-PHE-D-LEU-OH USP/EP/BP

L-Tyrosyl-D-Alanylglycyl-L-Phenylalanyl-D-Leucine

BW-180C

BW-180C,BW180C,Inhibitor,Opioid Receptor,inhibit,BW 180C

(D-Ala?,D-Leu?)-Enkephalin acetate salt

DADLE, delta-Opioid peptide agonist

BW-180C, 10 mM in DMSO

63631-40-3

peptide