ChemicalBook > CAS DataBase List > H-TYR-D-ALA-GLY-PHE-D-LEU-OH
H-TYR-D-ALA-GLY-PHE-D-LEU-OH
- Product Name
- H-TYR-D-ALA-GLY-PHE-D-LEU-OH
- CAS No.
- 63631-40-3
- Chemical Name
- H-TYR-D-ALA-GLY-PHE-D-LEU-OH
- Synonyms
- YAGFL;DADLE;BW-180;BW-180C;BW-180C, 10 mM in DMSO;TYR-D-ALA-GLY-PHE-D-LEU;(D-ALA2,D-LEU5)-ENKEPHALIN;H-TYR-D-ALA-GLY-PHE-D-LEU-OH;Enkephalin, Leucine-2-Alanine;TYR-D-ALA-GLY-PHE-D-LEU ACOH H2O
- CBNumber
- CB2167318
- Molecular Formula
- C29H39N5O7
- Formula Weight
- 569.65
- MOL File
- 63631-40-3.mol
More
Less
H-TYR-D-ALA-GLY-PHE-D-LEU-OH Property
- Melting point:
- >167°C (dec.)
- Boiling point:
- 991.9±65.0 °C(Predicted)
- Density
- 1.257±0.06 g/cm3(Predicted)
- storage temp.
- -15°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.40±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Water Solubility
- Soluble to 1 mg/ml in water
- Stability:
- Hygroscopic
More
Less
N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28928
- Product name
- DADLE
- Packaging
- 5mg
- Price
- $93
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28928
- Product name
- DADLE
- Packaging
- 50mg
- Price
- $759
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28928
- Product name
- DADLE
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28928
- Product name
- DADLE
- Packaging
- 10mg
- Price
- $169
- Updated
- 2024/03/01
Tocris
- Product number
- 3790
- Product name
- DADLE
- Packaging
- 5
- Price
- $106
- Updated
- 2021/12/16
More
Less
H-TYR-D-ALA-GLY-PHE-D-LEU-OH Chemical Properties,Usage,Production
Uses
DADLE is a selective δ-?OR agonist.
in vivo
BW-180C ( [D-Ala2, D-Leu5]-Enkephalin; DADLE) protects liver against ischemia-reperfusion injury in the rat. DADLE (5 mg/kg) protects the heart, lung, and jejunum against ischemia-reperfusion (I-R) injury[2].
BW-180C (DADLE) improves hepatic ischemia/reperfusion injury in mice via activation of the Nrf2/HO1 pathway[3].
DADLE (5 mg/kg) significantly reduces the levels of alanine aminotransferase and aspartate aminotransferase in the serum, and the levels of malondialdehyde in the liver homogenate[3].
| Animal Model: | Male Wistar rats weighing 200 to 250 g[2] |
| Dosage: | 5 mg/kg |
| Administration: | Administered intravenously into the inferior vena cava |
| Result: | After 120 min of reperfusion, the serum GPT levels were significantly lower in the DADLE group than in the Control group. |
| Animal Model: | Male C57BL/6 mice (age, 35-42 days; weight, 18-22 g; 6 mice in each group)[3] |
| Dosage: | 5 mg/kg |
| Administration: | Injected intraperitoneally 15 min prior to I/R |
| Result: | The serum levels of AST and ALT in the serum DADLE group were significantly lower. |
storage
Store at -20°C
H-TYR-D-ALA-GLY-PHE-D-LEU-OH Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
H-TYR-D-ALA-GLY-PHE-D-LEU-OH Suppliers
- Tel
- --
- Fax
- --
- spectrum@kv.ukrtel.net
- Country
- Ukraine
- ProdList
- 2741
- Advantage
- 53
More
Less
View Lastest Price from H-TYR-D-ALA-GLY-PHE-D-LEU-OH manufacturers
Career Henan Chemical Co
- Product
- H-TYR-D-ALA-GLY-PHE-D-LEU-OH 63631-40-3
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2020-02-18
63631-40-3, H-TYR-D-ALA-GLY-PHE-D-LEU-OHRelated Search:
Semaglutide
PENTAGLYCINE
H-HIS-LEU-OH
[LEU5]-ENKEPHALIN
GLYCYL-D-LEUCINE
AC-D-NVA-OH
TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
D-2-Amino-4-methylpentanoic acid
GLY-GLY-D-LEU
H-TYR-D-ALA-GLY-PHE-D-LEU-OH
N-Acetyl-D-leucine
(2-D-ALANINE-5-D-LEUCINE), [TYROSYL-3,-3H(N)]-