ChemicalBook > CAS DataBase List > 2-AMINO-N-METHYLBENZENESULFONAMIDE

2-AMINO-N-METHYLBENZENESULFONAMIDE

Product Name
2-AMINO-N-METHYLBENZENESULFONAMIDE
CAS No.
16288-77-0
Chemical Name
2-AMINO-N-METHYLBENZENESULFONAMIDE
Synonyms
N-Methyl-2-aminobenzenesulfonamide;2-AMINO-N-METHYLBENZENESULFONAMIDE;BenzenesulfonaMide, 2-aMino-N-Methyl-;2-aMino-N-Methylbenzene-1-sulfonaMide;2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)
CBNumber
CB2191047
Molecular Formula
C7H10N2O2S
Formula Weight
186.23
MOL File
16288-77-0.mol
More
Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Property

Melting point:
59-60℃
Boiling point:
352.9±44.0 °C(Predicted)
Density 
1.308
storage temp. 
2-8°C(protect from light)
pka
11?+-.0.10(Predicted)
Appearance
Light yellow to brown Solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TRC
Product number
A634700
Product name
2-Amino-N-methylbenzenesulfonamide
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA153547
Product name
2-Amino-N-methylbenzenesulfonamide
Packaging
1g
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-M2487
Product name
Benzenesulfonamide,2-amino-N-methyl-
Purity
>97.0%
Packaging
5g
Price
$98
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA153547
Product name
2-Amino-N-methylbenzenesulfonamide
Packaging
2g
Price
$100
Updated
2021/12/16
AK Scientific
Product number
W3551
Product name
2-Amino-N-methylbenzenesulfonamide
Packaging
5g
Price
$169
Updated
2021/12/16
More
Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Chemical Properties,Usage,Production

Description

2-Amino-N-methylbenzenesulfonamide is obtained by treating 2-nitrobenzenesulfonyl chloride with methylamine and subsequent reduction. Used as a dye component. The amides of 2-aminobenzenesulfonic acid can be treated with aldehydes or orthoformic acid esters to give 1,2,4-benzothiadiazine 1,1-dioxides or their dihydro compounds; these substances have been proposed as diuretics.

Synthesis

23530-40-7

16288-77-0

Step B / Intermediate C4: Synthesis of 2-amino-N-methylbenzenesulfonamide To a solution of N-methyl-2-nitrobenzenesulfonamide (26 g, 0.12 mol) in methanol (500 mL) was added 10% palladium carbon catalyst (2 g). The reaction mixture was stirred at room temperature under hydrogen atmosphere for 3 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 2-amino-N-methylbenzenesulfonamide (22 g, 98% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.45-7.48 (dd, 1H, J=1.6 Hz, 8.0 Hz), 7.24-7.31 (m, 2H), 6.81-6.83 (dd, 1H, J=0.6 Hz, 8.0 Hz), 6.60-6.65 (m, 1H), 5.89 (s 2H), 2.370-2.374 (d, 3H, J=1.6Hz).

References

[1] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 64
[2] Angewandte Chemie - International Edition, 2010, vol. 49, # 29, p. 4955 - 4957
[3] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 47
[4] Farmaco, Edizione Scientifica, 1954, vol. 9, p. 661,678, 680
[5] Farmaco, Edizione Scientifica, 1957, vol. 12, p. 495,499, 500

2-AMINO-N-METHYLBENZENESULFONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Suppliers

China 50 India 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 8 Global 63
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
D & O PHARMACHEM INC.
Tel
--
Fax
--
Email
info@dochem.com
Country
United States
ProdList
202
Advantage
51
More
Less

View Lastest Price from 2-AMINO-N-METHYLBENZENESULFONAMIDE manufacturers

Career Henan Chemical Co
Product
2-AMINO-N-METHYLBENZENESULFONAMIDE 16288-77-0
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-10

16288-77-0, 2-AMINO-N-METHYLBENZENESULFONAMIDERelated Search:

Chlorothiazide CYCLOTHIAZIDE DIAZOXIDE Althiazide HYDROFLUMETHIAZIDE Hydrochlorothiazide 2-Amino-N-ethylbenzenesulfonanilide POLYTHIAZIDE (200 MG) Trichlormethiazide BENDROFLUMETHIAZIDE BENZTHIAZIDE 7-(DIMETHYLAMINOSULPHONYL)-2,3-DIHYDRO-1-[[N-(2-METHOXYPHENYL)AMINO]CARBONYL]-(1H)-INDOLE (2-INDOL-3-YLETHYL)((2-NITROPHENYL)SULFONYL)AMINE 1-((4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)-2-NITROBENZENE 2-NITRO-1-((4-(5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)BENZENE 2,3-DIHYDRO-N,N-DIMETHYL-7-(1H)-INDOLESULPHONAMIDE 2-AMINO-N-QUINOLIN-8-YL-BENZENESULFONAMIDE 1-[(ETHYLAMINO)CARBONYL]-7-(DIMETHYLAMINOSULPHONYL)-2,3-DIHYDRO-(1H)-INDOLE

  • 2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)
  • N-Methyl-2-aminobenzenesulfonamide
  • 2-aMino-N-Methylbenzene-1-sulfonaMide
  • BenzenesulfonaMide, 2-aMino-N-Methyl-
  • 2-AMINO-N-METHYLBENZENESULFONAMIDE
  • 16288-77-0