ChemicalBook > CAS DataBase List > Cefozopran

Cefozopran

Product Name
Cefozopran
CAS No.
113359-04-9
Chemical Name
Cefozopran
Synonyms
D01052;Firstci;sce2787;SCE-1787;Firstcin);CEFOZOPRAN;Cefozopran (inn);SCE2787;SCE 2787;SCE-2787：Fastocin;Cefozopran(SCE 2787)
CBNumber
CB2198495
Molecular Formula
C19H17N9O5S2
Formula Weight
515.52
MOL File
113359-04-9.mol
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Cefozopran Property

Melting point:
>300°C
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
CAS DataBase Reference
113359-04-9(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H317May cause an allergic skin reaction

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific
Product number
H710
Product name
Cefozopran
Packaging
5g
Price
$590
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0001903
Product name
CEFOZOPRAN
Purity
95.00%
Packaging
10G
Price
$2243.59
Updated
2021/12/16
AHH
Product number
MT-49084
Product name
Cefozopran
Purity
98%
Packaging
0.5g
Price
$910
Updated
2021/12/16
DC Chemicals
Product number
DC8067
Product name
Cefozopran(SCE2787)
Purity
>98%
Packaging
250mg
Price
$1000
Updated
2021/12/16
Crysdot
Product number
CD31004510
Product name
Cefozopran
Purity
98+%
Packaging
50mg
Price
$122
Updated
2021/12/16
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Cefozopran Chemical Properties,Usage,Production

Chemical Properties

White To Pale-Yellow Powder

Uses

Antibacterial

Definition

ChEBI: Cefozopran is a fourth-generation cephalosporin antibiotic having imidazo[1,2-b]pyridazin-1-ium-1-ylmethyl and [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It is a cephalosporin, a member of thiadiazoles and an imidazopyridazine.

Antimicrobial activity

An aminothiazole cephalosporin formulated as the hydrochloride. Activity is similar to that of ceftazidime, but it is more active against methicillin-susceptible staphylococci (MIC 1 mg/L). Representative MICs against Gram-negative species are: Esch coli 0.25 mg/L; K. pneumoniae 1 mg/L; Ps. aeruginosa 1–8 mg/L. Activity against Acinetobacter spp., Sten. maltophilia and B. fragilis group is poor.
A 20-min infusion of 1.5 g achieved a plasma concentration of around 125 mg/L at the end of infusion. Almost 90% of the dose was excreted in the urine over 24 h. The mean terminal half-life was around 2 h. Adverse reactions appear to be typical of those of other group 6 cephalosporins.
It is available in Japan.

Cefozopran Preparation Products And Raw materials

Raw materials

2-Mercapto-5-methyl-1,3,4-thiadiazole Hexane Potassium iodide 2-Butanone Trifluoroacetic acid Pyridazine Phosphorus pentachloride Ethyl acetate Dichloromethane Formamide

Preparation Products

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Cefozopran Suppliers

Canada 1 China 84 Europe 3 Germany 1 India 2 South Korea 1 United Kingdom 4 United States 18 Global 114
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113359-04-9, CefozopranRelated Search:

Thioacetamide N-Acetyl-L-cysteine Acetyl coenzyme A sodium salt Acetamide Acetylacetone 6-Aminocaproic acid ALTRENOGEST Glycine Acetyl chloride N,N-Dimethylacetamide Tris(hydroxymethyl)aminomethane DIACETAMIDE Cefazolin 2,1,3-Benzothiadiazole Acetaminophen 2-Mercapto-5-methyl-1,3,4-thiadiazole Cefotetan 1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium inner salt

  • CEFOZOPRAN
  • sce2787
  • SCE2787;SCE 2787
  • Cefozopran(SCE 2787)
  • 1-[[(6R,7R)-7-[[(2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-imidazo[1,2-b]pyridazinium hydroxide inner salt
  • 1-[[(6R,7R)-7-[[2Z)-(5-Amino-1,2,4-thiadiazol-3-yl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]imidazo[1,2-b]pyridazinium Inner Salt
  • Firstci
  • SCE-1787
  • Cefozopran (inn)
  • D01052
  • Firstcin)
  • SCE-2787：Fastocin
  • (6R,7R)-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-methoxyiminoacetyl]amino]-3-(imidazo[2,3-f]pyridazin-4-ium-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Parent nucleus of Cefozopran
  • Cefozopran USP/EP/BP
  • 113359-04-9
  • C19H17N9O5S2
  • C19H18ClN9O5S2
  • Antibacterial
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Cefozopran Hydrochloride and its intermediates