ChemicalBook > CAS DataBase List > ARGIPRESSIN ACETATE

ARGIPRESSIN ACETATE

Product Name: ARGIPRESSIN ACETATE
CAS No.: 129979-57-3
Chemical Name: ARGIPRESSIN ACETATE
Synonyms: AVP;AC-AVP;AC[ARG8]VASOPRESSIN;ARGIPRESSIN ACETATE;Argipressine acetate;[Arg8]Vasopressin TFA;Acetate fine vasopressin;[Arg8]Vasopressin acetate;[8-ARG]VASOPRESSIN ACETATE;BETA-HYPOPHAMINE ACETATE SALT
CBNumber: CB2205623
Molecular Formula: C48H69N15O14S2
Formula Weight: 1144.28
MOL File: 129979-57-3.mol

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ARGIPRESSIN ACETATE Property

Melting point:: 189 °C(dec.)
storage temp.: −20°C
solubility: Water: 1 mg/ml
form: powder to crystal
color: White to Light yellow
Water Solubility: Water: 1 mg/ml

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Safety

Hazard Codes: Xn
Risk Statements: 20
Safety Statements: 36
WGK Germany: 3
F: 3-10
HS Code: 2937.19.0000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical

Product number: V0159
Product name: [Arg 8]-Vasopressin Acetate
Packaging: 5MG
Price: $178
Updated: 2025/07/31

TCI Chemical

Product number: V0159
Product name: [Arg 8]-Vasopressin Acetate
Packaging: 25MG
Price: $536
Updated: 2025/07/31

Cayman Chemical

Product number: 24154
Product name: Argipressin (acetate)
Purity: ≥95%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Usbiological

Product number: 354139
Product name: AVP
Packaging: 48Tests
Price: $588
Updated: 2021/12/16

Chem-Impex

Product number: 38359
Product name: [Arg8]-Vasopressinacetate,≥98%(HPLC)
Purity: ≥98%(HPLC)
Packaging: 5MG
Price: $287.71
Updated: 2021/12/16

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ARGIPRESSIN ACETATE Chemical Properties,Usage,Production

Description

Argipressin is a peptide hormone with vasoconstrictive and antidiuretic activities that binds to the vascular arginine vasopressin receptor, V₁, with K_d values of 1.31 and 1.44 nM in A₇r₅ rat aortic smooth muscle cells and neonatal rat cardiomyocytes, respectively. It also stimulates the intracellular release of calcium in A₇r₅ cells (EC₅₀ = 5 nM). In rat models, argipressin induces hypertension and tachycardia when injected into the lateral septal nuclei at a dose of 100-400 ng and increases heart rate and mean arterial pressure (MAP) when injected into the medial amygdaloid body at a dose of 150-600 ng.

Uses

Argipressin (Arg8-vasopressin) (acetate) binds to the V1, V2, V3-vascular arginine vasopressin receptor, with a Kd value of 1.31 nM in A7r5 rat aortic smooth muscle cells for V1[1][2][3][4].

in vivo

Argipressin (Arg8-vasopressin) (acetate) (25 nmol/kg bw; intraperitoneal injection; once) significantly reduces overall AUC glucose values, but not increases insulin levels in mice^[1].

Animal Model:	NIH Swiss mice (adult; male; 12-14weeks)^[1]
Dosage:	25 nmol/kg bw
Administration:	AVP (25 nmol/kg bw; intraperitoneal injection; once)
Result:	Reduced (P<0.001) overall AUC glucose values，but not increased insulin levels in mice.

References

[1] Shruti Mohan, et al. Vasopressin receptors in islets enhance glucose tolerance, pancreatic beta-cell secretory function, proliferation and survival. Biochimie. DOI:10.1016/j.biochi.2019.01.008
[2] Thibonnier M, et al. Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Endocrinology. 1991 Dec;129(6):2845-56. DOI:10.1210/endo-129-6-2845
[3] Moriya T, et al. Vasopressin-induced intracellular Ca2? concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Res. 2012 Nov 5;1483:1-12. DOI:10.1016/j.brainres.2012.08.028
[4] Keun Suk Park, et al. Role of vasopressin in current anesthetic practice. Korean J Anesthesiol. 2017 Jun; 70(3): 245–257. DOI:10.4097/kjae.2017.70.3.245

ARGIPRESSIN ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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129979-57-3, ARGIPRESSIN ACETATERelated Search:

Carbetocin Felypressin Pramlintide acetate PENTAGASTRIN Terlipressin acetate Lypressin Ornipressin Argipressine Desmopressin acetate Desmopressin CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG

(CYS-TYR-PHE-GLN-ASN-CYS)CYCL-PRO-ARG-GLY-NH2 ACETATE SALT

CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2 ACETATE SALT

ANTIDIURETIC HORMONE ACETATE SALT

ARGIPRESSIN ACETATE

ARGININE VASOPRESSIN ACETATE SALT

[ARG8]-VASOPRESSIN ACETATE SALT

BETA-HYPOPHAMINE ACETATE SALT

AVP

AC-CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2

AC-AVP

AC[ARG8]VASOPRESSIN

[8-ARGININE]VASOPRESSIN ACETATE

[8-ARG]VASOPRESSIN ACETATE

[Arg8]Vasopressin acetate

[8-Arginine]Vasopressin acetate, Argipressin acetate, AVP

Argipressine acetate

Acetate fine vasopressin

[Arg8]Vasopressin TFA

Argipressin Acetate, (Arg9)-Vasopressin

Argipressine acetate USP/EP/BP

Vasopressin, 8-L-arginine-, acetate (1:)

129979-57-3

freepeptide

C46H65N15O12S2C2H4O2