1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

Description Reference

Product Name: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
CAS No.: 887144-97-0
Chemical Name: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent
Synonyms: Togni Reagent;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole;1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole;togni's reagent;3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole;3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole;1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b;1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)-;3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole;3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 95%
CBNumber: CB22101080
Molecular Formula: C10H10F3IO
Formula Weight: 330.09
MOL File: 887144-97-0.mol

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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Property

Melting point:: 75-79 °C
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: powder
color: white to off-white
Stability:: Moisture Sensitive
InChIKey: HVAPLSNCVYXFDQ-UHFFFAOYSA-N

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37
RIDADR: 1325
WGK Germany: 3
TSCA: No
HazardClass: 4.1
PackingGroup: Ⅲ
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 696641
Product name: 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Purity: 95%
Packaging: 5g
Price: $342
Updated: 2024/03/01

Sigma-Aldrich

Product number: 696641
Product name: 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Purity: 95%
Packaging: 1g
Price: $442
Updated: 2024/03/01

TCI Chemical

Product number: T2624
Product name: 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole
Purity: >97.0%(HPLC)
Packaging: 1g
Price: $221
Updated: 2024/03/01

TCI Chemical

Product number: T2624
Product name: 1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole
Purity: >97.0%(HPLC)
Packaging: 5g
Price: $767
Updated: 2024/03/01

Sigma-Aldrich

Product number: 696641
Product name: 3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Purity: 95%
Packaging: 250mg
Price: $71.4
Updated: 2024/03/01

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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Chemical Properties,Usage,Production

Description

1,3-dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole is in the form of colorless, white solid. It is soluble in all common organic solvents. It is used as effective and very versatile reagent for trifluoromethylation reactions of a variety of compounds including secondary and primary aryland alkylphospines, phenols, peptides containing cysteine residues by SPPS and electrophilic S-trifluoromethylation, arenes and N-heterocycles, and electrophilic N-trifluoromethylation of arozoles.

Reference

J. Charpentier, N. Früh, A. Togni, Electrophilic Trifluoromethylation by use of hypervalent iodine reagents, Chemical Reviews, 2015, vol. 115, pp. 650-682

Chemical Properties

White to light yellow solid

Uses

Mild, electrophilic, hypervalent iodine CF3 reagent effective for the trifluoromethylation of a wide range of substrates.

Uses

Togni’s Reagent is used in trifluoromethylation reactions.

reaction suitability

reaction type: C-C Bond Formation

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Preparation Products And Raw materials

Raw materials

Preparation Products

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1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent Suppliers

China 153 India 4 Japan 1 Switzerland 1 United Kingdom 2 United States 12 Global 173

Shanghai AmasPharm Co., Ltd.

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TCI (Shanghai) Development Co., Ltd.

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Energy Chemical

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View Lastest Price from 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 887144-97-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-09

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 887144-97-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent 887144-97-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

887144-97-0, 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis ReagentRelated Search:

(Difluoromethyl)bis(2,5-dimethylphenyl)sulfonium Tetrafluoroborate 1-TrifluoroMethyl-1,2-benziodoxol-3(1H)-one (PERFLUORO-N-HEXYL)PHENYLIODONIUM TRIFLUOROMETHANESULFONATE Pyrazine Lactic acid N,N-Dimethylacetamide N,N-Dimethylaniline Diphenyl(trifluoromethyl)sulfonium trifluoromethanesulfonate 2,2,2-trifluoroethyl(phenyl)iodonium trifluoromethanesulfonate diphenyl(2,2,2-trifluoroethyl)sulfanium trifluoromethanesulfonate (perfluoroethyl)diphenylsulfonium trifluoromethanesulfonate Mesityl(2,2,2-trifluoroethyl)iodonium trifluoromethanesulfonate (difluoromethyl)(2,4-dimethylphenyl)(phenyl)sulfonium tetrafluoroborate Iodonium, (1,1,2,2,3,3,4,4,4-nonafluorobutyl)phenyl-,1,1,1-trifluoromethanesulfonate (2,2-difluoroethyl)diphenylsulfonium trifluoromethanesulfonate 2-IODOISOPROPYLBENZENE Trifluoromethyl iodide 1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, Tognis Reagent

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole

1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole

1,3-dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole

1,3-Dhydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-benziodoxole

3,3-DMethyl-1-(trifluoroMethyl)-1,2-benziodoxole

1,3-Dihydro-3,3-diMethyl-1-(trifluoroMethyl)-1,2-b

3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole 95%

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole / TOGNI A

1,2-Benziodoxole,3,3-dimethyl-1-(trifluoromethyl)-

Togni Reagent

3,3-DiMethyl-1-(trifluoroMethyl)-1,2-benziodoxole (Togni‘s reagent)

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole, >=98%

3,3-Dimethyl-1-(trifluoromethyl)-1,2- benziodoxole (Togni's reagent I)

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benzodioxole

1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole, 97%, for synthesis

3,3-dimethyl-1-(trifluoromethyl)-1$l^{3},2-benziodoxole

3,3-dimethyl-1-(trifluoromethyl)-1λ3,2-benziodoxole

Togni`s Reagent (3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole) extrapure, 97%

togni's reagent

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole (ACI)

887144-97-0

C10H10F3IO