5-Pyrimidinemethanol

Product Name: 5-Pyrimidinemethanol
CAS No.: 25193-95-7
Chemical Name: 5-Pyrimidinemethanol
Synonyms: RARECHEM AK ML 0566;5-pyrimidinemethanol;5-Pyrimidinylmethanol;Pyrimidine-5-methanol;PYRIMIDIN-5-YLMETHANOL;5-(HYDROXYMETHYL)PYRIMIDINE;5-(Hydroxymethyl)pyrimidi...;5-Pyrimidinemethanol (7CI,9CI);5-(Hydroxymethyl)pyrimidine 97%;(PYRIMIDIN-5-YL)METHANOL,PURITY
CBNumber: CB2211431
Molecular Formula: C5H6N2O
Formula Weight: 110.11
MOL File: 25193-95-7.mol

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5-Pyrimidinemethanol Property

Melting point:: 51-52 °C
Boiling point:: 250.8±15.0 °C(Predicted)
Density: 1.227±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 13.43±0.10(Predicted)
color: Yellow
CAS DataBase Reference: 25193-95-7(CAS DataBase Reference)

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

H317May cause an allergic skin reaction

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P997320
Product name: 5-Pyrimidinemethanol
Packaging: 500mg
Price: $105
Updated: 2021/12/16

TRC

Product number: P997320
Product name: 5-Pyrimidinemethanol
Packaging: 5g
Price: $725
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-Q7
Product name: 5-(Hydroxymethyl)pyrimidine
Purity: 97%
Packaging: 250mg
Price: $29
Updated: 2021/12/16

Frontier Specialty Chemicals

Product number: CAPOP12793
Product name: (Pyrimidin-5-yl)methanol
Purity: 95%
Packaging: 1g
Price: $38
Updated: 2021/12/16

Matrix Scientific

Product number: 068525
Product name: 5-Pyrimidinemethanol
Purity: >95%
Packaging: 1g
Price: $50
Updated: 2021/12/16

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5-Pyrimidinemethanol Chemical Properties,Usage,Production

Uses

5-?Pyrimidinemethanol is a reagent used in the synthesis of melanin-concentrating hormone receptor 1 antagonists.Also used in the preparation of annulated 5-aryl-substituted pyridines.

Synthesis

10070-92-5

25193-95-7

Step 3. Synthesis of 5-pyrimidinemethanol. 5-Pyrimidinecarboxaldehyde (2 g, 18.50 mmol, 1.00 eq.) and sodium borohydride (2 g) were dissolved in methanol (100 mL) and the reaction was stirred for 30 min at 0-10 °C. Upon completion of the reaction, the solvent was removed by vacuum concentration and the resulting residue was purified by silica gel column chromatography with dichloromethane/methanol (50:1, v/v) as eluent to give 1.2 g (59% yield) of the target compound 5-pyrimidine methanol as a light yellow solid. Mass spectrometry result: m/z = 111.0 [M + H]+.

References

[1] Patent: WO2013/130935, 2013, A1. Location in patent: Paragraph 0218
[2] Patent: WO2013/19621, 2013, A1. Location in patent: Page/Page column 41
[3] Journal of Organic Chemistry, 2000, vol. 65, # 26, p. 9261 - 9264
[4] Patent: WO2009/45381, 2009, A1. Location in patent: Page/Page column 29-30
[5] Patent: WO2009/45386, 2009, A1. Location in patent: Page/Page column 32-33

5-Pyrimidinemethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Pyrimidinemethanol Suppliers

China 139 Czech Republic 1 Europe 1 Germany 2 India 1 United Kingdom 2 United States 14 Global 160

RihaChem

Tel: --
Fax: --
Email: info@rihachem.com
Country: Czech Republic
ProdList: 258
Advantage: 54

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View Lastest Price from 5-Pyrimidinemethanol manufacturers

Dideu Industries Group Limited

Product: 5-Pyrimidinemethanol 25193-95-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons
Release date: 2022-02-16

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Pyrimidine methanol 25193-95-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 5-Pyrimidine methanol 25193-95-7
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

25193-95-7, 5-PyrimidinemethanolRelated Search:

Silver sulfadiazine 5-Fluorouracil Sulfadiazine Fluorocytosine Uracil Methanol Pyrimidine Cytosine METHYL PYRIMIDINE-5-CARBOXYLATE ETHYL 5-PYRIMIDINECARBOXYLATE 98 ETHYL 2-AMINO-4-PROPYLPYRIMIDINE-5-CARBOXYLATE 2-AMINO-5-CARBOETHOXY-4-HYDROXYPYRIMIDINE 5-CARBOXYCYTOSINE 5-Hydroxymethyluracil 4-AMINOPYRIMIDINE-5-CARBOXYLIC ACID ETHYL 2-AMINO-4-METHYLPYRIMIDINE-5-CARBOXYLATE ETHYL 2-AMINO-4-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 5-CARBETHOXY-2-THIOURACIL

RARECHEM AK ML 0566

PYRIMIDIN-5-YLMETHANOL

5-pyrimidinemethanol

5-(HYDROXYMETHYL)PYRIMIDINE

5-Pyrimidinemethanol (7CI,9CI)

(PYRIMIDIN-5-YL)METHANOL,PURITY:95% MIN(HPLC)

5-(Hydroxymethyl)pyrimidi...

(PYRIMIDIN-5-YL)METHANOL,PURITY

5-(Hydroxymethyl)pyrimidine 97%

5-Pyrimidinemethanol ISO 9001：2015 REACH

5-Pyrimidinylmethanol

Pyrimidine-5-methanol

25193-95-7

pharmacetical

Heterocycle-Pyrimidine series

PYRIMIDINE