ChemicalBook > CAS DataBase List > 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether

Product Name
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether
CAS No.
16627-68-2
Chemical Name
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether
Synonyms
1,1,2,2-TETRAFLUOROETHYL 2,2,3,3-TETRAFLUOROPROPYL ETHER;1,1,2,2-tetrafluoro-3-(1,1,2,2-tetrafluoroethoxy)propane;uoropropyL;DAIKIN T-5216;HFE458 HFE-458;1,1,2,2-TetrafL;2,2,3,3-tetrafL;HYDROFLUOROETHER-458;2-Tetrafluoroethyl-2;3-tetrafluoropropylether
CBNumber
CB2214179
Molecular Formula
C5H4F8O
Formula Weight
232.07
MOL File
16627-68-2.mol
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1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Property

Boiling point:
92 °C
Density 
1.533
refractive index 
1.29
Flash point:
27.5 °C
storage temp. 
Sealed in dry,Room Temperature
form 
clear liquid
Specific Gravity
1.533
color 
Colorless to Almost colorless
InChI
InChI=1S/C5H4F8O/c6-2(7)4(10,11)1-14-5(12,13)3(8)9/h2-3H,1H2
InChIKey
HCBRSIIGBBDDCD-UHFFFAOYSA-N
SMILES
C(F)(F)C(F)(F)COC(F)(F)C(F)F
CAS DataBase Reference
16627-68-2(CAS DataBase Reference)
EPA Substance Registry System
(2H-Perfluoroethyl)(1H,1H,3H-perfluoropropyl)ether (16627-68-2)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
RIDADR 
3271
HazardClass 
IRRITANT
PackingGroup 
II
HS Code 
29091990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H226Flammable liquid and vapour

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
T3069
Product name
1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
Purity
>98.0%(GC)
Packaging
5g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
T3069
Product name
1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
Purity
>98.0%(GC)
Packaging
25g
Price
$57
Updated
2024/03/01
Frontier Specialty Chemicals
Product number
JK246778
Product name
1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
Packaging
5g
Price
$68
Updated
2021/12/16
Oakwood
Product number
010635
Product name
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether
Packaging
100g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
5332AD
Product name
1,1,2,2-Tetrafluoroethyl 2,2,3,3-Tetrafluoropropyl Ether
Packaging
25g
Price
$79
Updated
2021/12/16
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1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Chemical Properties,Usage,Production

Description

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether (HFE-458) is a hydrofluoroether. Hydrofluoroether is a new type of  chlorofluorocarbons (CFCs) substitute, ODP is zero, GWP is low, and the atmospheric residence time is very short. It is considered as one of the ideal substitutes for CFCs.

Uses

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and chemical production processes.

Synthesis


A system of a 6-L autoclave made of stainless steel was evacuated. The autoclave was charged with 401 g of potassium hydroxide (7.15 mol, 0.55 molar amount relative to 1 mol of a fluorine-containing alkyl alcohol), water (1604 mL), 2,2,3,3-tetrafluoro-1-propanol (boiling point of 109?? C., specific gravity of 1.4) represented by HCF2CF2CH2OH (1716 g, 13 mol) as a fluorine-containing alkyl alcohol. Then, the system was evacuated and replaced with nitrogen 20 times at room temperature. After evacuated, the system was filled with tetrafluoroethylene to 0.1 MPa, and the reaction system was heated to 85?? C. After the temperature in the system reached 85?? C., tetrafluoroethylene was added thereto little by little so that the reaction pressure was kept at 0.5 to 0.8 MPa. The temperature in the system was adjusted so as to be kept at 75 to 95?? C.Tetrafluoroethylene was added until the amount reached 0.5 molar relative to 1 mol of the fluorine-containing alkyl alcohol. The reaction was continuously carried out under stirring. When reduction in the pressure in the autoclave was stopped, the temperature in the autoclave was reduced to room temperature and unreacted tetrafluoroethylene was discharged, and the reaction was stopped. These steps took 5 hours to perform.The fluoroether of a lower phase of the production solution was HCF2CF2CH2OCF2CF2H (boiling point of 92?? C., specific gravity of 1.52). Table 1 shows the composition of the fluoroether production solution of a lower phase resulting from GC analysis.

1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether Suppliers

Hubei Wande Chemical Co., Ltd
Tel
027-59210159 15377098680
Fax
027-59210159
Email
1148280011@qq.com
Country
China
ProdList
9959
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58
Yangzhou modier Electronic Materials Co., Ltd
Tel
0514-82098883; 13761402923
Email
market@modeltemol.com
Country
China
ProdList
910
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58
Shangfluoro
Tel
021-65170832 17301729617
Email
qinba_2@163.com
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China
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269
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58
Jinan Guochen Taifu Chemical Co., Ltd
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0531-88162029 13256661585
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0531-88162019
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guochentaifu@126.com
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China
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Wuhan Silworld Chemical Co.,Ltd
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027-85613400 15827173649
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027-85613419
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info@silworldchemical.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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021-61259108 18621169109
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86-21-61259102
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market03@meryer.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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24529
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Beijing HwrkChemical Technology Co., Ltd
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010-89508211 18501085097
Fax
010-89508210
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sales.bj@hwrkchemical.com
Country
China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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sales8178@energy-chemical.com
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China
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View Lastest Price from 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether manufacturers

Shenzhen Huayi Brothers Technology Co.,Ltd
Product
1,1,2,2-tetrafluoroethyl-2,3,3-tetrafluoropropane ether HFE-458 16627-68-2
Price
US $0.00-0.00/kg
Min. Order
25kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-11-19
Hebei Chuanghai Biotechnology Co,.LTD
Product
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether 16627-68-2
Price
US $100.00-50.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-20
Hebei Mojin Biotechnology Co.,Ltd
Product
1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether 16627-68-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-08-13

16627-68-2, 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyletherRelated Search:


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  • 2H-Tetrafluoroethyl 2,2,3,3-tetrafluoropropyl ether
  • HYDROFLUOROETHER(HFE-458)
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  • 1,1,2,2-tetrafluoro-3-(1,1,2,2-tetrafluoroethoxy)propane
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  • 1,1,2,2-TetrafL
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  • 1,1,2,2-Tetrafluoroethyl-2,2,3,3-Tetrafluoropropylether,>98%
  • 2-Tetrafluoroethyl-2
  • 3-tetrafluoropropylether
  • HFE458 HFE-458
  • 1,1,2,2-tetrafluoroethyl-2,3,3-tetrafluoropropane ether HFE-458
  • 16627-68-2