ChemicalBook > CAS DataBase List > Dimethyl fluoromalonate

Dimethyl fluoromalonate

Product Name
Dimethyl fluoromalonate
CAS No.
344-14-9
Chemical Name
Dimethyl fluoromalonate
Synonyms
METHYL 2-FL;DIMETHYL FLUOROMALONATE;Dimethyl 2-fluoromalonate;Dimethylfluoromalonate97%;Dimethyl fluoromalonate 97%;fluoro-malonicaciddimethyles;imethyl2-fluoropropanedioate;Dimethyl 2-fluoromalonate 97%;Dimethyl 2-fluoropropanedioate;fluoro-malonicaciddimethylester
CBNumber
CB2216739
Molecular Formula
C5H7FO4
Formula Weight
150.11
MOL File
344-14-9.mol
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Dimethyl fluoromalonate Property

Boiling point:
76 °C
Density 
1.4g/ml
refractive index 
1.4032
Flash point:
111-112°C/45mm
pka
10.35±0.46(Predicted)
form 
solid
color 
Colourless to off-white / liquid
BRN 
1768414
CAS DataBase Reference
344-14-9(CAS DataBase Reference)
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Safety

Hazard Codes 
T,C
Risk Statements 
34
Safety Statements 
26-36/37/39-45-23 2636/37/3945-20
RIDADR 
3265
Hazard Note 
Toxic
HazardClass 
8
PackingGroup 
II
HS Code 
29171900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Alfa Aesar
Product number
L16751
Product name
Dimethyl fluoromalonate, 97%
Packaging
1g
Price
$67.65
Updated
2024/03/01
Alfa Aesar
Product number
L16751
Product name
Dimethyl fluoromalonate, 97%
Packaging
5g
Price
$232.65
Updated
2024/03/01
TRC
Product number
D465743
Product name
Dimethylfluoromalonate
Packaging
500mg
Price
$65
Updated
2021/12/16
TRC
Product number
D465743
Product name
Dimethylfluoromalonate
Packaging
100mg
Price
$45
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK250144
Product name
Dimethylfluoromalonate
Purity
98%
Packaging
1g
Price
$58
Updated
2021/12/16
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Dimethyl fluoromalonate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

Dimethyl 2-fluoromalonate is used as an intermediate in organic synthesis.

Preparation

synthesis of dimethyl 2-fluoromalonate: Dimethyl malonate (19.8 g, 0.15 mol) and Cu(NO3)2·2.5H2O (3.50 g, 15 mmol) were dissolved in acetonitrile (85 mL), the mixture was cooled to 0–5 °C and stirred at 650 rpm using an overhead stirrer. After purging the system with N2 for 5 minutes, fluorine gas (20% v/v in N2, 50 mL min-1 , 170 mmol) was introduced into the reaction mixture for 7 h. After purging with nitrogen for 20 minutes, the solvent was removed in vacuo and the residue was partitioned between water (30 mL) and ethyl acetate (20 mL). The aqueous phase was extracted with ethyl acetate (2 × 20 mL) and the combined organic layer was washed with saturated brine (20 mL). After drying over sodium sulphate, the solvent was evaporated under reduced pressure to give dimethyl 2-fluoromalonate (21.8 g, 97% yield, 95% purity) as a colourless oil;
IR (neat, cm-1 ) 2962, 1748, 1438, 1250, 1206, 1112, 1016; δH (CDCl3, 400 MHz) 3.85 (6H, s, CH3), 5.31 (1H, d, 2 JHF 48.0, CHF); δF (CDCl3, 376 MHz): -195.73 (d, 2 JHF 48.0, CH–F); δC (CDCl3, 100 MHz) 53.48 (CH3), 85.19 (d, 1 JCF 197.2, C–F), 164.39 (d, 2 JCF 24.0, CvO); m/z (EI+ ) 150 (3%, [M]+ ), 119 (42%, [M-OMe]+ ), 91 (73%, [M-COOMe]+ ), 59 (100%, [COOMe]+ ).

Dimethyl fluoromalonate Preparation Products And Raw materials

Raw materials

Preparation Products

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Dimethyl fluoromalonate Suppliers

China 182 France 1 Germany 2 India 2 Italy 1 United Kingdom 10 United States 19 Global 217
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View Lastest Price from Dimethyl fluoromalonate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Dimethyl fluoromalonate 344-14-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09
Zhuozhou Wenxi import and Export Co., Ltd
Product
Dimethyl fluoromalonate 344-14-9
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Career Henan Chemical Co
Product
Dimethyl fluoromalonate 344-14-9
Price
US $1.80-3.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
88KG
Release date
2019-09-04

344-14-9, Dimethyl fluoromalonateRelated Search:

Diisopropyl malonate Xylene 2,2-DIMETHYL-MALONIC ACID DIMETHYL ESTER DIMETHYL METHOXYMALONATE N,N-Dimethylformamide Dimethyl sulfoxide Dimethyl sulfate Dimethyl methylmalonate Diethyl methylmalonate ETHANE Dimethyl phthalate Dacthal Dimethyl chloromalonate Dimethyl malonate Diethyl malonate Dimethyl carbonate Malonic acid Dimethyl isobutylmalonate

  • 2-FLUORO-MALONIC ACID DIMETHYL ESTER
  • 2-FLUORO-4-METHOXYACETOACETIC ACID METHYL ESTER
  • Dimethyl 2-fluoromalonate 97%
  • BUTYRIC ACID, 2-FLUORO-3-OXO-4-METHOXY-, METHYL ESTER
  • DIMETHYL FLUOROMALONATE
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  • METHYL 2-FLUORO-4-METHOXYACETOACETATE
  • fluoro-malonicaciddimethylester
  • Dimethyl fluoromalonate 97%
  • Dimethylfluoromalonate97%
  • fluoro-malonicaciddimethyles
  • METHYL 2-FL
  • Dimethyl 2-fluoropropanedioate
  • Propanedioic acid, 2-fluoro-, 1,3-dimethyl ester
  • imethyl2-fluoropropanedioate
  • 2-fluoro-Propanedioic acid 1,3-dimethyl ester
  • 2-Fluoro-malonic acid 1,3-dimethyl ester
  • 344-14-9
  • C3H3FO4
  • C6H9FO4
  • C5H7FO4
  • Small molecule
  • API intermediates