ChemicalBook > CAS DataBase List > (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate

Product Name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
CAS No.
125995-13-3
Chemical Name
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
Synonyms
ATS-9;(4R,6R)-T-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE;2-diMethyl-1;Atorvastatin A9;3-dioxane-4-acetate;Atorvastatin Impurity Ⅱ;Atorvastatin calcium-10;Atorvastatin Impurity 83;Atarvostatin intermediate;ATROVASTATIN INTERMEDIATES
CBNumber
CB2218182
Molecular Formula
C14H27NO4
Formula Weight
273.37
MOL File
125995-13-3.mol
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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Property

Boiling point:
339.8±17.0 °C(Predicted)
Density 
0.992±0.06 g/cm3(Predicted)
refractive index 
1.454-1.456
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Chloroform
pka
9.80±0.10(Predicted)
form 
Viscous Liquid
color 
Light yellow to green or light blue
λmax
204nm(EtOH)(lit.)
InChIKey
HWSHVKNLMBMKSR-GHMZBOCLSA-N
CAS DataBase Reference
125995-13-3(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29153900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B3702
Product name
tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Purity
>98.0%(GC)
Packaging
1g
Price
$32
Updated
2024/03/01
TCI Chemical
Product number
B3702
Product name
tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
Purity
>98.0%(GC)
Packaging
5g
Price
$96
Updated
2024/03/01
TRC
Product number
C497250
Product name
(4R,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging
50mg
Price
$65
Updated
2021/12/16
Chem-Impex
Product number
39604
Product name
tert-Butyl2-[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate,98%(GC)
Purity
98%(GC)
Packaging
1G
Price
$25.76
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD22376
Product name
(4R,cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane-4-acetate
Packaging
10g
Price
$54
Updated
2021/12/16
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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Chemical Properties,Usage,Production

Description

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an impurity of Atorvastatin. Atorvastatin is a drug used to lower cholesterol levels in the blood. It belongs to a class of drugs called HMG-CoA reductase inhibitors, and it works by blocking an enzyme that plays a role in the production of cholesterol.

Chemical Properties

Colorless to light yellow liqui

Uses

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate is an useful synthetic intermediate.

Uses

An impurity of Atorvastatin (A791750).

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Chemical Trading Co., Ltd.
Tel
--
Fax
--
Email
sales@tci-chemical-trading.com
Country
Japan
ProdList
597
Advantage
58
FUJIFILM Wako Pure Chemical Corporation
Tel
--
Fax
--
Email
ffwk-cservice@fujifilm.com
Country
Japan
ProdList
6222
Advantage
58
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View Lastest Price from (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $30.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
3000kg
Release date
2024-03-22
Henan Fengda Chemical Co., Ltd
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22
R&D Scientific Inc.
Product
(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate 125995-13-3
Price
US $850.00/Kg
Min. Order
1Kg
Purity
98
Supply Ability
500 Kg
Release date
2024-02-21

125995-13-3, (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetateRelated Search:


  • (4R,CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R-Cis)-1,1-Dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxoane-4-acetate
  • (4R,6R)-T-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • (4R,6R)-TERT-BUTYL-6-(2-AMINOETHYL)-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • ATS-9
  • (4R-CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE (ATS-9)
  • Atorvastatin Intermediate Ⅰ
  • Atorvastatin Intermediate 1
  • ATROVASTATIN INTERMEDIATES
  • (4R-Cia)-1,1-dimethyl ethyl-6-cyano methyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,Cis)-1,1-Dimethylethyl-6-(2-Aminoethyl)-2,2-Dimethyl-1,3-Dioxane-4-Acetate
  • (4R-cis)-1,1-dimethylethyl-6-aminoethyl- 2,2-dimethyl-1,3-dloxane-4-acetate
  • (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-Dioxane-4-acetic acid, 1,1-dimethylethyl ester
  • TERT-BUTYL[(4R,6R)-6-(2-AMINOETHYL)-2,2-DIMETHYL-1, 3-DIOXAN-4-YL]ACETATE
  • ATS-9 (4R, cis)C1,1-dimethylethyl-6-aminoethyl-2,2-dimethyl-1,3-dioxane C4-Acetate
  • (4R, 6R)-6-(2aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-Butyl Ester
  • <i>tert</i>-Butyl 2-[(4<i>R</i>,6<i>R</i>)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • (4R, 6R)-6-(2aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-Butyl Easter
  • (4R,6R)-Tert-Butyl-6-(2-Aminoe
  • ATS 9 (4R,CIS)-1,1-DIMETHYLETHYL-6-AMINOETHYL-2,2-DIMETHYL-1,3-DIOXANE-4-ACETATE
  • TERT-BUTYL 2-((4R,6S)-6-(AMINOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE
  • (4R-Cis)-1,1-dimethylethyl-6-aminomethyl-2,2-dimethyl-1,3-dio-cxane-acetate
  • Atorvastatin Impurity Ⅱ
  • Atorvastatin intermediatesAts-9
  • Atorvastatin calcium-10
  • Atorvastatin Impurity 83
  • tert-butyl [(4R,6R)-6-aminoethyl-2,2-dimethyl-1,3-dioxan-4-yl]acetate
  • tert-Butyl 6-aminoethyl-2,2-dimethyl-1,3-dioxolane-4-acetate
  • (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate,95%
  • 2-diMethyl-1
  • 3-dioxane-4-acetate
  • 6R)-tert-Butyl-6-(2-aMinoethyl)-2
  • (4<i>R</i>,6<i>R</i>)-<i>tert</i>-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • 1,3-Dioxane-4-acetic acid, 6-(2-aminoethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6R)-
  • 4R,6R)-tert-Butyl-6-(2-aMinoethyl)-2,2-diMethyl-1
  • (4R,Cis)-1,1-diMethylethyl6-aMinoethyl
  • 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid tert-Butyl Ester
  • 2-[6-(2-AMinoethyl)-2,2-diMethyl-1,3-dioxan-4-yl]-3,3-diMethylbutanoate
  • 1,1-Dimethylethyl (4R-cis)-6-Aminoe
  • tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate &gt
  • (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3- dioxane-4-acetate(A9)
  • ATORVASTATIN A9 (4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • (4R,6R)-t-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-...
  • 2-[(4R,6R)-2,2-dimethyl-6-[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,3-dioxan-4-yl]ethylazanium
  • Atorvastatin Intermediate A9
  • 1,1-Dimethylethyl (4R-cis)-6-Aminoethyl-2,2-dimethyl-1,3-dio
  • tert-Butyl 2-((4R,6R)-6-aminoethyl-2,2- dimethyl-1,3-dioxane-4-yl)acetate
  • 1,1-Dimethylethyl (4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
  • Atorvastatin calcium impurity 18
  • Atarvostatin intermediate
  • tert-Butyl 2-[(4R,6R)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetate, ≥ 98.0%
  • Atorvastatin A9
  • 125995-13-3
  • C14H28NO4
  • C14H27NO4
  • Amines
  • Chiral Reagents
  • Inhibitors