(3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one
- Product Name
- (3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one
- CAS No.
- 40456-50-6
- Chemical Name
- (3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one
- Synonyms
- Yatei;Yatein;YatapoxvirusYatein;(+)-Deoxypodorhizon;(-)-Deoxypodorhizone;(-)-Deoxypodorhizone;Yatein/deoxypodorhizone;(-)-trans-3-(3,4-Methylenedioxybenzyl)-2-(3,4,5-trimethoxybenzyl)butyrolactone;(3R,4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(3,4,5-trimethoxyphenyl)methyl]oxolan-2-one;(3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one
- CBNumber
- CB22190075
- Molecular Formula
- C22H24O7
- Formula Weight
- 400.42
- MOL File
- 40456-50-6.mol
(3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one Property
- Boiling point:
- 564.9±45.0 °C(Predicted)
- Density
- 1.266±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- A solid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- 29766
- Product name
- Yatein
- Packaging
- 500μg
- Price
- $153
- Updated
- 2024/03/01
- Product number
- 29766
- Product name
- Yatein
- Packaging
- 1mg
- Price
- $290
- Updated
- 2024/03/01
- Product number
- W1872
- Product name
- Yatein
- Packaging
- 1mg
- Price
- $421
- Updated
- 2021/12/16
- Product number
- CFN98635
- Product name
- Yatein
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $463
- Updated
- 2021/12/16
- Product number
- CD32001467
- Product name
- Yatein
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $730
- Updated
- 2021/12/16
(3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one Chemical Properties,Usage,Production
Description
Yatein is a lignan that has been found in C. formosana and has diverse biological activities. It inhibits the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 1 μM). Yatein inhibits herpes simplex virus 1 (HSV-1) replication in a plaque reduction assay (IC50 = 30.6 μM). It induces apoptosis and production of reactive oxygen species (ROS) in, and is cytotoxic to, A549 and CL1-5 non-small cell lung cancer (NSCLC) cells (IC50s = 3.5 and 1.9 μM, respectively). Yatein inhibits aggregation of rabbit platelets induced by platelet-activating factor (PAF), collagen, or arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) in a concentration-dependent manner.
Definition
ChEBI: A member of the class of butan-4-olides carrying 3,4,5-trimethoxybenzyl and (1,3-benzodioxol-5-yl)methyl substituents at positions 3 and 4 respectively.
(3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one Preparation Products And Raw materials
Raw materials
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View Lastest Price from (3R)-3α-(3,4,5-Trimethoxybenzyl)-4β-(1,3-benzodioxole-5-ylmethyl)tetrahydrofuran-2-one manufacturers
- Product
- Yatein 40456-50-6
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥96%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-05-12