ChemicalBook > CAS DataBase List > Methyl 4-chloropicolinate

Methyl 4-chloropicolinate

Product Name
Methyl 4-chloropicolinate
CAS No.
24484-93-3
Chemical Name
Methyl 4-chloropicolinate
Synonyms
4-CHLORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER;METHYL 4-CHLOROPYRIDINE-2-CARBOXYLATE;4-chloropicolinate;EOS-62380;IFLAB-BB F2108-0101;oro-2-pyridinecarboxyL;Methyl 4-chloropicolite;METHYL 4-CHLOROPICOLINATE;4-chloropyridine-2-formate;Methyl 4-Chloro-2-picolinate
CBNumber
CB2224066
Molecular Formula
C7H6ClNO2
Formula Weight
171.58
MOL File
24484-93-3.mol
More
Less

Methyl 4-chloropicolinate Property

Melting point:
50-52
Boiling point:
105-111 °C(Press: 2-3 Torr)
Density 
1.294±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
-0.25±0.10(Predicted)
color 
Off-White to Beige
InChI
InChI=1S/C7H6ClNO2/c1-11-7(10)6-4-5(8)2-3-9-6/h2-4H,1H3
InChIKey
VTENWIPSWAMPKI-UHFFFAOYSA-N
SMILES
C1(C(OC)=O)=NC=CC(Cl)=C1
CAS DataBase Reference
24484-93-3(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36
Safety Statements 
26
HazardClass 
IRRITANT
HS Code 
2933399990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
ADE000348
Product name
4-Chloro-pyridine-2-carboxylic acid methyl ester
Purity
Aldrich
Packaging
1g
Price
$209
Updated
2024/03/01
TCI Chemical
Product number
M1832
Product name
Methyl 4-Chloro-2-pyridinecarboxylate
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
M1832
Product name
Methyl 4-Chloro-2-pyridinecarboxylate
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$38
Updated
2024/03/01
TRC
Product number
M294455
Product name
Methyl4-Chloropicolinate
Packaging
1g
Price
$60
Updated
2021/12/16
Usbiological
Product number
M3396-85
Product name
Methyl 4-Chloropicolinate
Packaging
1g
Price
$333
Updated
2021/12/16
More
Less

Methyl 4-chloropicolinate Chemical Properties,Usage,Production

Chemical Properties

Brown Solid

Uses

Methyl 4-Chloropicolinate (cas# 24484-93-3) is a compound useful in organic synthesis.

Production Methods

The starting material 2-picolinic acid was treated with SOCl2 to generate 4-chloropicolinoyl chloride, and then esterification with MeOH resulted in the formation of methyl 4-chloropicolinate.

Synthesis Reference(s)

Synthetic Communications, 26, p. 2017, 1996 DOI: 10.1080/00397919608003557

Synthesis

To a suspension of 4-chloropyridine-2-carboxylic acid (4.5 g, 29.0 mmol) in methylene chloride (120 mL) was added oxalyl chloride (3.0 mL, 1.2 eq) under Ar2. The reaction was cooled to 0° C., and 500 uL of DMF was added. A large amount of gas was generated in situ. The reaction was stirred at room temperature for 1.5 h and then concentrated. Dry MeOH (50 mL) was added to the crude acyl chloride residue. The reaction was stirred at room temperature for 0.5 h, then quenched with NaHCO3 (5%) to neutral, extracted with EtOAc, and washed with brine. The combined organics were dried over MgSO4, filtered, and concentrated in vacuo to give 5.0 g of a crude solid, which was triturated with 5% EtOAc/hexane to give Methyl 4-chloropicolinate as a light yellow solid (4.5 g, 90%).

Methyl 4-chloropicolinate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Methyl 4-chloropicolinate Suppliers

Americas 1 Canada 2 China 405 Europe 1 France 1 Germany 3 India 23 Japan 1 Slovakia 2 Sweden 1 Switzerland 2 The Netherlands 1 United Kingdom 6 United States 33 Global 482
Beijing DeLee Pharma Technology Co.,Ltd.
Tel
010-69322287 17316103847
Email
704067151@qq.com
Country
China
ProdList
269
Advantage
58
Lianyungang Shenghe Biotechnology Co., Ltd.
Tel
0518-87108777 13585296001
Email
haizaofu@163.com
Country
China
ProdList
43
Advantage
58
Beijing Jianuode Pharmaceutical Technology Co., Ltd.
Tel
010-67267894 18611880885
Email
gianord@163.com
Country
China
ProdList
32
Advantage
58
NanJing Xienuo bio Co.,Ltd.
Tel
025-84112752 13805181430
Fax
+86-25-84846489
Email
154301870@qq.com
Country
China
ProdList
1000
Advantage
55
Tianjin Englon Technology Co., LTD
Tel
010-010-1234567 17526513758
Email
2062435649@qq.com
Country
China
ProdList
97
Advantage
49
Shanghai Hope Chem Co., Ltd.，
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
476
Advantage
55
Shanghai Toplab Chemical Co., Ltd.
Tel
021-31137757-00; 18121466954
Fax
021-64902762
Country
China
ProdList
172
Advantage
55
Chengda Pharmaceuticals Co., LTD.
Tel
0573-84185927 18367305117;
Email
scarlett.zhu@chengdapharm.com
Country
China
ProdList
68
Advantage
58
Wuhan EnTai Technology Development Co,.Ltd
Tel
86-27-82330560
Fax
86-27-82330547
Email
2536851935@qq.com
Country
China
ProdList
347
Advantage
69
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Liaoning Tianhua Chemical Co., Ltd.
Tel
0418-6530555 2855550
Fax
+86-418-6502885
Country
China
ProdList
338
Advantage
69
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
future industrial shanghai co., ltd
Tel
400-0066400 13621662912
Fax
021-55660885
Email
sales@jonln.com
Country
China
ProdList
1995
Advantage
65
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
Advantage
66
Shangchem Co., Ltd.
Tel
+86-21-68182121
Fax
+86-21-68182121
Country
China
ProdList
882
Advantage
52
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9810
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5691
Advantage
66
PSN Pharmaceutical Technology Co., Ltd.
Tel
86-25-57062118
Fax
86-25-57065896
Email
sales@jspsn.com
Country
China
ProdList
496
Advantage
57
Beijing HengPuGao Pharmaceutical Chemistry Technology Co., Ltd.
Tel
010-81520996 13439320863
Fax
010-81520996
Email
hengpugao@126.com
Country
China
ProdList
159
Advantage
57
Shanghai Ennopharm Co., Ltd.
Tel
+86 (21) 6435-5022
Country
China
ProdList
4267
Advantage
65
Chengdu Green Young Biomedical Technology Co., Ltd.
Tel
86+28-85337952 18081025021
Fax
86+28-85337952
Email
greenyoung@glykj.com
Country
China
ProdList
94
Advantage
62
skychemical Co.Ltd
Tel
021-20958197 20965099
Fax
021-20960837
Email
sales@skychemical.com
Country
China
ProdList
1183
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
SpringPharma Tech Co.,Ltd
Tel
+86-25-68710855, +86-25-68710897
Fax
025-68710856
Email
sales@springpharma.net
Country
China
ProdList
1261
Advantage
62
Wuhan Arike Technology Co., Ltd.
Tel
027- 51832457 94518350
Fax
E-Mail Inquiry
Country
China
ProdList
746
Advantage
62
Shanghai Sphchem Co., Ltd.
Tel
021-56491756 13512199871
Fax
021-5649-1756
Email
2819742715@qq.com
Country
China
ProdList
4001
Advantage
55
Wuhan ariel chemical Co., LTD.
Tel
18986259541 18986259541
Fax
027-87840182
Email
sales@3stc.com
Country
China
ProdList
4007
Advantage
58
Heterochem
Tel
027-88041443 13072715837
Fax
027-51829379
Email
sales@hetero-chem.com
Country
China
ProdList
696
Advantage
58
Tianjin Jinyuda Chemical Co., Ltd.
Tel
022-58013646 13011382049
Fax
022-23854368
Email
sales@jinyudachem.com
Country
China
ProdList
1889
Advantage
55
Synthetics China Co.,Ltd
Tel
0512-65218020; 18261037325
Email
ivy.shen@pharmsyn.com
Country
China
ProdList
101
Advantage
60
Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.
Tel
022-60116533 13207668525
Fax
022-60979672
Email
saleskc@scipharmacn.com
Country
China
ProdList
642
Advantage
58
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9865
Advantage
52
Shenyang Yuancheng Pharmaceutical Technology Co., Ltd.
Tel
024-31298370 15040047923
Fax
024-62665110
Email
yuanchengchem@163.com
Country
China
ProdList
252
Advantage
52
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Nanjing JinruiJiuAn Biotechnology Co., Ltd.
Tel
025-58196018 800028039
Fax
025-83453306
Email
sales@fartop.net
Country
China
ProdList
2229
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19915
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9545
Advantage
55
More
Less

View Lastest Price from Methyl 4-chloropicolinate manufacturers

Hebei Dangtong Import and export Co LTD
Product
Methyl 4-chloropicolinate 24484-93-3
Price
US $170.00-150.00/kg
Min. Order
100kg
Purity
99.99%
Supply Ability
100Tons
Release date
2023-03-06
Henan Fengda Chemical Co., Ltd
Product
Methyl 4-chloropicolinate 24484-93-3
Price
US $200.00-1.00/KG
Min. Order
1KG
Purity
99%, 99.5% Sublimated
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-30
Hebei Fengqiang Trading Co., LTD
Product
Methyl 4-chloropicolinate 24484-93-3
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-14

24484-93-3, Methyl 4-chloropicolinateRelated Search:

RESMETHRIN Clopidol Methyl acetate Methylparaben Bensulfuron methyl Pentachloropyridine 2-Chloro-3-hydroxypyridine Methyl formate Thiophanate-methyl Methyl acrylate 4-Chloropyridinium chloride METSULFURON METHYL 2-Chloro-5-chloromethylpyridine Kresoxim-methyl 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Methyl Sorafenib IMpurity Phenol, 4-(hydroxyamino)-

  • IFLAB-BB F2108-0101
  • METHYL 4-CHLOROPICOLINATE
  • 4-Chloropyridine-2- forMic acidMethyl ester
  • 4-chloropicolinate
  • Methyl 4-chloropicolite
  • Methyl 4-chloropyridine-2-car
  • EOS-62380
  • Methyl 4-chloropyridine-2-carboxylate 97%
  • METHYL 4-CHLOROPYRIDINE-2-CARBOXYLATE
  • METHYL 4-CHLORO-2-PYRIDINECARBOXYLATE
  • 4-CHLORO-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER
  • 6-Methyl-2-(trifluoromethanesulfonyl)Oxypyridine
  • Methyl 4-Chloro-2-picolinate
  • 4-Chloropicolinic Acid Methyl Ester Methyl 4-Chloropicolinate 4-Chloro-2-pyridinecarboxylic Acid Methyl Ester
  • 2-Pyridinecarboxylic acid, 4-chloro-, methyl ester
  • 4-Chloropicolinic Acid Methyl Ester
  • 4-Chloro-pyridine-2-carboxylic acid methyl
  • Methyl 4-chloro-2-pyridin...
  • Methyl 4-chloropicolinate, 4-Chloro-2-(methoxycarbonyl)pyridine
  • oro-2-pyridinecarboxyL
  • Methyl4-Chloro-2-pyridinecarboxylate&gt
  • 4-chloropyridine-2-formate
  • Methyl 4-chloropicolinate ISO 9001：2015 REACH
  • 4-chloropyridine-2-carboxylic acid methyl ester (intermediate of sorafenib)
  • 4-Chloro pyridine-2-carboxylic acid ME
  • 4-Chloro pyridine carboxylic acid methylester
  • 24484-93-3
  • 24482-93-3
  • pharmacetical
  • Pyridine
  • Aromatics Compounds
  • Aromatics
  • Bases & Related Reagents
  • Nucleotides
  • Pharmaceutical intermediate
  • blocks
  • Carboxes
  • Pyridines
  • Acids and Derivatives
  • Heterocycles
  • Picolinic acid series
  • OLED materials,pharm chemical,electronic