ChemicalBook > CAS DataBase List > Dipeptide-2

Dipeptide-2

Product Name
Dipeptide-2
CAS No.
24587-37-9
Chemical Name
Dipeptide-2
Synonyms
eyeliss;VAL-TRP;VW;VW-2;NH2-VW-OH;L-Val-Trp;DIPEPTIDE-2;H-VAL-TRP-OH;N-valyltryptophan;Dipeptide Val-Try
CBNumber
CB2227911
Molecular Formula
C16H21N3O3
Formula Weight
303.36
MOL File
24587-37-9.mol
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Dipeptide-2 Property

Boiling point:
604.8±55.0 °C(Predicted)
Density 
1.268±0.06 g/cm3(Predicted)
storage temp. 
−20°C
pka
3.14±0.10(Predicted)
form 
Solid
color 
White to off-white
Sequence
Val-Trp
InChI
InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1
InChIKey
LZDNBBYBDGBADK-KBPBESRZSA-N
SMILES
C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C(C)C)N
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
COS0000053
Product name
DIPEPTIDE-2
Purity
95.00%
Packaging
5MG
Price
$402.73
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
COS0000053
Product name
DIPEPTIDE-2
Purity
95.00%
Packaging
1G
Price
$946
Updated
2021/12/16
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Dipeptide-2 Chemical Properties,Usage,Production

Description

Dipeptide-2 is a tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags.
The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.

Chemical Properties

H-VAL-TRP-OH is a white or off-white lyophilized powder.

Uses

Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1]. Dipeptide 2 is an angiotensin-converting Enzyme (ACE)[2].

Definition

ChEBI: Dipeptide-2 is a synthetic peptide used for skin care.

Mode of action

Dipeptide-2 is a potent angiotensin-converting enzyme (ACE) inhibitor, which reduces vasoconstriction of blood vessels around the eyes by inhibiting ACE activity and promotes blood circulation, thus improving periorbital edema and reducing dark circles.

References

[1] Zhang L, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009;27(5):485-494. DOI:10.1016/j.clindermatol.2009.05.013
[2] Bicak B. Structural, spectroscopic, molecular docking, ADME, molecular dynamics studies of Val-Trp dipeptide. J Biomol Struct Dyn. 2023;41(23):13873-13890. DOI:10.1080/07391102.2023.2183041

Dipeptide-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Dipeptide-2 Suppliers

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View Lastest Price from Dipeptide-2 manufacturers

Chengdu Shengnuo Biopharm Co.,Ltd
Product
Dipeptide-2 24587-37-9
Price
US $500.00-500.00/kg
Min. Order
1kg
Purity
≥99.00%
Supply Ability
1000000
Release date
2025-10-10
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
Dipeptide-2 24587-37-9
Price
US $2.00-5.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-25
Huaian Banting Trading Co., Ltd.
Product
Dipeptide-2 24587-37-9
Price
US $100.00/PC
Min. Order
1PC
Purity
99%
Supply Ability
1000kg
Release date
2025-03-27

24587-37-9, Dipeptide-2Related Search:


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  • Amino Acid Derivatives