Dipeptide-2
- Product Name
- Dipeptide-2
- CAS No.
- 24587-37-9
- Chemical Name
- Dipeptide-2
- Synonyms
- eyeliss;VAL-TRP;VW;VW-2;NH2-VW-OH;L-Val-Trp;DIPEPTIDE-2;H-VAL-TRP-OH;N-valyltryptophan;Dipeptide Val-Try
- CBNumber
- CB2227911
- Molecular Formula
- C16H21N3O3
- Formula Weight
- 303.36
- MOL File
- 24587-37-9.mol
Dipeptide-2 Property
- Boiling point:
- 604.8±55.0 °C(Predicted)
- Density
- 1.268±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- pka
- 3.14±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- Sequence
- Val-Trp
- InChI
- InChI=1S/C16H21N3O3/c1-9(2)14(17)15(20)19-13(16(21)22)7-10-8-18-12-6-4-3-5-11(10)12/h3-6,8-9,13-14,18H,7,17H2,1-2H3,(H,19,20)(H,21,22)/t13-,14-/m0/s1
- InChIKey
- LZDNBBYBDGBADK-KBPBESRZSA-N
- SMILES
- C(O)(=O)[C@H](CC1C2=C(C=CC=C2)NC=1)NC(=O)[C@H](C(C)C)N
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- COS0000053
- Product name
- DIPEPTIDE-2
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $402.73
- Updated
- 2021/12/16
- Product number
- COS0000053
- Product name
- DIPEPTIDE-2
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $946
- Updated
- 2021/12/16
Dipeptide-2 Chemical Properties,Usage,Production
Description
Dipeptide-2 is a tiny peptide with only two amino acids (amino acids are the building block of proteins, and peptides are a few amino acids attached together), Valine and Tryptophan. It's part of a 3 actives complex called Eyeliss (with HMC and Palmitoyl Tetrapeptide-7) that's supposed to fight under-eye bags.
The manufacturer claims that this dipeptide in Eyeliss can increase lymphatic circulation and the three actives together represent a "global approach to treating puffy eyes". The clinical study of the manufacturer with 20 people and 3% Eyeliss showed improvement after 56 days for 70% of the participants.
Chemical Properties
H-VAL-TRP-OH is a white or off-white lyophilized powder.
Uses
Dipeptide 2 (N-Valyltryptophan; Val-Trp) is a bioactive peptide with anti-aging effect and has been reported used as a cosmetic ingredient[1]. Dipeptide 2 is an angiotensin-converting Enzyme (ACE)[2].
Definition
ChEBI: Dipeptide-2 is a synthetic peptide used for skin care.
Mode of action
Dipeptide-2 is a potent angiotensin-converting enzyme (ACE) inhibitor, which reduces vasoconstriction of blood vessels around the eyes by inhibiting ACE activity and promotes blood circulation, thus improving periorbital edema and reducing dark circles.
References
[1] Zhang L, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009;27(5):485-494. DOI:10.1016/j.clindermatol.2009.05.013
[2] Bicak B. Structural, spectroscopic, molecular docking, ADME, molecular dynamics studies of Val-Trp dipeptide. J Biomol Struct Dyn. 2023;41(23):13873-13890. DOI:10.1080/07391102.2023.2183041
Dipeptide-2 Preparation Products And Raw materials
Raw materials
Preparation Products
Dipeptide-2 Suppliers
- Tel
- --
- Fax
- --
- Country
- Switzerland
- ProdList
- 6896
- Advantage
- 91
- Tel
- --
- Fax
- --
- swiss@sennchem.com
- Country
- Switzerland
- ProdList
- 3143
- Advantage
- 71
View Lastest Price from Dipeptide-2 manufacturers
- Product
- Dipeptide-2 24587-37-9
- Price
- US $500.00-500.00/kg
- Min. Order
- 1kg
- Purity
- ≥99.00%
- Supply Ability
- 1000000
- Release date
- 2025-10-10
- Product
- Dipeptide-2 24587-37-9
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-25
- Product
- Dipeptide-2 24587-37-9
- Price
- US $100.00/PC
- Min. Order
- 1PC
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2025-03-27