ChemicalBook > CAS DataBase List > Cefmetazole sodium

Cefmetazole sodium

Product Name
Cefmetazole sodium
CAS No.
56796-39-5
Chemical Name
Cefmetazole sodium
Synonyms
C08104;Metafar;Cefmetazone;Cefmetazole-Na;Sodium cefmetazole;Cefmetazole sodium;CS-1170 sodium salt;Cefotetan Impurity 2;Cefmetazole Sodium Salt >Cefmetazole sodium USP/EP/BP
CBNumber
CB2231321
Molecular Formula
C15H18N7NaO5S3
Formula Weight
495.52
MOL File
56796-39-5.mol
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Cefmetazole sodium Property

Melting point:
>130°C (dec.)
storage temp. 
Inert atmosphere,2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
White to Off-White
Water Solubility 
Soluble in water
Sensitive 
Hygroscopic
Merck 
14,1926
Stability:
Hygroscopic
InChIKey
BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference
56796-39-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-42/43
Safety Statements 
26-36
WGK Germany 
2
RTECS 
XI0372200
HS Code 
2941.90.3000
Toxicity
LD50 i.v. in rats: >5000 mg/kg (Masuda)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C6048
Product name
Cefmetazole sodium salt
Packaging
1g
Price
$128
Updated
2024/03/01
Sigma-Aldrich
Product number
C6048
Product name
Cefmetazole sodium salt
Packaging
250mg
Price
$43
Updated
2023/06/20
TCI Chemical
Product number
C3029
Product name
Cefmetazole Sodium Salt
Purity
>97.0%(T)
Packaging
250mg
Price
$67
Updated
2024/03/01
TCI Chemical
Product number
C3029
Product name
Cefmetazole Sodium Salt
Purity
>97.0%(T)
Packaging
1g
Price
$237
Updated
2024/03/01
Alfa Aesar
Product number
J66348
Product name
Cefmetazole sodium, 921 μg/mg
Packaging
1g
Price
$87.65
Updated
2024/03/01
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Cefmetazole sodium Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial

Uses

Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.

brand name

Zefazone (Pharmacia & Upjohn）.

Clinical Use

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

Cefmetazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Cefmetazole sodium manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Cefmetazole sodium 56796-39-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000kg
Release date
2024-04-11
Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Cefmetazole sodium 56796-39-5
Price
US $0.00/Kg
Min. Order
1Kg
Purity
99%
Supply Ability
10kg
Release date
2024-04-09
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Cefmetazole sodium 56796-39-5
Price
US $0.00/KG/Tin
Min. Order
5KG
Purity
98%min
Supply Ability
500kg
Release date
2021-11-02

56796-39-5, Cefmetazole sodiumRelated Search:

Acetylacetone Sodium alginate Diclofenac sodium Sodium benzoate Acetaminophen Sodium citrate Sodium bicarbonate Sodium hydroxide Acetyl chloride Trisodium phosphate Sodium chloride Sodium acetate Acetyl coenzyme A sodium salt CEFMETAZOLE SODIUM SALT N-(2-HYDROXYETHYL)LACTAMIDE 3-AZETIDINOL 3-METHOXY-AZETIDINE N-N-bis(2-hydroxyethyl)formamide

  • Cefmetazone
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-
  • Cefmetazole-Na
  • CS-1170 sodium salt
  • Metafar
  • Sodium cefmetazole
  • (6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt
  • Cefmetazole sodium
  • Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt)
  • sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido
  • sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • (6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt
  • C08104
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[(cyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)-
  • Cefotetan Impurity 2
  • Cefmetazole Sodium Salt &gt
  • Cefmetazole sodium USP/EP/BP
  • Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
  • 56796-39-5
  • 59796-39-5
  • C15H16N7NaO5S3
  • C15H17N7O5S3
  • C15H16N7O5S3Na
  • Sulfur & Selenium Compounds
  • A - KAntibiotics
  • Antibacterial
  • Antibiotics A to
  • Antibiotics A-FAntibiotics
  • Chemical Structure Class
  • Interferes with Cell Wall SynthesisAntibiotics
  • Mechanism of Action
  • Penicillins and Cephalosporins (beta-Lactams)
  • Spectrum of Activity
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals