Cefmetazole sodium

Product Name: Cefmetazole sodium
CAS No.: 56796-39-5
Chemical Name: Cefmetazole sodium
Synonyms: C08104;Metafar;Cefmetazone;Cefmetazole-Na;Sodium cefmetazole;Cefmetazole sodium;CS-1170 sodium salt;Cefotetan Impurity 2;Cefmetazole Sodium Salt >Cefmetazole sodium USP/EP/BP
CBNumber: CB2231321
Molecular Formula: C15H18N7NaO5S3
Formula Weight: 495.52
MOL File: 56796-39-5.mol

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Cefmetazole sodium Property

Melting point:: >130°C (dec.)
storage temp.: Inert atmosphere,2-8°C
solubility: H2O: soluble50mg/mL
form: powder
color: White to Off-White
Water Solubility: Soluble in water
Sensitive: Hygroscopic
Merck: 14,1926
Stability:: Hygroscopic
InChIKey: BITQGIOJQWZUPL-PBCQUBLHSA-M
CAS DataBase Reference: 56796-39-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 36/37/38-42/43
Safety Statements: 26-36
WGK Germany: 2
RTECS: XI0372200
HS Code: 2941.90.3000
Toxicity: LD50 i.v. in rats: >5000 mg/kg (Masuda)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C6048
Product name: Cefmetazole sodium salt
Packaging: 1g
Price: $128
Updated: 2024/03/01

Sigma-Aldrich

Product number: C6048
Product name: Cefmetazole sodium salt
Packaging: 250mg
Price: $43
Updated: 2023/06/20

TCI Chemical

Product number: C3029
Product name: Cefmetazole Sodium Salt
Purity: >97.0%(T)
Packaging: 250mg
Price: $67
Updated: 2024/03/01

TCI Chemical

Product number: C3029
Product name: Cefmetazole Sodium Salt
Purity: >97.0%(T)
Packaging: 1g
Price: $237
Updated: 2024/03/01

Alfa Aesar

Product number: J66348
Product name: Cefmetazole sodium, 921 μg/mg
Packaging: 1g
Price: $87.65
Updated: 2024/03/01

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Cefmetazole sodium Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Semi-synthetic antibiotic derived from Cephamycin. Antibacterial

Uses

Cefmetazole sodium is used clinically in combination with Tanreqing for the treatment of Pulmonary infections like Senile Emphysema and other acute bacterial infections.

Definition

ChEBI: An organic sodium salt that is the sodium salt of cefmetazole.

brand name

Zefazone (Pharmacia & Upjohn）.

Clinical Use

Cefmetazole (Zefazone) is a semisynthetic, third-generation,parenteral cephalosporin of the cephamycin group. Likeother cephamycins, the presence of the 7α-methoxyl groupconfers resistance to many β-lactamases. Cefmetazoleexhibits significantly higher potency against members ofthe Enterobacteriaceae family but lower activity againstBacteroides spp. than cefoxitin. It is highly active againstN. gonorrhoeae, including -lactamase–producing strains. Incommon with other cephamycins, cefmetazole is ineffectiveagainst indole-positive Proteus, Enterobacter, Providencia,Serratia, and Pseudomonas spp. Cefmetazole has the MTTmoiety associated with increased bleeding in certain highriskpatients. It has a plasma half-life of 1.1 hours.

Cefmetazole sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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Cefmetazole sodium Suppliers

Americas 1 Canada 1 China 161 Europe 1 France 1 Germany 4 India 7 Japan 2 South Korea 9 Switzerland 4 United Kingdom 6 United States 28 Global 225

Kemprotec Limited (France)

Tel: --
Fax: --
Country: France
ProdList: 74
Advantage: 58

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View Lastest Price from Cefmetazole sodium manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Cefmetazole sodium 56796-39-5
Price: US $0.00/KG/Tin
Min. Order: 5KG
Purity: 98%min
Supply Ability: 500kg
Release date: 2021-11-02

Hebei Weibang Biotechnology Co., Ltd

Product: Cefmetazole sodium 56796-39-5
Price: US $1.00/PCS
Min. Order: 1PCS
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-31

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Cefmetazole sodium 56796-39-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000kg
Release date: 2024-04-11

56796-39-5, Cefmetazole sodiumRelated Search:

Acetylacetone Sodium alginate Diclofenac sodium Sodium benzoate Acetaminophen Sodium citrate Sodium bicarbonate Sodium hydroxide Acetyl chloride Trisodium phosphate Sodium chloride Sodium acetate Acetyl coenzyme A sodium salt CEFMETAZOLE SODIUM SALT N-(2-HYDROXYETHYL)LACTAMIDE 3-AZETIDINOL 3-METHOXY-AZETIDINE N-N-bis(2-hydroxyethyl)formamide

Cefmetazone

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7S)-

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R-cis)-

Cefmetazole-Na

CS-1170 sodium salt

Metafar

Sodium cefmetazole

(6R,7S)-7-[[2-[(Cyanomethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl -1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene -2-carboxylic Acid Sodium Salt

Cefmetazole sodium

Sodium (6R,7S)-7-[[2-(cyanomethylsulfanyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

Cefotetan Impurity 1 Sodium Salt (Cefmetazole Sodium Salt)

sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido

sodium (6R,7S)-7-[[2-(cyanomethylthio)-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

(6R)-7-[[[(Cyanomethyl)thio]acetyl]amino]-7β-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid sodium salt

C08104

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[2-[(cyanoMethyl)thio]acetyl]aMino]-7-Methoxy-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-,sodiuM salt (1:1), (6R,7S)-

Cefotetan Impurity 2

Cefmetazole Sodium Salt &gt

Cefmetazole sodium USP/EP/BP

Sodium (6R,7S)-7-(2-((cyanomethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

56796-39-5

59796-39-5

C15H16N7NaO5S3

C15H17N7O5S3

C15H16N7O5S3Na

Sulfur & Selenium Compounds

A - KAntibiotics

Antibacterial

Antibiotics A to

Antibiotics A-FAntibiotics

Chemical Structure Class

Interferes with Cell Wall SynthesisAntibiotics

Mechanism of Action

Penicillins and Cephalosporins (beta-Lactams)

Spectrum of Activity

Chiral Reagents

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals